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1974 STUDY: ANTINEOPLASTIC ACTIVITY OF CANNABINOIDS

Discussion in 'Topical Discussions (In Depth)' started by G-khan, Jan 11, 2018.



  1. G-khan

    G-khan Founding Member Founding Member

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    This is hidden study done in 1974 on Cannabis and Cancer!
    Requested by U.S Gov. then destroyed to cover up the results!

    https://www.cureyourowncancer.org/1...-antineoplastic-activity-of-cannabinoids.html
    Home | How Cannabis Oil Works | Make The Oil | Dosage | Store | Contact | Return Policy | Shipping Policy


    1974 STUDY: ANTINEOPLASTIC ACTIVITY OF CANNABINOIDS
    A.E. Munson, L.S. Harris, M.A. Friedman, W.L. Dewey, and R.A. Carchman
    Journal of the National Cancer Institute, Vol. 55, No. 3, September 1975


    Supported by Public Health Service grant DA00490 from the National Institute on Drug Abuse, Health Services & Mental Health Administration; by a grant from the Alexander and Margaret Stewart Trust Fund; and by an institutional grant from the American Cancer Society.

    Department of Pharmacology and the MCV/VCU Cancer Center, Medical College of Virginia, Virginia Commonwealth University. Richmond, Va. 23298


    Abstract:

    Lewis lung adenocarcinoma growth was retarded by the oral administration of delta-9-tetrahydrocannabinol, delta-8-tetrahydrocannabinol, and cannabinol (CBN), but not cannabidiol (CBD). Animals treated for 10 consecutive days with delta-9-THC, beginning the day after tumor implantation, demonstrated a dose-dependent action of retarded tumor growth. Mice treated for 20 consecutive days with delta-8-THC and CBN had reduced primary tumor size. CBD showed no inhibitory effect on tumor growth at 14, 21, or 28 days. Delta-9-THC, delta-8-THC, and CBN increased the mean survival time (36% at 100 mg/kg, 25% at 200 mg/kg, and 27% at 50 mg/kg;, respectively), whereas CBD did not. Delta-9-THC administered orally daily until death in doses of 50, 100, or 200 mg/kg did not increase the life-spans of (C57BL/6 X DBA/2) F (BDF) mice hosting the L1210 murine leukemia. However, delta-9-THC administered daily for 10 days significantly inhibited Friend leukemia virus-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for actinomycin D. Experiments with bone marrow and isolated Lewis lung cells incubated in vitro with delta-8-THC and delta-9-THC showed a dose-dependent (10 -4 10 -7) inhibition (80-20%, respectively) of tritiated thymidine and 14C -uridine uptake into these cells. CBD was active only in high concentrations (10 -4)

    Introduction:

    Investigations into the physiologic processes affected by the psychoactive constitutuents of marihuana [delta-9-tetrahydrocannabinol (delta-9-THC) and delta-8-tetrahydrocannabinol (delta-8-THC)] purified from Cannabis sativa are extensive (1). However, only recently have attempts been made to elucidate the biochemical basis for their cytotoxic or cytostatic activity. Leuchtenberger et al. (2) demonstrated that human lung cultures exposed to marihuana smoke showed alterations in DNA synthesis, with the appearance of anaphase bridges. Zimmerman and McClean (3), studying macromolecular synthesis in Tetrahymena, indicated that very low concentrations of delta-9-THC inhibited RNA, DNA, and protein synthesis and produced cytolysis. Stenchever et al. (4) showed an increase in the number of damaged or broken chromosomes in chronic users of marihuana. Delta-9-THC administered iv inhibited bone marrow leukopoieses (5), and Kolodny et al. (6) reported that marihuana; may impair testosterone secretion and spermatogenesis.

    Furthermore, Nahas et al. (7) showed that in chronic marihuana users there is a decreased lymphocyte reactivity to mitogens as measured by thymidine uptake. These and other (8) observations suggest that marihuana (delta-9-THC) interferes with vital cell biochemical processes, though no definite mechanism has yet been established. A preliminary report from this laboratory (9) indicated that the ability of delta-9-THC to interfere with normal cell functions might prove efficacious against neoplasms. This report represents an effort to test various cannabinoids in several in vivo and in vitro tumor systems to determine the kinds of tumors that are sensitive to these compounds and reveal their possible biochemical sites of action(s).

    Materials and methods

    The tumor systems used were the Lewis lung adenocarcinoma, leukemia L1210, and B-tropic Friend leukemia.

    In vivo systems.

    Lewis lung tumor: For the maintenance of the Lewis lung carcinoma, approximately 1-mm3 pieces of tumor were transplanted into C57BL/6 mice with a 15-gauge trocar. In experiments involving chemotherapy, 14- to 18-day-old tumors were excised, cleared of debris and necrotic tissue, and cut into small fragments (=1mm3). Tumor tissue was then placed in 0.25% trypsin in Dulbecco's medium with 100 U Penicillin/ml and 100 mcg streptomycin/ml. After 90 minutes' incubation at 22 Degrees C, trypsin action was stopped by the addition of complete medium containing heat-inactivated fetal calf serum (final concentration, 20%). Cells were washed two times in complete medium, enumerated in a Coulter counter (Model ZB1) or on a hemocytometer, and suspended in serum-free medium at a concentration of 5 X 10 6 cells / ml. Next 1 X 10 6 cells were injected into the right hind gluteur muscle, and drugs administered as described in "Results." Standard regimens provided for 10 consecutive daily doses beginning 24 hours after tumor inoculation. Body weights were recorded before tumor inoculation and weekly for 2 weeks. Tumor size was measured weekly for the duration of the experiment and converted to mg tumor weight, as described by Mayo (10).

    Friend leukemia: B-tropic Friend leukemia virus (FLV) was maintained in BALB / c mice, and drug evaluation performed in the same animals. Pools of virus were prepared from the plasma of mice given FLV and stored at -70 Degrees C. In experiments with FLV, 0.2 ml of a 1/20 dilution of plasma (derived from FLV-infected mice) in medium was inoculated ip into BALB / c mice. Cannabinoids were administered orally daily for 10 consecutive days beginning 24 hours after virus inoculation. Twenty-four hours after the last drug administration, the mice were killed by cervical dislocation, and the spleens removed and weighed. Mice not given FLV were treated as described above, to evaluate possible drug-induced splenomegaly.

    L1210 leukemia: The murine leukemia L1210 was maintained in DBA/2 mice by weekly transfers of 10 (to the fifth power) cells derived from the peritoneal cavity. In these experiments, 10 (fifth power) leukemia cells were inoculated ip into (C57BL/6 X DBA/2) F 1 (BDF 1) mice, and the mice were treated daily for 10 consecutive days beginning 24 hours after tumor cell inoculation. Mean survival time was used as an index of drug activity.

    In vitro cell systems

    Lewis lung tumor: We obtained isolated Lewis lung tumor cells by subjecting 1-mm (third power) sections of tumor to 0.25% trypsin at 22 degrees C and stirring for 60-90 minutes. After trypsinization, the cells were centrifuged (1,000 rpm for 10 min) and washed twice in Dulbecco's medium containing 20% heat-inactivated fetal calf serum. They were then reconstituted to 10 7 cells/ml of 200 mm glutamine, 5,000 U penicillin, and 5,000 mcg streptomycin. Tumor cells (3-6 ml) were dispensed into 25-ml Erlenmeyer flasks and preincubated with eithe the drug or the drug vehicle for 15 minutes in a Dubnoff metabolic shaker at 37 degrees C in an atmosphere of 5% CO2--95% )2. After preincubation, 10 ucl tritiated thymidine (3H-TDR) (10 uCi, 57 Ci/mmole; New England Nuclear Corp., Boston, Mas.) was added to each flask and incubated for various times, after which 1-ml aliquots were removed and placed in 10 X 75-mm test tubes containing 1 ml 10% trichloroacetic acid (TCA) at 4 degrees C. The TCA-precipated samples were then filtered on 0.45-u Millipore filters and washed twice with 5 ml of 10% TCA at 4 degrees C. The filters were transferred to liquid scintillation vials and counted in a toluene cocktail containing Liquifluor (New England Nuclear Corp.) (4 liters toluene to 160 ml Liquifluor). Samples were then counted in a liquid scintillator.

    Bone marrow: Bone marrow cells were derived from the tibias and fibulas of BDF 1 mice. One ml Dulbecco's medium containing 1 U heparin/ml was forced through each bone by a 1-ml syringe with a 26-gauge needle. The cells were washed three times, nucleated cells were enumerated on a hemocytometer, and cell viability was ascertained by trypan blue exclusion. Cell number was adjusted to 10 (seventh) cells/ml with heparin-free Dulbecco's medium and incubated at 4 degrees C for 15 minutes. Bone marrow cells were then dispensed (3-5 ml) into a25-ml Erlenmeyer flasks containing the test drug or the drug vehicle. This preincubation period was followed by the addition of 10 ul 3H-TDR and the procedures done as outlined for the isolated Lewis lung cells.

    L1210: L1210 cells were derived from DBA/2 mice as described above. They were obtained from DBA/2 mice and inoculated 7 days before the experiment by the peritoneal cavity being flushed with 10 ml Dulbecco's medium containing heparin (5 u/ml). The cells were washed three times in medium, and the final medium wash did not contain heparin. The cells were resuspended at 10 (seventh) cells/ml and treated as described above. Cells were routinely counted with a hemocytometer for the determination of cell viability with trypan blue; for Lewis lung tumor and L1210 cells, a Coulter apparatus (Mode ZB1) was also used. All other reagents were of the highest quality grade available. Actinomycin D, 5-fluorouracil (5-FU), and cytosine arabinoside (ara-C) were provided by the Drug Development Branch, National Cancer Institute (NCI).

    Cannabinoids: The structures of the four compounds are shown in text-figure 1.

    [​IMG]

    All occur naturally in marihuana and were chemically synthesized. These drugs were provided by the National Institute on Drug Abuse or the Sheehan Institute for Research, Cambridge, Massachusetts. In the preparation of the drugs, the cannabinoids were complexed to albumin or solubilized in Emulphor-alcohol. Both preparations produced similar antitumor activity. With albumin, the cannabinoids were prepared in the following manner: A stock solution of 150 mg cannabinoid per ml absolute ethanol was made. Six ml of this solution was placed in a 200-ml flask. The ethanol was evaporated off under a stream of nitrogen and 2,100 mg lyophilized bovine serum albumin (BSA) added. After the addition of 20 ml distilled water, the substances were stirred with a glass rod in a sonicator until a good suspension was achieved. Sufficient distilled water was the aldded to make the desired dilution. Concentrations were routinely checked with a gas chromatograph. When Emulphor-alcohol was used as the vehicle, the desired amount of cannabinoid was sonicated in a solution of equal volumes by absolute ethanol and Emulphor (El-620; GAF Corp., New York, N.Y.) and then diluted with 0.15 N NaCL for a final ratio of 1: 1: 4 (ethanol: Emulphor: NaCL).

    Results

    Effects of Cannabinoids on Murine Tumors

    Delta-9-THC, delta-8-THC, and cannabinol (CBN) all inhibited primary Lewis lung tumor growth, whereas cannabidiol (CBD) enhanced tumor growth.

    Oral administration of 25, 50, or 100 mg delta-9-THC/kg inhibited primary tumor growth by 48, 72, and 75% respectively, when measured 12 days post tumor inoculation (table 1).

    [​IMG]

    On day 19, mice given delta-9-THC had a 34% reduction in primary tumor size. On day 30, primary tumor size was 76% that of controls and only those given 100 mg delta-9-THC/kg had a significant increase in survival time (36%). Mice treated with a delta-9-THC showed a slight weight loss over the 2-week period (average loss, 0.3 g at 50 mg/kg and 0.1 g at 100 mg/kg). This can be compared to cyclo-ohosphamide, which caused weight loss approaching 20% (table 2).
    [​IMG]

    Delta-8-THC activity was similar to that of delta-9-THC when administered orally daily until death (table 2). However, as with delta-9-THC, primary tumor growth approached control values after 3 weeks. When measured 12 days post tumor inoculation, all doses (50-400 mg/kg) of delta-8-THC inhibited primary tumor growth between 40 and 60%. Significant inhibition was also seen on day 21, which was comparable to cyclophosphamide-treated mice. Although this was not the optimum regime for cyclophosphamide, it was the positive control protocol provided by the NCI (11). All mice given delta-8-THC survived significantly longer than controls, except those treated with 100 mg/kg. Mice given 50, 200, and 400 mg/kg delta-8-THC had an increased life-span of 22.6, 24.6, and 27.2%, respectively, as compared to 33% for mice treated with 20 mg cyclophosphamide/kg. Pyran copolymer, an immunopotentiator (12) when administered at 50 mg/kg, also significantly increased the survival time of the animals (39.3%).

    CBN, administered by gavage daily until death, demonstrated antitumor activity against the Lewis lung carcinoma when evaluated on day 14 post tumor inoculation (table 3).

    [​IMG]

    Primary tumor growth was inhibited by 77%, at doses of 100 mg/kg on day 14 but only by 11% on day 24. At 50 mg/kg on day 14 but only by 11% on day 24. At 50 mg/kg, CBN inhibited primary tumor growth by only 32% when measured on day 14, and no inhibition was observed on day 24; however, these animals did survive 27% longer.

    CBD, administered at 25 or 200 mg/kg daily until death, showed no tumor-inhibitory properties as measured by primary Lewis lung tumor size or survival time (table 4).

    [​IMG]

    In this experiment, CBD-treated mice showed enhanced primary tumor growth. However, the control tumor growth rate in this experiment was decreased as compared to the previous studies.

    Survival time of BDF 1 mice hosting L1210 leukemia was not prolonged by delta-9-THC treatment (table 5).

    [​IMG]

    Mice treated with delta-9-THC at doses of 50, 100, and 200 mg/kg administered orally daily until death, survived 8.5, 7.8, and 8.6 days, respectively, as compared to 8.6 days for mice treated with the diluent. However, delta-9-THC inhigited FLV-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for the positive control actinomycin D (0.25 mg/kg). Although there was a dose-related inhibition, only the high dose was statistically significant (table 6).
    [​IMG]

    Effect of Cannabinoids on Isolated Cells In Vitro

    Isolated cells incubated in vitro represent a simple, reliable, and, hopefully, predictive method for the monitoring of the effects of agents on several biochemical parameters at the same time. The incorporation of 3H-TDR into TCA-precipitable counts in isolated Lewis lung cells is shown in text-figure 2. Similar types of curves were seen for bone marrow and L1210 cells. In all instances, for 15-45 minutes there was a linear increase in 3H-TDR uptake into the TCA-precipitable fraction. Qualitatively, similar data (not shown) were seen after a pulse with 14C-uridine. Actinomycin D (1 mcg/ml) preferentially inhibited 14C-uridine incorporation after uridine uptake had decreased to less than 30% that of control (data not shown). This is indirect evidence that we were measuring RNA synthesis.

    Experiments (data not shown) done with 5-FU (10 -4 M) indicated that, in isolated bone marrow cells, both thymidine uptake with time by delta-9-THC (10 -5 M) on Lewis lung cells is depicted in text-figure 2.

    [​IMG]

    In this experiment, delta-9-THC caused a nonlinear uptake of 3H-TDR. At 30 minutes, uptake of 3H-TDR into the acid-precipitable fraction was about 50% that of control Longer incubations (i.e., 60 min) did not significantly change the uptake pattern for control and de;ta-9-THC treated tumor cells. The effect of several cannabinoids on the uptake of 3H-TDR into cells incubated in vitro indicated that delta-9-THC, delta-8-THC, and CBN produced a dose-dependent inhibition of radiolabel uptake in the three cell types (table 7). These results, presented as percent inhibition of radiolabel uptake as compared to control, represented an effect of cannabinoids on one aspect of macromolecular synthesis.

    CBD was the least active of the cannabinoids, but showed its greatest activity in the L1210 leukemia cells. Other data (not shown) indicate that these compounds similarly effect the uptake of 14C-uridine into the acid-precipitable fraction. Ara-C markedly inhibited 3H-TDR uptake more dramatically than did the cannabinoids (table 7). Note that delta-9-THC exhibited inhibitory properties in the isolated Lewis lung tumor and L1210 cells at concentrations that did not interfere with thymidine uptake into bone marrow cells. At certain concentrations of CBD (2,5 X 10 -6 and 2.5 X 10 -7M), radiolabel uptake was consistently stimulated in bone marrow cells and in several experiments with the isolated Lewis lung cells.

    Discussion

    We investigated four cannabinoids for antineoplastic activity against three animal tumor models in vivo and for cytotoxic or cystostatic activity in two tumor cell lines and bone marrow cells in vitro.

    The cannabinoids (delta-9-THC, delta-8-THC, and CBN) active in vivo against the Lewis lung tumor cells are also active in the in vitro systems. The differential sensitivity of delta-9-THC against Lewis lung cells versus bone marrow cells is unique in that delta-8-THC and CBN are equally active in these systems. Johnson and Wiersma (5) reported that delta-9-THC administered iv caused a reduction in bone marrow metamyelocytes and an increase in lymphocytes. It is unclear from the data whether this is a depression of myelopoiesis or if it represents a lymphocyte infiltration into the bone marrow. The use of isolated bone marrow cells, which represent a nonneoplastic rapidly proliferating tissue, enables the rapid evaluation and assessment of drug sensititity and specificity, and thereby may predict toxicity related to bone marrow suppression.

    CBD showed noninhibitory activity either against the Lewis lung cells in vivo or Lewis lung and bone marrow cells in vitro at 10 -5M an 10 -6M, respectively. Indeed, the tumor growth rate in mice treated with CBD was significantly increased over controls. This may, in part, be the consequence of the observation made in vitro (i.e., 10 -7M CBD stimulated thymidine uptake), which may be reflected by an increased rate of tumor growth. One problem related to the use of cannabinoids is the development of tolerance to many of its behavioral effects (13). It also appears that tolerance functions in the chemotherapy of neoplsms in that the growth of the Lewis lung tumor is initially markedly inhibited but, by 3 weeks, approaches that of vehicle-treated mice (tables 1, 3). This, in part, may reflect drug regimens, doses used, increased drug metabolism, or conversion to metabolites with antagonistic actions to delta-9-THC. It may also represent some tumor cell modifications rendering the cell insensitive to these drugs.

    Of further interest was the lack of activity of delta-9-THC against the L1210 in vivo, whereas the invitro L1210 studies indicated that delta-9-THC could effectively inhibit thymidine uptake. The apparent reason for this discrepancy may be related to the high growth fraction and the short doubling time of this tumor. The in vitro data does not indicate that the cannabinids possess that degree of activity; e.g., ara-C, which "cures" L1210 mice, is several orders of magnitude more potent on a molar basis than delta-9-THC in vitro.

    Inhibition of tumor growth and increased animal survival after treatment with delta-9-THC may, in part, be due to the ability of the drug to inhibit nucleic acid synthesis. Preliminary data with Lewis lung cells grown in tissue culture indicate that 10 -5M delta-9-THC inhibits by 50% the uptake of 3H-TDR into acid-precipitable counts over a 4-hour incubation period. Simultaneous determination of acid-soluble fractions did not show any inhibitory effects on radiolabeled uptake. Therefore, delta-9-THC may be acting at site(s) distal to the uptake of precursor. We are currently evaluating the acid-soluble pool to see if phosphorylation of precursor is involved in the action of delta-9-THC.

    These results lend further support to increasing evidence that, in addition to the well-known behavioral effects of delta-9-THC, this agent modifies other cell responses that may have greater biologic significance in that they have antineoplastic activity. The high doses of delta-9-THC (i.e., 200 mg/kg) are not tolerable in humans. On a body-surface basis, this would be about 17 mg/m(2) for mice. Extrapolation to a 60-kg man would require 1,020 mg for comparable dosage. The highest doses administered to man have been 250-300 mg (14). Whether only cannabinoids active in the central nervous system (CNS) exhibit this antineoplastic property is not the question, since CBN, which lacks marihuana-like psychoactivity, is quite active in our systems (15).

    With structure-activity investigations, more active agents may be designed and synthesized which are devoid of or have reduced CNS activity. That these compounds readily cross the blood-brain barrier and do not possess many of the toxic manifestations of presently used cytotoxic agents, makes them an appealing group of drugs to study.




    REFERENCES

    1. Singer AJ: Marihuana: Chemistry, pharmacology and patterns of social use. Ann NY Acad Sci 191: 3-261, 1971

    2. Leuchtenberger C, Leuchtenberger R, Schneider A: Effects of marijuana and tobacco smoke on human lung physiology. Nature 241: 137-139,1973

    3. Zimmerman AM, McClean DK: Action of narcotic and hallucinogenic agents on the cell cycle. In Drugs and the Cell Cycle (Zimmerman AM, Padilla GM. Cameron IL, eds.). New York, Academic Press, 1973, pp.67-94

    4. Stenchever MA, Kunysz TJ, Allen MA: Chromosome breakage in users of marihuana. Am J Obstet Gynecol 118: 105-113, 1974

    5. JohnsonRT, Wiersema V: Repression of bone marrow leukopoieses by delta-9-THC . Res Commun Chem Pathol Pharmacol 7: 613-616, 1974

    6. Kolodny RC, Masters WH, Kolodner RM, et al: Depression of plasma testosterone levels after chronic intensive marijuana use. N Engl J Med 290: 872-874, 1974

    7. Nahas GG, Suchu-Foca N, Armand JP, et al: Inhibition of cellular immunity in marihuana smokers. Science 183: 419-420, 1974

    8. Levy JA, Munson AE, Haris LS, et al: Effect of delta-8 and delta-9-tetrahydrocannabinol on the immunre response in mice. The Pharmacologist 16: 259, 1974

    9. Harris LS, Munson AE, Friedman MA, et al: Retardation of tumor growth by delta-9-tetradydrocannabinol. The Pharmacologist 16: 259, 1974

    10. Mayo JG: Biologic characterization of the subcutaneously implanted Lewis lung tumor. Cancer Chemother Rep 3: 325-330, 1972

    11. Geran RI, Greenberg NH, MacDonald MM, et al: Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother Rep 3: 13, 1972

    12 Munson AE, Regelson W, Lawrence W: The biphasic response of the reticuloendothelial system (RES) produced by pyran copolymer and its relationship to immunologic response. J Reticuloendothel Soc 7: 375-385, 1970

    13. McMillan DE, Dewey WL, Turk RF, et al: Blood levels of 3H-delta-9-tetrahydrocannabinol and its metabolites in tolerant and non-tolerant pigeons. Biochem Pharmacol 22: 383-397, 1973

    14. Jones RT: The 30-day trip-clinical studies of cannabis tolerance and dependence. Proceedings of the International Conference on the Pharmacology of Cannabis. Savanah, Georgia, 1974, p.29

    15. Hollister LE: Structure-activity relationships in man of cannabis constituents and homologs and metabolites of delta-9-tetrahydrocannabinol. Pharmacology 11: 3-11,


    1974
     
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  2. FunnyMoney

    FunnyMoney Silver Member Silver Miner

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    Sorry, I didn't read the article. Could you please give us a short summary? Does this mean that regular, small intake of Cannabis lowers one's risk of cancer?
     
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  3. Goldhedge

    Goldhedge Moderator Site Mgr Site Supporter

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    It kills cancer cells...
     
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  4. the_shootist

    the_shootist The war is here on our doorstep! Midas Member Site Supporter ++

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    That sounds like it might come in handy. Do you think Big Pharma knows about this?
     
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  5. arminius

    arminius Gold Member Gold Chaser Site Supporter ++

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    Just checked, and yes, it's on Granny Storm Crows List. Which IMHO, needs to be spread, far and wide...

    Granny Storm Crow's List

    ADD/ ADHD


    Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD
    http://www.onlinepot.org/medical/add&mmj.htm

    Cannabis as a medical treatment for attention deficit disorder
    http://www.chanvre-info.ch/info/en/C...treatment.html

    Cannabinoids effective in animal model of hyperactivity disorder
    http://www.cannabis-med.org/english/...l.php?id=162#4

    Cannabis 'Scrips to Calm Kids?
    http://www.foxnews.com/story/0,2933,117541,00.html

    Moderate cannabis use has a positive effect on treatment for cocaine dependence in patients with comorbid ADHD and cocaine dependence
    http://bbsnews.net/article.php/20061210235129584

    Cannabis Improves Symptoms of ADHD
    http://cache.search.yahoo-ht2.akadns...icp=1&.intl=us

    Fitness to drive in spite (because) of THC
    http://www.unboundmedicine.com/medli...use__of_THC%5D

    Recipe For Trouble (anecdotal)
    http://www.cbsnews.com/stories/2002/...in503022.shtml


    ADDICTION RISK- PHYSICAL

    Women's Guide to the UofC
    http://wguide.uchicago.edu/9substance.html

    Cannabis Basics
    http://www.erowid.org/plants/cannabi...s_basics.shtml

    10 Things Every Parent, Teenager & Teacher Should Know About Marijuana (4th Q)
    http://www.erowid.org/plants/cannabi...s_flyer1.shtml

    Marijuana Myths, Claim No. 9
    http://www.erowid.org/plants/cannabi...is_myth9.shtml

    Moderate cannabis use has a positive effect on treatment for cocaine dependence in patients with comorbid ADHD and cocaine dependence
    http://bbsnews.net/article.php/20061210235129584

    Excerpt from the Merck Manual
    http://www.ukcia.org/research/merck.htm

    Relative Addictiveness of Various Substances
    http://www.ukcia.org/research/addictiv.htm

    AIDS – see HIV

    ALCOHOLISM

    Role of cannabinoid receptors in alcohol abuse
    http://www.medicalnewstoday.com/articles/30338.php

    Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
    http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

    Cannabis substitution
    http://www.cannabis-med.org/studies/...ow.php?s_id=86

    Cannabis as a Substitute for Alcohol
    http://ccrmg.org/journal/03sum/substitutealcohol.html

    The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism
    http://www.pubmedcentral.nih.gov/art...?artid=1975858

    ALLERGIES TO CANNABIS

    Sensitization and Allergy to Cannabis sativa Leaves in a Population of Tomato Sensitized Patients.
    http://marijuana.researchtoday.net/archive/5/2/1629.htm

    Allergic rhinoconjunctivitis caused by Cannabis sativa pollen
    http://www.drugs-forum.com/forum/loc...=4823&catid=21

    Allergic Skin Test Reactivity to Marijuana in the Southwest
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez


    ALS/ Amyotrophic Lateral Sclerosis

    Cannabinol delays symptom onset
    http://www.ncbi.nlm.nih.gov/sites/en..._uids=16183560

    Marijuana in the management of amyotrophic lateral sclerosis
    http://www.medscape.com/medline/abstract/11467101 (may need free registration)

    Cannabis use in patients with amyotrophic lateral sclerosis. (may need free registration)http://www.medscape.com/medline/abstract/15055508

    Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease
    http://www.illinoisnorml.org/index2....o_pdf=1&id=104

    ALZHEIMER'S

    MARIJUANA SLOWS ALZHEIMER'S DECLINE
    http://www.mapinc.org/drugnews/v05/n307/a10.html

    Marijuana may block Alzheimer's
    http://news.bbc.co.uk/2/hi/health/4286435.stm

    Prevention of Alzheimer's Disease Pathology by Cannabinoids
    http://www.jneurosci.org/cgi/content/abstract/25/8/1904

    Marijuana's Active Ingredient Shown to Inhibit Primary Marker of Alzheimer's Disease
    http://www.pacifier.com/~alive/articles/ca060809.htm

    Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    Dronabinol in the treatment of refractory agitation in Alzheimer’s disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=92

    Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
    http://www.cannabis-med.org/studies/...ow.php?s_id=59

    Cannabinoids reduce the progression of Alzheimer's disease in animals
    http://www.cannabis-med.org/english/...l.php?id=187#1

    Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology
    http://www.unboundmedicine.com/medli...ease_Pathology

    THC inhibits primary marker of Alzheimer's disease
    http://www.cannabis-med.org/english/...l.php?id=225#3

    Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats
    http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

    Alzheimer's disease; taking the edge off with cannabinoids?
    http://www.nature.com/bjp/journal/v1.../0707446a.html

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Inflammation and aging: can endocannabinoids help?
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    AMOTIVATIONAL SYNDROME

    Amotivational Syndrome
    http://leda.lycaeum.org/?ID=12454

    Marijuana Myths, Claim No. 11
    http://www.erowid.org/plants/cannabi...s_myth11.shtml

    Debunking 'Amotivational Syndrome'
    http://www.mapinc.org/drugnews/v06/n400/a06.html

    Debunking the Amotivational Syndrome
    http://www.drugscience.org/Petition/C3F.html

    Cannabis Use Not Linked To So-Called "Amotivational Syndrome"
    http://norml.org/index.cfm?Group_ID=6824


    ANECDOTAL / PERSONAL STORIES

    Shared Comments and Observations
    http://www.rxmarihuana.com/comments_...servations.htm

    Cannabis Sativa (Marijuana) for Fibromyalgia
    http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm

    ANECDOTAL ARTICLES
    http://cannabislink.ca/medical/#medanecdotal

    Testimonials
    http://www.benefitsofmarijuana.com/testimonials.html

    Bud Buddies
    http://budbuddies.com/buddy_testimonials.htm

    ANTI-BACTERIAL PROPERTIES

    Antibacterial Cannabinoids from Cannabis sativa
    http://pubs.acs.org/cgi-bin/sample.c...np8002673.html

    Killing bacteria with cannabis
    http://arstechnica.com/journals/scie...-with-cannabis

    Chemicals in Marijuana May Fight MRSA
    http://www.webmd.com/news/20080904/m...may-fight-mrsa

    ANTI-INFLAMMATORY PROPERTIES

    ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
    http://www.ukcia.org/research/Analge...stituents.html

    Why Cannabis Stems Inflammation
    http://www.sciencedaily.com/releases...0720222549.htm

    Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
    http://www.unboundmedicine.com/medli...titis_in_rats_

    #Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression (Alzheimer's)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Inflammation and aging: can endocannabinoids help?
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    ANTI-OXIDANT PROPERTIES

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    ANOREXIA-see APPETITE STIMULANT

    ANXIOLYTIC EFFECTS

    Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
    http://www.scielo.br/scielo.php?pid=...i_arttext#Te xt

    The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings
    http://fampra.oxfordjournals.org/cgi...bstract/cmn049

    The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety
    http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC.

    Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
    http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

    Single-dose study of nabilone in anxious volunteers.
    http://www.cannabis-med.org/studies/...blood,pressure

    APPETITE STIMULANT

    Dronabinol an effective appetite stimulant?
    http://www.cannabis-med.org/studies/...w.php?s_id=188

    THC improves appetite and reverses weight loss in AIDS patients
    http://www.cannabis-med.org/studies/...w.php?s_id=189

    Efficacy of dronabinol alone and in combination
    http://www.cannabis-med.org/studies/...w.php?s_id=191

    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
    http://www.cannabis-med.org/studies/...w.php?s_id=180

    Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=59

    Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.
    http://www.cannabis-med.org/studies/...ow.php?s_id=21

    Delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia
    http://www.cannabis-med.org/studies/...ow.php?s_id=52

    Effect of dronabinol on nutritional status in HIV infection.
    http://www.cannabis-med.org/studies/...w.php?s_id=150

    Dronabinol stimulates appetite and causes weight gain in HIV patients.
    http://www.cannabis-med.org/studies/...ow.php?s_id=20

    Dronabinol effects on weight in patients with HIV infection.
    http://www.cannabis-med.org/studies/...ow.php?s_id=45

    Recent clinical experience with dronabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=90

    Dronabinol enhancement of appetite in cancer patients.
    http://www.cannabis-med.org/studies/...w.php?s_id=149

    Effects of smoked marijuana on food intake and body weight
    http://www.cannabis-med.org/studies/...w.php?s_id=117

    Behavioral analysis of marijuana effects on food intake in humans.
    http://www.cannabis-med.org/studies/...w.php?s_id=118

    Cancer-related anorexia-cachexia syndrome
    http://www.unboundmedicine.com/medli...ia_Study_Group

    THC effective in appetite and weight loss in severe lung disease (COPD)
    http://www.cannabis-med.org/english/...l.php?id=191#2

    Machinery Of The 'Marijuana Munchies'
    http://www.sciencedaily.com/releases...1226102503.htm

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-in-Cachexia-Study-Group.
    http://www.medscape.com/medline/abst...49753?prt=true

    Factors influencing the aggressiveness elicited by marihuana in food-deprived rats
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Immunoactive cannabinoids: Therapeutic prospects for marijuana constituentshttp://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    ARTHRITIS

    Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
    http://www.pnas.org/cgi/content/full/97/17/9561

    The Cannabinergic System as a Target for Anti-inflammatory Therapies
    http://www.ingentaconnect.com/conten...00013/art00008

    Sativex in the treatment of pain caused by rheumatoid arthritis
    http://rheumatology.oxfordjournals.o. ..stract/45/1/50

    Suppression of fibroblast metalloproteinases by ajulemic acid,
    http://www.ncbi.nlm.nih.gov/pubmed/16927387

    The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
    http://www.unboundmedicine.com/medli...inoid_receptor

    Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
    http://www.unboundmedicine.com/medli..._arthritic_rat

    Cannabis based medicine eases pain and suppresses disease
    http://www.medicalnewstoday.com/articles/33376.php

    Pot-Based Drug Promising for Arthritis
    http://www.webmd.com/rheumatoid-arth...-for-arthritis

    Anti-inflammatory compound from cannabis found in herbs
    http://www.rsc.org/chemistryworld/Ne...e/24060801.asp

    ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
    http://www.ukcia.org/research/Analge...stituents.html

    US Patent 6132762 - Transcutaneous application of marijuana
    http://www.patentstorm.us/patents/6132762.html

    Cannabis May Suppress Immune System
    http://lupus.webmd.com/news/20030415...-immune-system

    ASTHMA

    The Cannabinergic System as a Target for Anti-inflammatory Therapies
    http://www.ingentaconnect.com/conten...00013/art00008

    Acute and subacute bronchial effects of oral cannabinoids.
    http://www.cannabis-med.org/studies/...ow.php?s_id=44

    Comparison of bronchial effects of nabilone and terbutaline
    http://www.cannabis-med.org/studies/...ow.php?s_id=43

    Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...w.php?s_id=109

    Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
    http://www.cannabis-med.org/studies/...ow.php?s_id=60

    Effects of smoked marijuana in experimentally induced asthma.
    http://www.cannabis-med.org/studies/...ow.php?s_id=57

    Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
    http://www.cannabis-med.org/studies/...ow.php?s_id=67

    New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
    http://www.medicalnewstoday.com/articles/22937.php

    Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
    http://www.ukcia.org/research/Smoked...nAsthmatic.php

    ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
    http://www.ukcia.org/research/Analge...stituents.html

    ATHEROSCLEROSIS

    Marijuana Chemical Fights Hardened Arteries
    http://www.webmd.com/heart-disease/n...dened-arteries

    Does Cannabis Hold the Key to Treating Cardiometabolic Disease (may need free registration)
    http://www.medscape.com/viewarticle/525040_print

    Cannabis may keep arteries clear
    http://www.gnn.tv/headlines/2634/Can...arteries_clear

    The Cannabinergic System as a Target for Anti-inflammatory Therapies
    http://www.ingentaconnect.com/conten...00013/art00008

    Cannabis compound tackles blood vessel disease
    http://www.medicalnewstoday.com/articles/22658.php

    Medical marijuana: study shows that THC slows atherosclerosis
    http://thenexthurrah.typepad.com/the...l_marijua.html

    Cardiovascular Effects of Cannabis
    http://www.idmu.co.uk/canncardio.htm

    Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    AUTISM

    Autism and Medical Marijuana
    http://autism.com/treatable/drug/marijuana_org.htm

    THE SAM PROJECT: James D.
    http://www.letfreedomgrow.com/articles/james_d.htm

    Medical marijuana: a valuable treatment for autism?
    http://www.autismwebsite.com/ari/new.../marijuana.htm

    Sam’s Story: Using Medical Cannabis to Treat Autism Spectrum Disorder
    http://www.letfreedomgrow.com/cmu/SamsStory.htm

    BIPOLAR DISORDER

    The Use of Cannabis as a Mood Stabilizer in Bipolar Disorder: Anecdotal Evidence and the Need for Clinical Research
    http://www.ukcia.org/research/TheUse...rDisorder.html

    Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential.
    http://www.ncbi.nlm.nih.gov/pubmed/1...,f1000m,isrctn

    Recipe For Trouble (anecdotal)
    http://www.cbsnews.com/stories/2002/...in503022.shtml

    The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study.
    http://www.cannabis-med.org/studies/...w.php?s_id=247

    BLOOD PRESSURE

    Lowering of Blood Pressure Through Use of Hashish
    http://www.thehempire.com/index.php/...use_of_hashish

    Blood Pressure Lowered With Cannabis Component
    http://www.thehempire.com/index.php/...abis_component

    BRAIN CELLS- see NEURONS

    BRAIN- PHYSICAL EFFECTS

    Effects of frequent marijuana use on brain tissue volume and composition
    http://www.ukcia.org/research/Effect...omposition.htm

    BONES- see OSTEOPOROSIS

    CANCER- BREAST

    Anandamide inhibits human breast cancer cell proliferation
    http://www.pnas.org/cgi/content/abstract/95/14/8375

    Inhibition of Human Breast and Prostate Cancer Cell Proliferation1
    http://endo.endojournals.org/cgi/con...ract/141/1/118

    Antitumor Activity of Plant Cannabinoids
    http://jpet.aspetjournals.org/cgi/co...act/318/3/1375

    9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
    http://cancerres.aacrjournals.org/cg...act/66/13/6615

    Cannabidiol inhibits tumour growth in leukaemia and breast cancer
    http://www.cannabis-med.org/english/...l.php?id=220#2

    THC and prochlorperazine effective in reducing vomiting in women following breast surgery
    http://www.cannabis-med.org/english/...l.php?id=219#1

    Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth
    http://www.thehempire.com/index.php/...wth_study_says

    “Medical Marijuana” Takes On New Meaning for Metastatic Breast Cancer
    http://www.healthcentral.com/breast-.../takes-cancer/

    Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells
    http://bbsnews.net/article.php/20071124003153693

    JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells
    http://www.knockoutscience.com/showa...?pmid=18454173

    Cannabis Compound May Stop Metastatic Breast Cancer
    http://www.washingtonpost.com/wp-dyn...111900834.html


    CANCER- CERVICAL

    Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells
    http://www.sciencedirect.com/science...a344307d083fe1

    Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
    http://www.webmd.com/cancer/news/200...r-in-test-tube

    CANCER- COLORECTAL

    Anandamide, induces cell death in colorectal carcinoma cells
    http://gut.bmj.com/cgi/content/abstract/54/12/1741

    Cannabinoids and cancer: potential for colorectal cancer therapy. (may need free registration)
    http://www.medscape.com/medline/abstract/16042581


    Marijuana takes on colon cancer
    http://www.newscientist.com/article/...9_head_dn14451

    Cannabis compound clue to colon cancer
    http://www.newscientist.com/channel/...-alcohol_rss20


    CANCER- GLIOMA/ BRAIN

    Anti-tumor effects of cannabidiol
    http://www.hempworld.com/HempPharm/a...ilanstudy.html

    Pot’s cancer healing properties
    http://www.november.org/stayinfo/bre...cerKiller.html

    Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
    http://cancerres.aacrjournals.org/cg...ort/64/16/5617

    Inhibition of Glioma Growth in Vivo
    http://cancerres.aacrjournals.org/cg...61/15/5784.pdf

    Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
    http://www.cannabis-med.org/studies/...w.php?s_id=193

    Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
    http://www.ihop-net.org/UniPub/iHOP/...?pmid=16909207

    Cannabis extract makes brain tumors shrink, halts growth of blood vessels
    http://www.medicalnewstoday.com/articles/12088.php

    THC tested against brain tumour in pilot clinical study
    http://www.cannabis-med.org/english/...l.php?id=222#1

    THC inhibits cell cycle progression in human glioblastoma multiforme cells
    http://marijuana.researchtoday.net/a.../4/10/1467.htm

    Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas
    http://marijuana.researchtoday.net/a.../4/12/1563.htm

    Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
    http://marijuana.researchtoday.net/archive/5/3/1697.htm

    Anti-Tumor Effects
    http://www.ukcia.org/research/AntiTumorEffects.htm

    Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
    http://cancerres.aacrjournals.org/cg...urcetype=HWCIT

    Marijuana ingredient may reduce tumours-study
    http://www.alertnet.org/thenews/newsdesk/LV470563.htm

    Active Ingredient in Marijuana Kills Brain Cancer Cells
    http://news.yahoo.com/s/hsn/20090401...aincancercells

    Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
    http://www.jci.org/articles/view/37948

    Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CANCER- LEUKEMIA

    Cannabis-induced cytotoxicity in leukemic cell lines
    http://bloodjournal.hematologylibrar. ..act/105/3/1214

    Cannabidiol-Induced Apoptosis in Human Leukemia Cells
    http://molpharm.aspetjournals.org/cg...tract/70/3/897

    Marijuana's Active Ingredient Kills Leukemia Cells
    http://www.treatingyourself.com/vbul...ead.php?t=7107

    Targeting CB2 cannabinoid receptors to treat malignant lymphoblastic disease
    http://bloodjournal.hematologylibrar. ../100/2/627.pdf

    Cannabinoids induce incomplete maturation of cultured human leukemia cells (1987)
    http://www.osti.gov/energycitations/...sti_id=5164483

    {Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
    http://mcr.aacrjournals.org/cgi/cont...stract/4/8/549

    Cannabidiol inhibits tumour growth in leukaemia and breast cancer
    http://www.cannabis-med.org/english/...l.php?id=220#2

    Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
    http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

    CANCER- LUNG

    Antineoplastic activity of cannabinoids
    http://www.ukcia.org/research/Antine...s/default.html

    Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration
    http://www.unboundmedicine.com/medli...stasis_in_vivo

    Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways
    http://ccrmg.org/journal/05aut/nocancer.html

    No association between lung cancer and cannabis smoking in large study
    http://www.cannabis-med.org/english/...l.php?id=219#2

    Marijuana Smoking Found Non-Carcinogenic
    http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

    CLAIM #4: MARIJUANA CAUSES LUNG DISEASE
    http://www.erowid.org/plants/cannabi...is_myth4.shtml

    Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
    http://www.webmd.com/cancer/news/200...r-in-test-tube

    Marijuana May Fight Lung Tumors
    http://www.webmd.com/lung-cancer/new...ht-lung-tumors

    Anti-Tumor Effects
    http://www.ukcia.org/research/AntiTumorEffects.htm

    Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
    http://cancerres.aacrjournals.org/cg...urcetype=HWCIT

    CANCER- LYMPHOMA

    Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents
    http://www.pacifier.com/~alive/cmu/c...d_lymphoma.htm

    CANCER- MELANOMA

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
    http://www.cannabis-med.org/studies/...w.php?s_id=180

    Intractable nausea and vomiting due to gastrointestinal mucosal metastases
    http://www.cannabis-med.org/studies/...ow.php?s_id=35

    CANCER- ORAL

    Smoking of cannabis does not increase risk for oral cancer
    http://www.cannabis-med.org/english/...l.php?id=175#1

    Marijuana use and Risk of Oral Squamous Cell Carcinoma
    http://web.archive.org/web/200601121...lCarcinoma.pdf

    CANCER- PANCREATIC

    Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells
    http://cancerres.aacrjournals.org/cg...act/66/13/6748

    CANCER- PROSTATE

    Inhibition of Human Breast and Prostate Cancer Cell Proliferation
    http://endo.endojournals.org/cgi/con...ract/141/1/118

    Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
    http://cancerres.aacrjournals.org/cg.../65/5/1635.pdf

    CANCER- RISK CANNABIS VS TOBACCO


    Cannabis Smoke and Cancer: Assessing the Risk
    http://www.norml.org/index.cfm?Group_ID=6891

    Cannabis and tobacco smoke are not equally carcinogenic
    http://www.pubmedcentral.nih.gov/art...?artid=1277837

    Smoking Marijuana Does Not Cause Lung Cancer
    http://www.mapinc.org/drugnews/v05/n1065/a03.html

    Blunt Smokers Link Dependence Potential To Nicotine
    http://www.medicalnewstoday.com/articles/52838.php

    Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco
    http://cannabislink.ca/medical/safer.html

    Why Doesn't Smoking Marijuana Cause Cancer?
    http://www.healthcentral.com/drdean/408/14275.html

    Marijuana Smoking Found Non-Carcinogenic
    http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

    CANCER- SKIN

    Inhibition of skin tumor growth
    http://www.jci.org/cgi/content/full/...=MpUgjDbqHybAU

    Cannabis Reduces Skin Cancer
    http://www.onlinepot.org/medical/skincancerreport.htm

    CANCER- TESTICULAR

    The antiemetic efficacy of nabilone
    http://www.cannabis-med.org/studies/...w.php?s_id=127

    Chemotherapy for Testicular Cancer
    http://www.rxmarihuana.com/shared_co...cularchemo.htm

    CANCER- VARIOUS/ UNNAMED

    Derivatives of cannabis for anti-cancer treatment
    http://www.eurekalert.org/pub_releas...o-do060605.php

    Cancer Killer
    http://www.november.org/stayinfo/bre...cerKiller.html

    Anandamide Induces Apoptosis
    http://www.jbc.org/cgi/content/abstract/275/41/31938

    Nabilone improves pain and symptom management
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    The effects of smoked cannabis in painful peripheral neuropathy
    http://www.cannabis-med.org/studies/...ow.php?s_id=96

    Delta-9-tetrahydrocannabinol for appetite stimulation
    http://www.cannabis-med.org/studies/...ow.php?s_id=52

    Dronabinol and prochlorperazine in combination
    http://www.cannabis-med.org/studies/...ow.php?s_id=28

    Dronabinol enhancement of appetite in cancer patients.
    http://www.cannabis-med.org/studies/...w.php?s_id=149

    Efficacy of tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...ow.php?s_id=31

    Nabilone versus domperidone
    http://www.cannabis-med.org/studies/...w.php?s_id=129

    Inhalation marijuana as an antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=155

    Nabilone vs. placebo in chemotherapy-induced nausea and vomiting
    http://www.cannabis-med.org/studies/...w.php?s_id=156

    The antiemetic activity of tetrahydrocanabinol versus metoclopramide
    http://www.cannabis-med.org/studies/...ow.php?s_id=24

    Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy
    http://www.cannabis-med.org/studies/...how.php?s_id=5

    Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
    http://www.cannabis-med.org/studies/...ow.php?s_id=23

    Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy
    http://www.cannabis-med.org/studies/...ow.php?s_id=27

    Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC
    http://www.cannabis-med.org/studies/...w.php?s_id=107

    Superiority of nabilone over prochlorperazine as an antiemetic
    http://www.cannabis-med.org/studies/...w.php?s_id=126

    Analgesic effect of delta-9-tetrahydrocannabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=16

    The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
    http://www.cannabis-med.org/studies/...ow.php?s_id=17

    Comparison of orally administered cannabis extract and delta-9-THC
    http://www.unboundmedicine.com/medli...ia_Study_Group

    Cannabis May Help Combat Cancer-causing Herpes Viruses
    http://www.sciencedaily.com/releases...0923092627.htm

    Marijuana Smoking Found Non-Carcinogenic
    http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

    HU-331, is More Potent and Less Cardiotoxic than Doxorubicin
    http://jpet.aspetjournals.org/cgi/co...ract/322/2/646

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Anti-Tumor Effects
    http://www.ukcia.org/research/AntiTumorEffects.htm

    Cannabinoids for Cancer Treatment: Progress and Promise
    http://cancerres.aacrjournals.org/cg.../full/68/2/339

    Cannabinoids and cancer: pros and cons of an antitumour strategy
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CANNABIDIOL

    Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
    http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

    Cannabinol delays symptom onset
    http://www.ncbi.nlm.nih.gov/sites/en..._uids=16183560

    Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
    http://www.pnas.org/cgi/content/full/97/17/9561

    Cannabidiol inhibits tumour growth in leukaemia and breast cancer
    http://www.cannabis-med.org/english/...l.php?id=220#2

    Anti-tumor effects of cannabidiol
    http://www.hempworld.com/HempPharm/a...ilanstudy.html

    Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
    http://www.ihop-net.org/UniPub/iHOP/...?pmid=16909207

    Cannabidiol-Induced Apoptosis in Human Leukemia Cells
    http://molpharm.aspetjournals.org/cg...tract/70/3/897

    Cannabidiol inhibits tumour growth in leukaemia and breast cancer
    http://www.cannabis-med.org/english/...l.php?id=220#2

    Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
    http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

    Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol
    http://ajp.amjpathol.org/cgi/content/full/168/1/235

    Evaluation of cannabidiol in dystonic movement disorders
    http://www.cannabis-med.org/studies/...ow.php?s_id=14

    Cannabidiol in dystonic movement disorders.
    http://www.cannabis-med.org/studies/...w.php?s_id=139

    Beneficial and adverse effects of cannabidiol in a Parkinson patient
    http://www.cannabis-med.org/studies/...w.php?s_id=142

    Treatment of Meige's syndrome with cannabidiol.
    http://www.cannabis-med.org/studies/...w.php?s_id=114

    CANNABIDIOL TO HEALTHY VOLUNTEERS AND EPILEPTIC PATIENTS
    http://web.acsalaska.net/~warmgun/es201.html

    Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
    http://www.cannabis-med.org/studies/...ow.php?s_id=42

    Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
    http://www.unboundmedicine.com/medli..._peroxynitrite

    EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE
    http://www.druglibrary.org/schaffer/...l/hunting1.htm

    The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.
    (may need free registration)
    http://www.medscape.com/medline/abstract/16209908

    Cannabidiol has a cerebroprotective action
    http://www.unboundmedicine.com/medli...ting_mechanism

    Cannabidiol as an antipsychotic
    http://www.cannabis-med.org/studies/...w.php?s_id=171

    Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
    http://www.medscape.com/medline/abst...44117?prt=true

    Who's Afraid of Cannabidiol?
    http://www.counterpunch.org/gardner07142007.html

    Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
    http://bbsnews.net/article.php/20070916110536662

    Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
    http://marijuana.researchtoday.net/archive/5/6/1797.htm

    Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
    http://www.scielo.br/scielo.php?pid=...i_arttext#Te xt

    Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria
    http://findarticles.com/p/articles/m...s_/ai_n9299539

    Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
    http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

    Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
    http://www.cannabis-med.org/studies/...ttern=EPILEPSY

    Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
    http://www.unboundmedicine.com/medli...titis_in_rats_

    The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
    http://www.unboundmedicine.com/medli...nducing_agent_

    Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
    http://cancerres.aacrjournals.org/cg...full/64/6/1943


    Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol
    http://www.pubmedcentral.nih.gov/art...?artid=2279017

    The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CARDIOVASCULAR- see HEART DISEASE

    CESAMET- see NABILONE

    CHEMICAL COMPOSITION

    Cannabis: A source of useful pharma compounds
    http://www.medpot.net/forums/index.php?showtopic=18608

    Pharmacokinetics and cannabinoid action using oral cannabis extract
    http://www.pharma-lexicon.com/medica...p?newsid=29638

    The chemistry and biological activity of cannabis
    http://www.unodc.org/unodc/en/data-a...2_page005.html

    Differential effects of medical marijuana based on strain and route of administration
    http://www.ukcia.org/research/DifferentialEffects/

    Cannabis / Marijuana ( Δ 9 -Tetrahydrocannabinol, THC)
    http://www.nhtsa.dot.gov/people/inju...s/cannabis.htm

    A chemotaxonomic analysis of cannabinoid variation in Cannabis
    http://www.amjbot.org/cgi/content/full/91/6/966

    The inheritance of chemical phenotype in Cannabis sativa L.
    http://www.genetics.org/cgi/reprint/163/1/335.pdf

    Medical Cannabis Potency Testing Project
    http://www.maps.org/news-letters/v09n3/09320gie.html

    Compounds found in Cannabis Sativa
    http://www.ukcia.org/research/cannabis-compounds.htm

    Hemp Seed Oil : The Wonder Oil For the New Millennium
    http://www.ukcia.org/research/Happi/...Millennium.htm

    Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria
    http://findarticles.com/p/articles/m...s_/ai_n9299539

    Non-cannabinoid constituents from a high potency Cannabis sativa variety.
    http://www.unboundmedicine.com/medli...ativa_variety_

    Cannabinoid Ester Constituents from High-Potency Cannabis sativa.
    http://www.unboundmedicine.com/medli...nnabis_sativa_

    Phytochemical and genetic analyses of ancient cannabis from Central Asia
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Plant cannabinoids: a neglected pharmacological treasure trove
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabis confusions
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Evaluation of herbal cannabis characteristics by medical users: a randomized trial
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CHEMOTHERAPY

    Efficacy of dronabinol alone and in combination
    http://www.cannabis-med.org/studies/...in,combination

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
    http://lib.bioinfo.pl/pmid:16408219

    An efficient new cannabinoid antiemetic in pediatric oncology
    http://www.druglibrary.org/olsen/hemp/iha/iha02210.html

    Dronabinol and prochlorperazine in combination
    http://www.ncbi.nlm.nih.gov/pubmed/1652611

    Marijuana as antiemetic medicine
    http://www.maps.org/docs/doblin-mt.html

    Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy
    http://www.cannabis-med.org/studies/...ow.php?s_id=31

    Inhalation marijuana as an antiemetic for cancer chemotherapy.
    http://www.crrh.org/oldest/vinciguerra.html

    Nabilone versus prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=120

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.pubmedcentral.nih.gov/art...?artid=1777777

    Antiemetic efficacy of nabilone and alizapride
    http://www.cannabis-med.org/studies/...w.php?s_id=127

    Nabilone versus domperidone
    http://www.cannabis-med.org/studies/...w.php?s_id=129

    THC or Compazine for the cancer chemotherapy patient
    http://www.cannabis-med.org/studies/...ow.php?s_id=34

    Comparison of nabilone and prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=128

    Nabilone vs. prochlorperazine for refractory emesis
    http://www.cannabis-med.org/studies/...w.php?s_id=146

    Nabilone vs. placebo
    http://www.cannabis-med.org/studies/...w.php?s_id=156

    Tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics.
    http://www.cannabis-med.org/studies/...ow.php?s_id=30

    Comparative trial of the antiemetic effects of THC and haloperidol
    http://www.cannabis-med.org/studies/...ow.php?s_id=64

    Comparison of delta-9-tetrahydrocannabinol and prochlorperazine
    http://www.cannabis-med.org/studies/...how.php?s_id=3

    Delta 9-tetrahydrocannabinol in cancer chemotherapy.
    http://www.cannabis-med.org/studies/...ow.php?s_id=88

    Antiemetic effect of tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...how.php?s_id=6

    Tetrahydrocanabinol versus metoclopramide and thiethylperazine
    http://www.cannabis-med.org/studies/...ow.php?s_id=24

    Effects of nabilone and prochlorperazine on chemotherapy-induced emesis
    http://www.cannabis-med.org/studies/...w.php?s_id=131

    Delta-9-tetrahydrocannabinol as an antiemetic
    http://www.cannabis-med.org/studies/...how.php?s_id=5

    Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
    http://www.cannabis-med.org/studies/...ow.php?s_id=23

    THC as an antiemetic in patients treated with cancer chemotherapy
    http://www.cannabis-med.org/studies/...ow.php?s_id=27

    Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC
    http://www.cannabis-med.org/studies/...w.php?s_id=107

    Superiority of nabilone over prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=126

    Antiemetic effect of delta-9-tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...how.php?s_id=4

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
    http://www.medmjscience.org/Pages/science/pierson.html

    Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
    http://www.medmjscience.org/Pages/science/chang.html

    CHILDREN/ YOUNG ADULTS

    Experiences with THC-treatment in children and adolescents
    http://www.cannabis-med.org/studies/...ow.php?s_id=80

    An efficient new cannabinoid antiemetic in pediatric oncology.
    http://www.cannabis-med.org/studies/...how.php?s_id=7

    Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
    http://www.cannabis-med.org/studies/...w.php?s_id=120

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=123

    Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD
    http://www.onlinepot.org/medical/add&mmj.htm

    Oily fish makes 'babies brainier'
    http://news.bbc.co.uk/2/hi/health/4631006.stm

    Cannabis is a First-Line Treatment for Childhood Mental Disorders
    http://www.counterpunch.org/mikuriya07082006.html

    Ganja use among Jamaican women.
    http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

    Dreher's Jamaican Pregnancy Study
    http://www.november.org/stayinfo/bre...eherStudy.html

    Cannabis Relieves Morning Sickness
    http://ccrmg.org/journal/06spr/dreher.html#morning

    Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

    Moderate cannabis use not harmful to the brain of adolescents, M R I study finds
    http://www.cannabis-med.org/english/...l.php?id=218#3

    No brain structural change associated with adolescent cannabis use
    http://www.pubmedcentral.nih.gov/art...?artid=1524733

    No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
    http://www.sciencedaily.com/releases...1204123422.htm

    Pot May Not Shrink Teens' Brains After All
    http://www.medpagetoday.com/Neurolog...rology/tb/3242

    Swiss Study Finds Marijuana Use Alone May Benefit Some Teens
    http://www.foxnews.com/story/0,2933,308258,00.html

    Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
    http://marijuana.researchtoday.net/a.../4/11/1483.htm

    Marijuana Use by Young People: The Impact of State Medical Marijuana Laws
    http://www.mpp.org/research/teen-use-report.html

    Recipe For Trouble (anecdotal)
    http://www.cbsnews.com/stories/2002/...in503022.shtml

    The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings
    http://fampra.oxfordjournals.org/cgi...bstract/cmn049

    Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
    http://www.cannabis-med.org/studies/...ttern=EPILEPSY

    The Mental Health Risks of Adolescent Cannabis Use
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CHRONIC CYSTITIS

    Cannabinoid rotation in a young woman with chronic cystitis
    http://www.cannabis-med.org/studies/...w.php?s_id=115

    COGNATIVE EFFECTS- see IQ

    COUGH

    Cannabis Cough Cure
    http://www.thehempire.com/index.php/...bis_cough_cure

    Novel treatment for cough (Patent)
    http://appft1.uspto.gov/netacgi/nph-...DN/20060013777

    CPOD

    THC effective in appetite and weight loss in severe lung disease (COPD)
    http://www.cannabis-med.org/english/...l.php?id=191#2

    Heavy Long-Term Marijuana Use Does Not Impair Lung Function
    http://www.erowid.org/plants/cannabi...s_media7.shtml

    Researchers to test if cannabis ingredient can help COPD patients
    http://www.thehempire.com/index.php/..._copd_patients

    Heavy Habitual Marijuana Smoking Does Not Cause an Accelerated Decline in FEV with Age
    http://www.ukcia.org/research/Marjiu...lineInFEV1.pdf

    CROHN'S/IBS/ULCERATIVE COLITIS

    Cannabis-based drugs could offer new hope for inflammatory bowel disease patients
    http://www.medicalnewstoday.com/articles/28584.php

    Cannabis may soothe inflamed bowels
    http://www.chanvre-info.ch/info/en/C...-inflamed.html

    In the Human Colon: Cannabinoids Promote Epithelial Wound Healing
    http://www.gastrojournal.org/article...09297/abstract

    Crohn's Patients Report Symptomatic Relief From Cannabis
    http://www.thehempire.com/index.php/cannabis/news/4650

    Cannabis Helps Ulcers And Crohn's Disease
    http://www.thehempire.com/index.php/...crohns_disease

    Bowel Study Backs Cannabis Drugs
    http://www.thehempire.com/index.php/...cannabis_drugs

    Cannabis use by patients with inflammatory bowel disease
    http://www.sciencedirect.com/science...dcc522e0951943

    Endocannabinoids and the gastrointestinal tract: what are the key questions?
    http://www.nature.com/bjp/journal/v1.../0707422a.html

    MARIJUANA AND IRRITABLE BOWEL SYNDROME (IBS) (anecdotal)
    http://www.rxmarihuana.com/christine.htm

    Marijuana and Crohn’s Disease (anecdotal)
    http://www.rxmarihuana.com/chrohns3.htm

    Mayo Study: Marijuana's THC Reduces Stomach Cramping
    http://bbsnews.net/article.php/20061029211046523

    Anti-inflammatory compound from cannabis found in herbs
    http://www.rsc.org/chemistryworld/Ne...e/24060801.asp

    Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
    http://marijuana.researchtoday.net/archive/5/6/1797.htm

    Cannabinoids and gastrointestinal motility: animal and human studies.
    http://www.unboundmedicine.com/medli...human_studies_

    Cannabinoids and intestinal motility: welcome to CB2 receptors
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    The endogenous cannabinoid system protects against colonic inflammation
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Intestinal obstruction by an unusual foreign body
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CRUETZFELDT-JACOB DISEASE- see MAD COW DISEASE

    DEPRESSION

    Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant
    http://www.jci.org/cgi/content/full/115/11/3104

    Antidepressant-like activity by blockade of anandamide hydrolysis
    http://www.pubmedcentral.nih.gov/art...medid=16352709

    Decreased depression in marijuana users. (may need free registration)
    http://www.medscape.com/medline/abstract/15964704


    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    Nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Cannabis and Depression
    http://www.pacifier.com/~alive/cmu/d...d_cannabis.htm

    Association between cannabis use and depression may not be causal, study says
    http://www.cannabis-med.org/english/...l.php?id=177#4

    Marijuana use and depression among adults: Testing for causal associations.
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Do patients use marijuana as an antidepressant?
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Cannabis' Acts as Antidepressant
    http://www.thehempire.com/index.php/...antidepressant

    Cannabis And Depression Research
    http://www.thehempire.com/index.php/...ssion_research

    Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons
    http://marijuana.researchtoday.net/a.../4/10/1460.htm

    Marijuana chemical may treat depression
    http://www.healthcentral.com/depress...193323-66.html

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Treating depression with cannabinoids
    http://www.cannabis-med.org/english/nav/home-jcant.htm

    Animal research highlights a therapeutic potential of cannabinoids for the treatment of depression
    http://www.cannabis-med.org/english/..._2008_02_1.pdf

    DERMATITIS

    Efficacy of dietary hempseed oil in patients with atopic dermatitis. (may need free registration)
    http://www.medscape.com/medline/abst...yText=hempseed

    Role seen for cannabis in helping to alleviate allergic skin disease
    http://www.physorg.com/news106487623.html

    Marijuana Might Help Cure Allergic Contact Dermatitis (a.k.a. Poison Ivy)
    http://www.healthcentral.com/skin-ca...ure-aka-ivy/1/

    Substances Similar To The Body's Own 'Cannabis (Marijuana) Are Necessary For Healthy Skin And May Lead To New Skin Disease Treatments
    http://www.medicalnewstoday.com/articles/113812.php

    DIABETES

    Cannabinoid Reduces Incidence Of Diabetes
    http://www.norml.org/index.cfm?Group_ID=6909

    Marijuana Compound May Help Stop Diabetic Retinopathy
    http://www.sciencedaily.com/releases...0227184647.htm

    Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
    http://safeaccess.ca/research/diabetes.htm

    Anticoagulant Effects of a Cannabis Extract in an Obese Rat Model
    http://www.level1diet.com/research/id/14687

    Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol
    http://ajp.amjpathol.org/cgi/content/full/168/1/235

    The Cannabinergic System as a Target for Anti-inflammatory Therapies
    http://www.ingentaconnect.com/conten...00013/art00008

    Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes
    http://www.unboundmedicine.com/medli..._diabetic_rats

    Cannabidiol reduces the development of diabetes in an animal study
    http://www.cannabis-med.org/english/...l.php?id=219#3

    Getting Eye On Cannabinoids
    http://www.thehempire.com/index.php/...n_cannabinoids

    Marijuana compound could prevent eye damage in diabetics
    http://www.thehempire.com/index.php/...e_in_diabetics

    The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice
    http://www.uccs.edu/~rmelamed/Evolut...e_disease.html

    Cannabidiol arrests onset of autoimmune diabetes in NOD mice
    http://safeaccess.ca/research/diabetes.htm

    #Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    DRIVING AND CANNABIS

    Abstracts of several studies
    http://www.ukcia.org/research/medline/8.htm

    Cannabis and driving
    http://www.ukcia.org/research/driving4.html

    CANNABIS AND ROAD SAFETY
    http://www.ukcia.org/research/driving2.htm

    Marijuana And Actual Driving Performance
    http://www.ukcia.org/research/driving.htm

    Cannabis and Driving: A Scientific and Rational Review
    http://norml.org/index.cfm?Group_ID=7459

    Fitness to drive in spite (because) of THC
    http://www.unboundmedicine.com/medli...use__of_THC%5D

    DRONABINOL also see MARINOL

    GENERIC NAME: DRONABINOL - ORAL (dro-NAB-in-all)
    BRAND NAME(S): Marinol
    http://www.medicinenet.com/dronabinol-oral/article.html


    Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    Dronabinol in the treatment of refractory agitation in Alzheimer’s disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=92

    Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
    http://www.cannabis-med.org/studies/...ow.php?s_id=59

    Dronabinol an effective appetite stimulant?
    http://www.cannabis-med.org/studies/...w.php?s_id=188

    Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    Effect of dronabinol on nutritional status in HIV infection.
    http://www.cannabis-med.org/studies/...w.php?s_id=150

    Dronabinol stimulates appetite and causes weight gain in HIV patients.
    http://www.cannabis-med.org/studies/...ow.php?s_id=20

    Dronabinol effects on weight in patients with HIV infection.
    http://www.cannabis-med.org/studies/...ow.php?s_id=45

    Recent clinical experience with dronabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=90

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
    http://www.cannabis-med.org/studies/...w.php?s_id=180

    Dronabinol and prochlorperazine in combination
    http://www.cannabis-med.org/studies/...ow.php?s_id=28

    Dronabinol enhancement of appetite in cancer patients.
    http://www.cannabis-med.org/studies/...w.php?s_id=149

    Efficacy of dronabinol alone and in combination
    http://www.cannabis-med.org/studies/...w.php?s_id=191

    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    Dronabinol and retinal hemodynamics in humans.
    http://www.cannabis-med.org/studies/...w.php?s_id=202

    Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
    http://www.cannabis-med.org/studies/...w.php?s_id=181

    Nausea relieved by tetrahydrocannabinol (dronabinol).
    http://www.cannabis-med.org/studies/...ow.php?s_id=35

    Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
    http://www.cannabis-med.org/studies/...w.php?s_id=116

    Treatment of spasticity in spinal cord injury with dronabinol
    http://www.cannabis-med.org/studies/...w.php?s_id=112

    Cannabinoid Activator Mellows Out Colon
    http://www.medpagetoday.com/MeetingCoverage/ACG/tb/4410

    Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
    http://marijuana.researchtoday.net/archive/4/8/1234.htm

    Mayo Study: Marijuana's THC Reduces Stomach Cramping
    http://bbsnews.net/article.php/20061029211046523

    Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol
    http://ajp.psychiatryonline.org/cgi/...full/165/4/536

    DRUG INTERACTIONS- see INTERACTIONS WITH OTHER DRUGS

    DRUG TESTING

    Hemp oil causes positive urine tests for THC
    http://www.druglibrary.org/crl/drugt...JAnToxicol.pdf

    Deposition of cannabinoids in hair after long-term use of cannabis
    http://marijuana.researchtoday.net/archive/4/7/1002.htm

    Cannabinoid concentrations in hair from documented cannabis users.
    http://marijuana.researchtoday.net/archive/4/6/924.htm

    Detection time of regular THC use in urine shorter than often assumed
    http://www.acmed.org/english/bulleti...l.php?id=213#2

    Differentiation between drug use and environmental contamination when testing for drugs in hair
    http://www.sciencedirect.com/science...ad1bd10fb041bf

    The effects of adulterants and selected ingested compounds on drugs-of-abuse testing in urine.
    http://marijuana.researchtoday.net/archive/4/8/1389.htm

    Toxicity From the Use of Niacin to Beat Urine Drug Screening
    http://www.sciencedirect.com/science...9d8b53ea07c431

    Evaluation of the IDS One-Step™ ELISA kits for the detection of illicit drugs in hair
    http://www.sciencedirect.com/science...65bbd05717cb04

    Deposition of cannabinoids in hair after long-term use of cannabis
    http://www.sciencedirect.com/science...df7a40474cf025

    Excretion of Δ9-tetrahydrocannabinol in sweat
    http://www.sciencedirect.com/science...98c2e3fc4989d1

    Portable Oral-Fluid Tests Still Unreliable For Pot, Study Says
    http://norml.org/index.cfm?Group_ID=7636

    Current Developments in Drug Testing in Oral Fluid.
    http://www.drug-monitoring.com/pt/re...195628!8091!-1

    Drug-Test Cheats Try New Tricks on Labs
    http://www.webmd.com/mental-health/n...tricks-on-labs

    Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
    http://www.cannabis-med.org/studies/...ttern=EPILEPSY

    Marijuana Use More Prevalent With Epilepsy
    http://www.medscape.com/viewarticle/465891

    Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    DYSTONIA

    Cannabis sativa and dystonia secondary to Wilson's disease. (may need free registration)
    http://www.medscape.com/medline/abstract/15390041

    Experiences with THC-treatment in children and adolescents
    http://www.cannabis-med.org/studies/...ow.php?s_id=80

    Evaluation of cannabidiol in dystonic movement disorders
    http://www.cannabis-med.org/studies/...ow.php?s_id=14

    Cannabidiol in dystonic movement disorders.
    http://www.cannabis-med.org/studies/...w.php?s_id=139

    Beneficial and adverse effects of cannabidiol in a Parkinson patient
    http://www.cannabis-med.org/studies/...w.php?s_id=142

    Treatment of Meige's syndrome with cannabidiol.
    http://www.cannabis-med.org/studies/...w.php?s_id=114

    ENDOCANNABINOID DEFICIENCY

    Clinical Endocannabinoid Deficiency
    http://www.freedomtoexhale.com/clinical.pdf

    The endocannabinoid system is dysregulated in multiple sclerosis
    http://brain.oxfordjournals.org/cgi/...tract/awm160v1

    Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    http://brain.oxfordjournals.org/cgi/...ll/126/10/2191

    Migraine may be related to under production of cannabinoids
    http://www.illinoisnorml.org/index2....o_pdf=1&id=755

    Endocannabinoids: Multi-scaled, Global Homeostatic Regulators of Cells and Society
    http://knowledgetoday.org/wiki/index.php/ICCS06/70

    EPILEPSY

    Epilepsy patients are smoking pot
    http://www.safeaccessnow.org/article.php?id=1638

    Experiences with THC-treatment in children and adolescents
    http://www.cannabis-med.org/studies/...ow.php?s_id=80

    Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
    http://www.cannabis-med.org/studies/...ow.php?s_id=42

    Anticonvulsant nature of marihuana smoking.
    http://www.cannabis-med.org/studies/...ow.php?s_id=39

    Cannabis may help epileptics
    http://www.medicalnewstoday.com/articles/4423.php

    Hypnotic and Antiepileptic Effects of Cannabidiol
    http://www.thecompassionclub.org/med...ue&pageNumber=

    Marijuana: an effective antiepileptic treatment in partial epilepsy?
    http://www.cannabis-med.org/studies/...w.php?s_id=157

    Marijuana and Epilepsy (anecdotal)
    http://www.rxmarihuana.com/epilepsy.htm

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
    http://www.cannabis-med.org/studies/...ttern=EPILEPSY

    Marijuana Use More Prevalent With Epilepsy
    http://www.medscape.com/viewarticle/465891

    Endocannabinoids and Their Implications for Epilepsy
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    FAMILIAL MEDITERRANEAN FEVER

    Pain relief with oral cannabinoids in familial Mediterranean fever.
    http://www.cannabis-med.org/studies/...ow.php?s_id=18

    FERTILITY

    Synthetic Cannabinoid May Aid Fertility In Smokers
    http://www.medicalnewstoday.com/articles/58063.php

    FEVER

    A Novel Role of Cannabinoids
    http://jpet.aspetjournals.org/cgi/co...ull/320/3/1127

    A Cooling Effect From Cannabis?
    http://ccrmg.org/journal/05aut/coolcannabis.html

    Marijuana Might Really Make You Cool
    http://www.thehempire.com/index.php/..._make_you_cool

    FIBROMYALGIA

    Delta-9-THC based monotherapy in fibromyalgia patients
    http://www.immunesupport.com/library...293&t=CFIDS_FM

    Clinical Endocannabinoid Deficiency
    http://www.freedomtoexhale.com/clinical.pdf

    Cannabis Sativa (Marijuana) for Fibromyalgia
    http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm

    THC Reduces Pain in Fibromyalgia Patients
    http://www.illinoisnorml.org/content/view/63/35/

    Fibromyalgia: Effective Treatment with Medical Marijuana
    http://www.salem-news.com/articles/n...gia_112807.php

    Cannabis Science: Nabilone reduced chronic pain caused by fibromyalgia
    http://bbsnews.net/article.php/20071111150357312

    Fibromyalgia and Medical Marijuana
    http://www.webmd.com/fibromyalgia/gu...ical-marijuana

    Nabilone for the treatment of pain in fibromyalgia.
    http://www.ncbi.nlm.nih.gov/pubmed/17974490

    GASTRIC BYPASS

    THC effective in intractable nausea in a patient undergoing gastric bypass surgery
    http://bbsnews.net/article.php/2008020313112065

    GATEWAY THEORY

    The Myth of Marijuana's Gateway Effect
    http://www.druglibrary.org/schaffer/library/mjgate.htm

    Endogenous cannabinoids are not involved in cocaine reinforcement
    http://www.sciencedirect.com/science...4e861a90579fac

    No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
    http://www.sciencedaily.com/releases...1204123422.htm

    CLAIM #13:MARIJUANA IS A "GATEWAY" TO THE USE OF OTHER DRUGS
    http://www.erowid.org/plants/cannabi...s_myth13.shtml

    Gateway To Nowhere? The Evidence That Pot Doesn't Lead To Heroin
    http://www.thehempire.com/index.php/...lead_to_heroin

    Cannabis use when it's legal
    http://www.sciencedirect.com/science...96c8de7949a364

    Cannabis Use- A Gateway to other Drugs? The Case of Amsterdam
    http://www.ukcia.org/research/Cannab...ppingStone.pdf

    Twin study fails to prove 'gateway' hypothesis
    http://www.ukcia.org/research/Escala...veGateway.html

    GLAUCOMA/ VISION

    Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
    http://archopht.ama-assn.org/cgi/con...ct/116/11/1433

    Dronabinol and retinal hemodynamics in humans.
    http://www.cannabis-med.org/studies/...w.php?s_id=202

    Effect of Sublingual Application of Cannabinoids on Intraocular Pressure
    http://www.cannabis-med.org/studies/...w.php?s_id=201

    Delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.
    http://www.cannabis-med.org/studies/...ow.php?s_id=88

    Effect of marihuana on intraocular and blood pressure in glaucoma.
    http://www.cannabis-med.org/studies/...ow.php?s_id=87

    Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans.
    http://www.cannabis-med.org/studies/...ow.php?s_id=40

    Marihuana smoking and intraocular pressure.
    http://www.cannabis-med.org/studies/...ow.php?s_id=47

    Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-Tetrahydrocannabinol
    http://www.unboundmedicine.com/medli...el_of_Glaucoma

    Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
    http://www.unboundmedicine.com/medli..._peroxynitrite

    Effects of tetrahydrocannabinol on arterial and intraocular hypertension.
    (may need free registration)
    http://www.medscape.com/medline/abstract/468444

    Cannabis improves night vision:
    http://www.sciencedirect.com/science...d0a198efd77cb6

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma
    http://www.patentstorm.us/patents/4189491.html

    Reduction of Congenital Nystagmus in a Patient after Smoking Cannabis.
    http://www.unboundmedicine.com/medli...king_Cannabis_

    Cannabinoids and glaucoma
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    CONJUGATE DEVIATION OF THE EYES AFTER Cannabis indica INTOXICATION*
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    GYNOCOLOGY AND OBSTETRICS

    Cannabis Treatments in Obstetrics and Gynecology: A Historical Review
    http://www.freedomtoexhale.com/russo-ob.pdf

    HEADACHE- see MIGRAINE

    HEART DISEASE/ CARDIOVASCULAR

    Marijuana Chemical Fights Hardened Arteries
    http://www.webmd.com/heart-disease/n...dened-arteries

    The endogenous cardiac cannabinoid system: a new protective mechanism
    http://www.ncbi.nlm.nih.gov/pubmed/16618028

    Cardiovascular pharmacology of cannabinoids.
    http://www.biowizard.com/story.php?pmid=16596789

    Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia
    http://www.ingentaconnect.com/conten...20001/00002346

    Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
    http://www.medscape.com/viewarticle/525040_print

    Cannabinoid Offers Cardioprotection
    http://www.norml.org/index.cfm?Group...m_format=pri nt

    Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks
    http://www.norml.org/index.cfm?Group_ID=6972

    Marijuana use, diet, body mass index, and cardiovascular risk factors (may need free registration)
    http://www.medscape.com/medline/abstract/16893701

    Cannabinoids and cardiovascular disease
    http://www.unboundmedicine.com/medli...cal_treatments

    Cannabinoids as therapeutic agents in cardiovascular disease
    http://www.unboundmedicine.com/medli..._and_illusions

    The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol
    http://www.unboundmedicine.com/medli...oxide_synthase

    Cannabinoids prevented the development of heart failure in animal study
    http://www.cannabis-med.org/english/...l.php?id=145#2

    Cannabis use not associated with risk factors for diseases of heart and circulation
    http://www.cannabis-med.org/english/...l.php?id=225#2

    THC protects heart cells in the case of lowered oxygen supply
    http://www.cannabis-med.org/english/...l.php?id=212#1

    Medical marijuana: study shows that THC slows atherosclerosis
    http://thenexthurrah.typepad.com/the...l_marijua.html

    Cardiovascular Effects of Cannabis
    http://www.idmu.co.uk/canncardio.htm

    Changes in middle cerebral artery velocity after marijuana
    http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract

    Cannabidiol protects against myocardial ischemic reperfusion injury.
    http://marijuana.researchtoday.net/a.../4/12/1404.htm

    Function of cannabinoids in heart failure]
    http://www.unboundmedicine.com/medli...art_failure%5D

    Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez



    HEPATITIS

    Moderate Cannabis Use Associated with Improved Treatment Response
    http://www.hivandhepatitis.com/hep_c.../091506_a.html

    Cannabis use improves retention and virological outcomes in patients treated for hepatitis C
    http://www.natap.org/2006/HCV/091506_02.htm

    Hepatitis C - The Silent Killer Can Medical Cannabis Help?
    http://www.pacifier.com/~alive/cmu/hepatitis_c.htm

    Study: Pot Helps Hepatitis Treatment
    http://www.thehempire.com/index.php/...itis_treatment

    Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids
    http://molpharm.aspetjournals.org/cg...stract/74/1/20

    Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus.
    http://www.cannabis-med.org/studies/...w.php?s_id=165

    HERPES

    Cannabis May Help Combat Cancer-causing Herpes Viruses
    http://www.sciencedaily.com/releases...0923092627.htm

    THC inhibits lytic replication of gamma oncogenic herpes viruses in vitro
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Suppressive effect of delta-9-tetrahydrocannabinol on herpes simplex virus infectivity in vitro
    http://www.ebmonline.org/cgi/content/abstract/196/4/401

    Inhibition of cell-associated herpes simplex virus
    http://www.ebmonline.org/cgi/content/abstract/185/1/41

    The Effect of {Delta}-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication
    http://vir.sgmjournals.org/cgi/conte...tract/49/2/427

    HICCUPS

    Marijuana cures hiccups
    http://www.yourhealthbase.com/database/a77k.htm

    Marijuana For Intractable Hiccups
    http://cannabislink.ca/medical/hiccups.html

    HISTORICAL STUDIES


    The La Guardia Committee Report
    http://www.druglibrary.org/schaffer/...ag/lagmenu.htm

    Physical, Mental, and Moral Effects of Marijuana: The Indian Hemp Drugs Commission Report
    http://www.druglibrary.org/schaffer/Library/effects.htm

    MARIAJUANA SMOKING IN PANAMA
    http://www.druglibrary.org/schaffer/...ma/panama1.htm

    The British Pharmaceutical Codex – 1934
    http://www.druglibrary.org/schaffer/...cal/brit34.htm

    ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH
    http://www.druglibrary.org/schaffer/...850/gunjah.htm

    DISPENSATORY OF THE UNITED STATES OF AMERICA Fifth Edition (1843)
    http://www.druglibrary.org/schaffer/...y/dispensa.htm

    New Remedies:pharmaceutically and Therapeutically Considered Fourth Edition (1843)
    http://www.druglibrary.org/schaffer/...y/dunglisn.htm

    On the Haschisch or Cannabis Indica
    http://www.druglibrary.org/schaffer/...y/bellhash.htm

    ON INDICATIONS OF THE HACHISH-VICE IN THE OLD TESTAMENT
    http://www.druglibrary.org/schaffer/...ory/hashot.htm

    The Physiological Activity of Cannabis Sativa
    http://www.druglibrary.org/schaffer/...story/japa.htm

    CANNABIS, U.S.P. (American Cannabis):
    http://www.druglibrary.org/schaffer/...y/vbchmed1.htm

    History of Cannabis and Its Preparations in Saga, Science and Sobriquethttp://www3.interscience.wiley.com/c...06128/PDFSTART

    Observations on the medicinal properties of the Cannabis Sativa of India
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabis Sativa Seu Indica: Indian Hemp
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Collapse after intravenous injection of hashish. (1968)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Adverse Effects of Intravenous Cannabis Tea (1977)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Paraquat and marijuana: epidemiologic risk assessment. (1978)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Hashish and drug abuse in Egypt during the 19th and 20th centuries.
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Marihuana and drug abuse. Recommendations of the Committee on Public Health, New York Academy of Medicine. (1973)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Observations on the Cannabis Indica, or Indian Hemp (1843)
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    A Case of Dysmenorrhœa in Which the Tincture of Cannabis Indica Was Employed, with Some Observations upon That Drug
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    HIV / AIDS

    Marijuana Use Does Not Accelerate HIV Infection
    http://paktribune.com/news/print.php?id=139255

    THC improves appetite and reverses weight loss in AIDS patients
    http://www.cannabis-med.org/studies/...w.php?s_id=189

    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    Cannabis in painful HIV-associated sensory neuropathy
    http://www.cannabis-med.org/studies/...w.php?s_id=199

    Smoked cannabis therapy for HIV-related painful peripheral neuropathy
    http://www.cannabis-med.org/studies/...w.php?s_id=172

    Short-term effects of cannabinoids in patients with HIV-1 infection
    http://www.cannabis-med.org/studies/...ow.php?s_id=62

    Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.
    http://www.cannabis-med.org/studies/...ow.php?s_id=21

    Effect of dronabinol on nutritional status in HIV infection.
    http://www.cannabis-med.org/studies/...w.php?s_id=150

    Dronabinol stimulates appetite and causes weight gain in HIV patients.
    http://www.cannabis-med.org/studies/...ow.php?s_id=20

    Dronabinol effects on weight in patients with HIV infection.
    http://www.cannabis-med.org/studies/...ow.php?s_id=45

    Recent clinical experience with dronabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=90

    Marijuana as therapy for people living with HIV/AIDS: Social and health aspects
    http://www.unboundmedicine.com/medli...health_aspects

    Marijuana and AIDS: A Four-Year Study
    http://ccrmg.org/journal/05spr/aids.html

    Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
    http://marijuana.researchtoday.net/archive/4/8/1234.htm

    Cannabis: Use in HIV for Pain and Other Medical Symptoms
    http://www.sciencedirect.com/science...ca04d8bd433c52

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Denbinobin... inhibits HIV-1 replication through an NF-kappaB-dependent pathway.
    http://marijuana.researchtoday.net/a.../5/10/2003.htm

    HORMONES

    Effects of chronic marijuana use on testosterone, luteinizing hormone, follicle stimulating hormone, prolactin and cortisol in men and women.
    http://www.ncbi.nlm.nih.gov/pubmed/1935564

    Marijuana: interaction with the estrogen receptor
    http://jpet.aspetjournals.org/cgi/co...ract/224/2/404

    Endocrine Effects of Marijuana
    http://www.ukcia.org/research/EndocrineEffects.pdf


    HUNTINGTON'S DISEASE

    EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE
    http://www.druglibrary.org/schaffer/...l/hunting1.htm

    Nabilone Could Treat Chorea and Irritability in Huntington’s Disease
    http://neuro.psychiatryonline.org/cg...18/4/553?rss=1


    HYSTERECTOMY

    Effect of nabilone on nausea and vomiting after total abdominal hysterectomy
    http://www.cannabis-med.org/studies/...w.php?s_id=137

    IBS- see CROHN'S

    IDIOPATHIC INTRACRANIAL HYPERTENSION

    Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
    http://www.cannabis-med.org/studies/...w.php?s_id=181

    INTERACTIONS WITH OTHER DRUGS

    Efficacy of dronabinol alone and in combination
    http://www.cannabis-med.org/studies/...w.php?s_id=191

    Dronabinol and prochlorperazine in combination
    http://www.cannabis-med.org/studies/...ow.php?s_id=28

    Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect
    http://www.medjournal.com/forum/show...87&postcount=1

    Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=197

    Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.
    http://www.cannabis-med.org/studies/...w.php?s_id=178

    The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
    http://www.cannabis-med.org/studies/...ow.php?s_id=17

    Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
    http://www.unboundmedicine.com/medli..._arthritic_rat

    Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.
    http://www.cannabis-med.org/studies/...w.php?s_id=148

    Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel.
    http://www.cannabis-med.org/studies/...rn=INTERACTION

    IQ/ MEMORY/ COGNITIVE EFFECTS

    Findings of a longitudinal study of effects on IQ
    http://www.cmaj.ca/cgi/content/full/166/7/887

    Heavy cannabis use without long-term effect on global intelligence
    http://www.cannabis-med.org/english/...l.php?id=115#2

    Marijuana does not dent IQ permanently
    http://www.newscientist.com/article/...rmanently.html

    Cannabis use and cognitive decline in persons under 65 years of age
    http://www.ukcia.org/research/Cannab...veDecline.html

    Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats

    http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

    Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
    http://www.unboundmedicine.com/medli...annabis_users_

    Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study.
    http://www.ncbi.nlm.nih.gov/pubmed/12901774

    Review: executive functioning and cannabis use.
    http://www.unboundmedicine.com/medli...nnabis_use_%5D

    Neuropsychological effects of marijuana
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    LONG TERM USE EFFECTS

    Long-Term Marijuana Users Suffer Few Health Problems, Australian Study Indicates
    http://www.ukcia.org/research/aus.htm

    Neuropsychological Performance in Long-term Cannabis Users
    http://www.ukcia.org/research/Neurop...nabisUsers.htm

    Long term marijuana users seeking medical cannabis in California
    http://www.harmreductionjournal.com/content/4/1/16

    LUPUS

    Cannabis May Suppress Immune System
    http://lupus.webmd.com/news/20030415...-immune-system

    Systemic Lupus by Dawn (anecdotal)
    http://www.erowid.org/experiences/exp.php?ID=49481

    MAD COW/ CRUETZFELDT-JACOB DISEASE

    Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity
    http://www.jneurosci.org/cgi/content...act/27/36/9537

    Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
    http://bbsnews.net/article.php/20070916110536662

    MARINOL/ SYNTHETICS/ CANNABINOID MIXTURES

    CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
    http://www.druglibrary.org/schaffer/hemp/migrn2.htm

    Marinol vs Natural Cannabis
    http://www.norml.org/pdf_files/NORML...l_Cannabis.pdf

    The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.
    (may need free registration)
    http://www.medscape.com/medline/abstract/16209908

    Unheated Cannabis sativa extracts and its major compound THC-acid
    http://www.ncbi.nlm.nih.gov/pubmed/16504929

    Side effects of pharmaceuticals not elicited by comparable herbal medicines.
    http://content.herbalgram.org/youngl...ew.asp?i=41444

    Sativex in the treatment of pain caused by rheumatoid arthritis
    http://rheumatology.oxfordjournals.o. ..stract/45/1/50

    Is dronabinol an effective appetite stimulant?
    http://www.cannabis-med.org/studies/...w.php?s_id=188

    Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
    http://www.cannabis-med.org/studies/...w.php?s_id=168

    Sativex® in patients with symptoms of spasticity due to multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=169

    Nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
    http://www.cannabis-med.org/studies/...w.php?s_id=180

    Synthetic cannabinomimetic nabilone on patients with chronic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=197

    Nabilone significantly reduces spasticity-related pain
    http://www.cannabis-med.org/studies/...w.php?s_id=200

    Sativex produced significant improvements in a subjective measure of spasticity
    http://www.cannabis-med.org/studies/...w.php?s_id=170

    Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain
    http://www.cannabis-med.org/studies/...ow.php?s_id=85

    Cannabinoid rotation in a young woman with chronic cystitis
    http://www.cannabis-med.org/studies/...w.php?s_id=115

    Dronabinol in patients with intractable pruritus
    http://www.cannabis-med.org/studies/...w.php?s_id=116

    Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease:
    http://www.cannabis-med.org/studies/...ow.php?s_id=54

    Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
    http://www.cannabis-med.org/studies/...w.php?s_id=153

    Nabilone in the treatment of multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=11

    Big Pharma's Strange Holy Grail: Cannabis Without Euphoria?
    http://www.counterpunch.org/gardner07082006.html

    Sativex showed positive effects in 65 per cent of patients with chronic diseases
    http://www.cannabis-med.org/english/...l.php?id=230#4

    Medical use of cannabinoids does not cause an increase in serious adverse health effects
    http://www.cmaj.ca/cgi/content/full/178/13/1685

    MEIGE'S SYNDROME

    Treatment of Meige's syndrome with cannabidiol.
    http://www.cannabis-med.org/studies/...w.php?s_id=114

    MEMORY- see IQ

    MENTAL DISORDERS- see SCHIZOPHRENIA

    IGRAINE/ HEADACHE

    CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
    http://www.druglibrary.org/schaffer/hemp/migrn2.htm

    Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
    http://www.cannabis-med.org/studies/...w.php?s_id=181

    Cannabis and Migraine
    http://www.pacifier.com/~alive/cmu/c...d_migraine.htm

    Clinical Endocannabinoid Deficiency
    http://www.freedomtoexhale.com/clinical.pdf

    Hemp for Headache
    http://www.freedomtoexhale.com/hh.pdf

    Chronic Migraine Headache
    http://www.druglibrary.org/schaffer/hemp/migrn1.htm

    Cannabis for Migraine Treatment: Once and Future Treatment?
    http://www.druglibrary.org/crl/pain/...ne_%20Pain.pdf

    Cannabinoids block release of serotonin from platelets induced by plasma from migraine patients
    http://www.ukcia.org/research/Cannab...Platelets.html

    Migraine may be related to under production of cannabinoids
    http://www.illinoisnorml.org/index2....o_pdf=1&id=755

    Cluster Attacks Responsive to Recreational Cannabis and Dronabinol.
    http://www.ncbi.nlm.nih.gov/pubmed/1...Pubmed_RVBrief

    Inhaled Cannabis Aborts Cluster Headaches, Journal Reports
    http://norml.org/index.cfm?Group_ID=7817

    MORNING SICKNESS

    Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

    Medicinal cannabis use among childbearing women
    http://safeaccess.ca/research/cannabis_nausea2006.pdf

    Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
    http://haworthpress.com/store/Articl...t.asp?ID=18139

    MORTALITY RATES

    Marijuana use and mortality.
    http://www.pubmedcentral.nih.gov/art...?artid=1380837

    Marijuana Smoking Doesn't Lead to Higher Death Rate
    http://ccrmg.org/journal/03sum/kaiser.html

    How deadly is marijuana?
    http://www.medicalnewstoday.com/articles/4426.php

    MS/ MULTIPLE SCLEROSIS

    Sativex in patients with symptoms of spasticity due to multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=169

    Marijuana derivatives may provide MS treatment
    http://www.health.am/ab/more/marijua..._ms_treatment/

    Marijuana Helps MS Patients Alleviate Pain, Spasms
    http://www.mult-sclerosis.org/news/S...msAndPain.html

    Cannabis-based medicine in central pain in multiple sclerosis
    http://www.neurology.org/cgi/content.../65/6/812?etoc

    Cannabis-based medicine in spasticity caused by multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=192

    Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
    http://www.cannabis-med.org/studies/...w.php?s_id=168

    The effect of cannabis on urge incontinence in patients with multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=185

    Nabilone significantly reduces spasticity-related pain
    http://www.cannabis-med.org/studies/...w.php?s_id=200

    Cannabinoids in multiple sclerosis (CAMS) study
    http://www.cannabis-med.org/studies/...w.php?s_id=160

    Sativex produced significant improvements in a subjective measure of spasticity
    http://www.cannabis-med.org/studies/...w.php?s_id=170

    Cannabis-based medicine in central pain in multiple sclerosis.
    http://www.cannabis-med.org/studies/...w.php?s_id=175

    Do cannabis-based medicinal extracts have general or specific effects
    http://www.cannabis-med.org/studies/...ow.php?s_id=56

    Efficacy, safety and tolerability of an oral cannabis extract in the treatment of spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=63

    Cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=81

    Are oral cannabinoids safe and effective in refractory neuropathic pain?
    http://www.cannabis-med.org/studies/...w.php?s_id=143

    Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    Cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=82

    Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=108

    Cannabis based medicinal extract on refractory lower urinary tract dysfunction
    http://www.cannabis-med.org/studies/...w.php?s_id=103

    Analgesic effect of the cannabinoid analogue nabilone
    http://www.cannabis-med.org/studies/...w.php?s_id=203

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    Nabilone in the treatment of multiple sclerosis
    http://www.cannabis-med.org/studies/...ow.php?s_id=11

    Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.
    http://www.cannabis-med.org/studies/...how.php?s_id=2

    Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.
    http://www.cannabis-med.org/studies/...how.php?s_id=1

    Tetrahydrocannabinol for tremor in multiple sclerosis.
    http://www.cannabis-med.org/studies/...how.php?s_id=9

    Marihuana as a therapeutic agent for muscle spasm or spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=53

    Cannabis-based medicine in spasticity caused by multiple sclerosis.
    http://www.unboundmedicine.com/medli...iple_sclerosis

    Cannabis based treatments for neuropathic and multiple sclerosis-related pain.
    http://www.unboundmedicine.com/medli...s_related_pain

    The effect of cannabis on urge incontinence in patients with multiple sclerosis
    http://www.unboundmedicine.com/medli...al__CAMS_LUTS_

    Can Cannabis Help Multiple Sclerosis? An International Debate Rages
    http://www.pacifier.com/~alive/cmu/c...is_help_ms.htm

    Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease
    http://www.illinoisnorml.org/index2....o_pdf=1&id=104

    The endocannabinoid system is dysregulated in multiple sclerosis
    http://brain.oxfordjournals.org/cgi/...tract/awm160v1

    Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    http://brain.oxfordjournals.org/cgi/...ll/126/10/2191

    Cannabis could hold the key to ending multiple sclerosis misery
    http://www.physorg.com/news94743932.html

    Cuppa Gives A Better 'ooh'
    http://www.thehempire.com/index.php/...s_a_better_ooh

    Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    http://brain.oxfordjournals.org/cgi/...ct/126/10/2191

    Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis
    http://www.jneurosci.org/cgi/content...urcetype=HWCIT

    Cannabinoid control of neuroinflammation related to multiple sclerosis.
    http://marijuana.researchtoday.net/a.../4/10/1400.htm

    Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite
    http://www.sciencedirect.com/science...e473322a24e5bf

    The use of cannabinoids in MS: is it evidence based?
    http://www.ukcia.org/research/UseOfC...denceBased.pdf

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
    http://www.ukcia.org/research/WholeP...icSymptoms.pdf

    Emerging properties of Cannabinoid medicines in the management of MS
    http://www.ukcia.org/research/Manage...eSclerosis.pdf

    Cannabis use in Spanish patients with multiple sclerosis
    http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

    Cannabis May Halt Progression Of Multiple Sclerosis
    http://norml.org/index.cfm?Group_ID=7704

    Cannabinoid control of neuroinflammation related to multiple sclerosis
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    MRSA

    Antibacterial Cannabinoids from Cannabis sativa
    http://pubs.acs.org/cgi-bin/sample.c...np8002673.html

    Killing bacteria with cannabis
    http://arstechnica.com/journals/scie...-with-cannabis

    Chemicals in Marijuana May Fight MRSA
    http://www.webmd.com/news/20080904/m...may-fight-mrsa

    Marijuana Ingredients Show Promise In Battling Superbugs
    http://www.medicalnewstoday.com/articles/120477.php

    How pot may win the war against super-bacteria
    http://healthcare.zdnet.com/?p=1324

    New medical uses found for marijuana
    http://cannabisnews.com/news/24/thread24167.shtml

    NABILONE

    GENERIC NAME: NABILONE - ORAL (NAB-ih-lone)
    Brand Names : Cesamet
    http://www.medicinenet.com/nabilone-oral/article.htm

    The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    Nabilone versus prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=120

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=123

    Antiemetic efficacy of nabilone and alizapride
    http://www.cannabis-med.org/studies/...w.php?s_id=127

    Nabilone versus domperidone
    http://www.cannabis-med.org/studies/...w.php?s_id=129

    Comparison of nabilone and prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=128

    Nabilone vs. prochlorperazine for refractory emesis
    http://www.cannabis-med.org/studies/...w.php?s_id=146

    Nabilone vs. placebo
    http://www.cannabis-med.org/studies/...w.php?s_id=156

    Effects of nabilone and prochlorperazine on chemotherapy-induced emesis
    http://www.cannabis-med.org/studies/...w.php?s_id=131

    Superiority of nabilone over prochlorperazine
    http://www.cannabis-med.org/studies/...w.php?s_id=126

    Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
    http://www.cannabis-med.org/studies/...w.php?s_id=120

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=123

    Effect of nabilone on nausea and vomiting after total abdominal hysterectomy
    http://www.cannabis-med.org/studies/...w.php?s_id=137

    Nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    Synthetic cannabinomimetic nabilone on patients with chronic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=197

    Nabilone significantly reduces spasticity-related pain
    http://www.cannabis-med.org/studies/...w.php?s_id=200

    Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
    http://www.cannabis-med.org/studies/...w.php?s_id=153

    Nabilone in the treatment of multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=11

    Nabilone significantly reduces spasticity-related pain
    http://www.cannabis-med.org/studies/...w.php?s_id=200

    Analgesic effect of the cannabinoid analogue nabilone
    http://www.cannabis-med.org/studies/...w.php?s_id=203

    Nabilone in the treatment of multiple sclerosis
    http://www.cannabis-med.org/studies/...ow.php?s_id=11

    Comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
    http://www.cannabis-med.org/studies/...w.php?s_id=130

    Nabilone and metoclopramide in the treatment of nausea and vomiting
    http://www.cannabis-med.org/studies/...w.php?s_id=121

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=123

    Comparison of the antiemetic efficacy of nabilone and alizapride
    http://www.cannabis-med.org/studies/...w.php?s_id=127

    Nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
    http://www.cannabis-med.org/studies/...w.php?s_id=129

    Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain -
    http://www.cannabis-med.org/studies/...w.php?s_id=197

    Comparison of bronchial effects of nabilone and terbutaline
    http://www.cannabis-med.org/studies/...ow.php?s_id=43

    Nabilone Could Treat Chorea and Irritability in Huntington’s Disease
    http://neuro.psychiatryonline.org/cg...18/4/553?rss=1

    Cannabis Science: Nabilone reduced chronic pain caused by fibromyalgia
    http://bbsnews.net/article.php/20071111150357312

    Nabilone for the treatment of pain in fibromyalgia.
    http://www.ncbi.nlm.nih.gov/pubmed/17974490

    Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    NAUSEA

    THC improves appetite and reverses weight loss in AIDS patients
    http://www.cannabis-med.org/studies/...w.php?s_id=189

    Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone
    http://www.cannabis-med.org/studies/...w.php?s_id=191

    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    Nabilone improves pain and symptom management in cancer patients
    http://www.cannabis-med.org/studies/...w.php?s_id=177

    Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
    http://www.cannabis-med.org/studies/...w.php?s_id=180

    Nausea relieved by tetrahydrocannabinol (dronabinol).
    http://www.cannabis-med.org/studies/...ow.php?s_id=35

    An efficient new cannabinoid antiemetic in pediatric oncology.
    http://www.cannabis-med.org/studies/...how.php?s_id=7

    Effect of nabilone on nausea and vomiting after total abdominal hysterectomy.
    http://www.cannabis-med.org/studies/...w.php?s_id=137

    Marijuana as antiemetic medicine
    http://www.cannabis-med.org/studies/...w.php?s_id=134

    Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy
    http://www.cannabis-med.org/studies/...ow.php?s_id=31

    Inhalation marijuana as an antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=155

    Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
    http://www.cannabis-med.org/studies/...w.php?s_id=120

    Comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
    http://www.cannabis-med.org/studies/...w.php?s_id=130

    Nabilone and metoclopramide in the treatment of nausea and vomiting
    http://www.cannabis-med.org/studies/...w.php?s_id=121

    Nabilone: an alternative antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=123

    Comparison of the antiemetic efficacy of nabilone and alizapride
    http://www.cannabis-med.org/studies/...w.php?s_id=127

    Nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
    http://www.cannabis-med.org/studies/...w.php?s_id=129

    THC or Compazine for the cancer chemotherapy patient--the UCLA study
    http://www.cannabis-med.org/studies/...ow.php?s_id=34

    Comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=128

    Acute and subacute bronchial effects of oral cannabinoids.
    http://www.cannabis-med.org/studies/...ow.php?s_id=44

    Nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=146

    Nabilone vs. placebo in chemotherapy-induced nausea and vomiting.
    http://www.cannabis-med.org/studies/...w.php?s_id=156

    Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine
    http://www.cannabis-med.org/studies/...ow.php?s_id=30 delta 9-

    Comparative trial of the antiemetic effects of THC and haloperidol
    http://www.cannabis-med.org/studies/...ow.php?s_id=64

    Comparison of delta-9-tetrahydrocannabinol and prochlorperazine.
    http://www.cannabis-med.org/studies/...how.php?s_id=3

    Tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.
    http://www.cannabis-med.org/studies/...ow.php?s_id=88

    Antiemetic effect of tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...how.php?s_id=6

    The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine
    http://www.cannabis-med.org/studies/...ow.php?s_id=24

    The antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis.
    http://www.cannabis-med.org/studies/...w.php?s_id=131

    Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy
    http://www.cannabis-med.org/studies/...how.php?s_id=5

    Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
    http://www.cannabis-med.org/studies/...ow.php?s_id=23

    THC as an antiemetic in patients treated with cancer chemotherapy
    http://www.cannabis-med.org/studies/...ow.php?s_id=27

    Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC.
    http://www.cannabis-med.org/studies/...w.php?s_id=107

    Superiority of nabilone over prochlorperazine as an antiemetic
    http://www.cannabis-med.org/studies/...w.php?s_id=126

    Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy.
    http://www.cannabis-med.org/studies/...how.php?s_id=4

    Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids
    http://www.unboundmedicine.com/medli...he_least_shrew

    Mayo Study: Marijuana's THC Reduces Stomach Cramping
    http://bbsnews.net/article.php/20061029211046523

    THC effective in intractable nausea in a patient undergoing gastric bypass surgery
    http://bbsnews.net/article.php/2008020313112065

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
    http://www.medmjscience.org/Pages/science/pierson.html

    Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
    http://www.medmjscience.org/Pages/science/chang.html

    Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
    http://haworthpress.com/store/Articl...t.asp?ID=18139

    Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac.
    http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

    Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

    NEURONS/ BRAIN CELLS


    Marijuana Promotes Neuron Growth
    http://english.ohmynews.com/articlev...53377&rel_no=1

    Marijuana-Like Chemicals in the Brain Calm Neurons
    http://www.medpot.net/forums/index.php?showtopic=9686

    Marijuana May Spur New Brain Cells
    http://www.treatingyourself.com/vbul...ead.php?t=5921

    Cannabinoids promote embryonic and adult hippocampus neurogenesis
    http://www.jci.org/cgi/content/full/115/11/3104

    NEUROPATHIC PAIN


    Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain
    http://www.redorbit.com/news/health/...ource=r_health

    Cannabis-based medicine in central pain in multiple sclerosis
    http://www.neurology.org/cgi/content.../65/6/812?etoc

    Cannabis in painful HIV-associated sensory neuropathy
    http://www.cannabis-med.org/studies/...w.php?s_id=199

    Smoked cannabis therapy for HIV-related painful peripheral neuropathy
    http://www.cannabis-med.org/studies/...w.php?s_id=172

    Two cannabis based medicinal extracts for relief of central neuropathic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=143

    Cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=82

    Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain
    http://www.cannabis-med.org/studies/...ow.php?s_id=85

    Smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods.
    http://www.cannabis-med.org/studies/...ow.php?s_id=96

    Analgesic effect of the cannabinoid analogue nabilone
    http://www.cannabis-med.org/studies/...w.php?s_id=203

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Cannabis based treatments for neuropathic and multiple sclerosis-related pain.
    http://www.unboundmedicine.com/medli...s_related_pain

    Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
    http://www.ukcia.org/research/WholeP...icSymptoms.pdf

    Efficacy of 2 Cannabis based medicinal extracts for relief of central neuropathic pain
    http://www.ukcia.org/research/Centra...inEfficacy.pdf

    A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain.
    http://marijuana.researchtoday.net/archive/5/6/1703.htm

    Medicinal Marijuana Effective For Neuropathic Pain In HIV,
    http://www.sciencedaily.com/releases...0806113135.htm

    The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    NEUROPROTECTANT

    Marijuana Protects Your Brain
    http://www.roninpub.com/art-mjbrain.html

    The neuroprotective effect of cannabinoids in a rat model of Parkinson's disease
    (may need free registration)
    http://www.medscape.com/medline/abstract/17196181

    Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-THC
    http://www.unboundmedicine.com/medli...el_of_Glaucoma

    Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
    http://www.unboundmedicine.com/medli..._peroxynitrite

    Neuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells
    http://www.unboundmedicine.com/medli...l_in_AF5_cells

    Cannabidiol has a cerebroprotective action
    http://www.unboundmedicine.com/medli...ting_mechanism

    Cannabidiol but not Delta(9)-THC has a neuroprotective effect without the development of tolerance..
    http://www.unboundmedicine.com/medli...t_of_tolerance

    Delta(9)-THC) prevents cerebral infarction
    http://www.unboundmedicine.com/medli...nt_hypothermia

    Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
    http://www.unboundmedicine.com/medli...excitotoxicity

    Cannabis and Neuroprotection
    http://www.pacifier.com/~alive/cmu/c...protection.htm

    Neuroprotection by Delta 9-THC against Ouabain-Induced In Vivo Excitotoxicity
    http://www.jneurosci.org/cgi/content...urcetype=HWCIT

    Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures
    http://www.jneurosci.org/cgi/content...urcetype=HWCIT

    Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism
    http://www.nature.com/bjp/journal/v1.../0707478a.html

    The use of cannabinoids in MS: is it evidence based?
    http://www.ukcia.org/research/UseOfC...denceBased.pdf

    Neurons on Cannabinoids: Dead or Alive?
    http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf

    Cannabinoids and Brain Injury: Therapeutic Inplications
    http://www.ukcia.org/research/Cannab...rainInjury.pdf

    Cannabidiol and delta 9THC are neuroprotective antioxidants
    http://www.ukcia.org/research/Neurop...tioxidants.pdf

    Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    NUTRITION

    Oily fish makes 'babies brainier' (hemp seed oil)
    http://news.bbc.co.uk/2/hi/health/4631006.stm

    Efficacy of dietary hempseed oil in patients with atopic dermatitis. (may need free registration)
    http://www.medscape.com/medline/abst...yText=hempseed

    Effects of smoked marijuana on food intake and body weight
    http://www.cannabis-med.org/studies/...w.php?s_id=117

    Characterization, amino acid composition and in vitro digestibility of hemp (Cannabis) proteins
    http://www.sciencedirect.com/science...a3209943890e39

    HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (1)
    http://www.ratical.org/renewables/hempseed1.html

    HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (2)
    http://www.ratical.org/renewables/hempseed2.html

    Hemp seed oil: A source of valuable essential fatty acids
    http://www.hempfood.com/IHA/iha03101.html

    Occurrence of "omega-3" stearidonic acid in hemp seed
    http://www.hempfood.com/IHA/iha03208.html

    Hemp Seed Oil : The Wonder Oil For the New Millennium
    http://www.ukcia.org/research/Happi/...Millennium.htm

    Cannabis butter to spread across Europe
    http://www.globalhemp.com/News/2004/...bis_butter.php

    Hempseed as a nutritional resource: An overview
    http://www.finola.com/HempseedNutrition.pdf

    Hempseed: Nature's Perfect Food?
    http://www.marijuanalibrary.org/HT_Hempseed_0492.html

    Beta-caryophyllene is a dietary cannabinoid
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    OBSESSIVE COMPULSIVE DISORDER/ OCD

    Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol
    http://ajp.psychiatryonline.org/cgi/...full/165/4/536

    OBESITY

    Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
    http://www.medscape.com/viewarticle/525040_print

    Effects of smoked marijuana on food intake and body weight
    http://www.cannabis-med.org/studies/...w.php?s_id=117

    ORGAN TRANSPLANTS

    Marijuana Use in Potential Liver Transplant Candidates.
    http://www.unboundmedicine.com/medli...nt_Candidates_

    The debate about marijuana usage in transplant candidates: recent medical evidence on marijuana health effects
    http://www.unboundmedicine.com/medli...ealth_effects_

    OSTEOPOROSIS/ BONES


    Prototype drug to prevent osteoporosis based on cannabinoids
    http://www.news-medical.net/?id=15220

    Hebrew U. Researchers Find Cannabis Can Strengthen Bones
    http://www.israelnationalnews.com/News/News.aspx/96146

    Peripheral cannabinoid receptor, CB2, regulates bone mass
    http://www.pnas.org/cgi/content/abstract/103/3/696

    New Weapon In Battle Against Osteoporosis
    http://www.medicalnewstoday.com/articles/35621.php

    Activation of CB2 receptor attenuates bone loss in osteoporosis
    http://www.cannabis-med.org/english/...l.php?id=210#2

    Cannabis-like compound prevents bone loss
    http://www.thehempire.com/index.php/...ents_bone_loss

    The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling
    http://lib.bioinfo.pl/auth:Yirmiya,R

    Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
    http://www.unboundmedicine.com/medli...titis_in_rats_

    PAIN

    Cannabis effective at relieving pain after major surgery
    http://www.news-medical.net/?id=17995

    Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect
    http://www.medjournal.com/forum/show...87&postcount=1

    Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain,
    http://www.redorbit.com/news/health/...ource=r_health

    Cannabinoid analgesia as a potential new therapeutic option (may need free registration)
    http://www.medscape.com/medline/abstract/16449552

    Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain
    http://www.cannabis-med.org/studies/...w.php?s_id=184

    Delta-9-THC based monotherapy in fibromyalgia patients
    http://www.cannabis-med.org/studies/...w.php?s_id=194

    Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain -
    http://www.cannabis-med.org/studies/...w.php?s_id=197

    Nabilone significantly reduces spasticity-related pain
    http://www.cannabis-med.org/studies/...w.php?s_id=200

    Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.
    http://www.cannabis-med.org/studies/...w.php?s_id=178

    Are oral cannabinoids safe and effective in refractory neuropathic pain?
    http://www.cannabis-med.org/studies/...w.php?s_id=143

    Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
    http://www.cannabis-med.org/studies/...ow.php?s_id=61

    Cannabis use for chronic non-cancer pain
    http://www.cannabis-med.org/studies/...ow.php?s_id=91

    Tetrahydrocannabinol for treatment of chronic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=147

    Analgesic effect of the cannabinoid analogue nabilone
    http://www.cannabis-med.org/studies/...w.php?s_id=203

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Pain relief with oral cannabinoids in familial Mediterranean fever.
    http://www.cannabis-med.org/studies/...ow.php?s_id=18

    The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    Marihuana as a therapeutic agent for muscle spasm or spasticity.
    http://www.cannabis-med.org/studies/...ow.php?s_id=53

    Analgesic effect of delta-9-tetrahydrocannabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=16

    The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
    http://www.cannabis-med.org/studies/...ow.php?s_id=17

    Most pain patients gain benefit from cannabis in a British study
    http://www.cannabis-med.org/english/...el.php?id=84#1

    Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
    http://marijuana.researchtoday.net/archive/4/8/1384.htm

    Cannabis: Use in HIV for Pain and Other Medical Symptoms
    http://www.sciencedirect.com/science...ca04d8bd433c52

    Ajulemic acid: A novel cannabinoid produces analgesia without a “high”
    http://www.sciencedirect.com/science...cea7fb6b9bd2a5

    Therapeutic Aspects of Cannabis and Cannabinoids
    http://www.ukcia.org/research/Thereputic/Therapeut.htm

    Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
    http://www.ukcia.org/research/WholeP...icSymptoms.pdf

    ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
    http://www.ukcia.org/research/Analge...stituents.html

    NOVEL SYNERGISTIC OPIOID-CANNABINOID CODRUG FOR PAIN MANAGEMENT
    http://www.wipo.int/pctdb/en/wo.jsp?WO=2008045556

    Nabilone for the treatment of pain in fibromyalgia.
    http://www.ncbi.nlm.nih.gov/pubmed/17974490

    Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.
    http://www.cannabis-med.org/studies/...w.php?s_id=148

    Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    PANCREATITIS

    Cannabinoids ameliorate pain and reduce disease pathology in cerulein -induced acute pancreatitis
    http://ccicnewsletter.com/index.php?...#_Toc177908961

    Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells
    http://www.pubmedcentral.nih.gov/art...rtype=abstract

    PARKINSON'S DISEASE


    Marijuana Compounds May Aid Parkinson's Disease
    http://cannabisnews.com/news/19/thread19725.shtml

    Marijuana-Like Chemicals Helps Treat Parkinson's
    http://cannabisnews.com/news/22/thread22608.shtml

    Cannabis use in Parkinson's disease: subjective improvement of motor symptoms.
    http://www.cannabis-med.org/studies/...ow.php?s_id=33

    Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease
    http://www.cannabis-med.org/studies/...ow.php?s_id=54

    Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
    http://www.cannabis-med.org/studies/...w.php?s_id=153

    Evaluation of cannabidiol in dystonic movement disorders.
    http://www.cannabis-med.org/studies/...ow.php?s_id=14

    Beneficial and adverse effects of cannabidiol in a Parkinson patient
    http://www.cannabis-med.org/studies/...w.php?s_id=142

    Neuroprotective effect of cannabinoids in a rat model of Parkinson's disease
    (may need free registration)
    http://www.medscape.com/medline/abstract/17196181

    Cannabinoids in parkinsonism (3 abstracts)
    http://www.mdvu.org/emove/article.asp?ID=586

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    PATENTS RELATED TO CANNABIS

    US Patent 7344736 - Extraction of pharmaceutically active components from plant materials
    http://www.patentstorm.us/patents/7344736/fulltext.html

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery
    http://www.patentstorm.us/patents/6328992.html

    US Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment
    http://www.patentstorm.us/patents/6949582/fulltext.html

    US Patent 7402686 - Cannabinoid crystalline derivatives and process of cannabinoid purification
    http://www.patentstorm.us/patents/7402686/fulltext.html

    US Patent 6713048 - Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use
    http://www.patentstorm.us/patents/6713048/fulltext.html

    US Patent 6974568 - Treatment for cough
    http://www.patentstorm.us/patents/6974568/fulltext.html

    US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
    http://www.patentstorm.us/patents/7088914/fulltext.html

    US Patent 7399872 - Conversion of CBD to Δ-THC and Δ-THC
    http://www.patentstorm.us/patents/7399872/fulltext.html

    US Patent 6383513 - Compositions comprising cannabinoids (nasal spray)
    http://www.patentstorm.us/patents/6383513/fulltext.html

    US Patent 6132762 - Transcutaneous application of marijuana
    http://www.patentstorm.us/patents/6132762.html

    US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma
    http://www.patentstorm.us/patents/4189491.html

    POST TRAUMATIC STRESS DISORDER

    IDF TO TREAT SHELL SHOCK WITH CANNABIS
    http://www.safeaccessnow.org/article.php?id=1324

    Study: Marijuana Eases Traumatic Memories
    http://cannabisnews.com/news/13/thread13601.shtml

    Medical Marijuana: PTSD Medical Malpractice
    http://salem-news.com/articles/june1...eque_61407.php

    Cannabis for the Wounded - Another Walter Reed Scandal
    http://www.libertypost.org/cgi-bin/r...179973&Disp=11

    PTSD and Cannabis: A Clinician Ponders Mechanism of Action
    http://ccrmg.org/journal/06spr/perspective2.html

    Cannabis Eases Post Traumatic Stress
    http://ccrmg.org/journal/06spr/ptsd.html

    Endocannabinoids extinguish bad memories in the brain
    http://www.cannabis-med.org/english/...l.php?id=123#1

    Natural high helps banish bad memories
    http://www.newscientist.com/article/...-memories.html

    PREGNANCY

    Oily fish makes 'babies brainier'
    http://news.bbc.co.uk/2/hi/health/4631006.stm

    Ganja use among Jamaican women.
    http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

    Dreher's Jamaican Pregnancy Study
    http://www.november.org/stayinfo/bre...eherStudy.html

    Cannabis Relieves Morning Sickness
    http://ccrmg.org/journal/06spr/dreher.html#morning

    Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica
    http://www.druglibrary.org/Schaffer/...can-babies.htm

    The Endocannabinoid-CB Receptor System
    http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf

    CLAIM #7: MARIJUANA USE DURING PREGNANCY HARMS THE FETUS
    http://www.erowid.org/plants/cannabi...is_myth7.shtml

    More Pregnancy Highs Than Lows
    http://www.thehempire.com/index.php/...ighs_than_lows

    Medicinal cannabis use among childbearing women
    http://www.sciencedirect.com/science...6e05c3d76bf72d

    Use of anti-emetic herbs in pregnancy: women's choices, and the question of safety and efficacy
    http://www.sciencedirect.com/science...bb724ac8061090

    Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

    PRENATAL EXPOSURE

    Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica
    http://www.druglibrary.org/Schaffer/...can-babies.htm

    The Endocannabinoid-CB Receptor System
    http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf

    Ganja use among Jamaican women.
    http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

    Dreher's Jamaican Pregnancy Study
    http://www.november.org/stayinfo/bre...eherStudy.html

    Nonmutagenic action of cannabinoids in vitro
    http://content.karger.com/ProdukteDB...asp?Doi=136789

    Prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth.
    http://www.ncbi.nlm.nih.gov/sites/en...t_uids=3657756

    Tobacco and marijuana use on offspring growth from birth through 3 years of age.
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Prenatal marijuana use and neonatal outcome.
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats
    http://www.sciencedirect.com/science...f093e0645f5df2

    Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
    http://haworthpress.com/store/Articl...t.asp?ID=18139

    Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

    Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    PRIONS

    Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity
    http://www.jneurosci.org/cgi/content...act/27/36/9537

    Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
    http://bbsnews.net/article.php/20070916110536662




    PRURITIS

    Cream with endocannabinoids effective in the treatment of pruritus
    http://bbsnews.net/article.php/20051211212223236/print

    Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus.
    http://www.cannabis-med.org/studies/...w.php?s_id=196

    Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
    http://www.cannabis-med.org/studies/...w.php?s_id=116

    QUITTING OTHER DRUGS

    Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica (cocaine)
    http://www.cannabis-med.org/studies/...w.php?s_id=260

    Role of cannabinoid receptors in alcohol abuse
    http://www.medicalnewstoday.com/articles/30338.php

    Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
    http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

    Cannabis substitution "(alcohol)
    http://www.cannabis-med.org/studies/...ow.php?s_id=86

    Cannabis as a Substitute for Alcohol
    http://ccrmg.org/journal/03sum/substitutealcohol.html

    SAFETY

    Proven: Cannabis is safe medicine
    http://www.ukcia.org/research/safe-medicine.htm

    Excerpt from the Merck Manual
    http://www.ukcia.org/research/merck.htm

    Medical use of cannabinoids does not cause an increase in serious adverse health effects
    http://www.cmaj.ca/cgi/content/full/178/13/1685

    Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated
    http://www.sciencedaily.com/releases...0617125751.htm

    Alcohol and cannabis use as risk factors for injury - a case-crossover analysis in a Swiss hospital emergency department
    http://www.biomedcentral.com/1471-2458/9/40

    SAFETY-ADULTERANTS

    Smoke Pot, Get Lead Poisoning? (Germany/Europe)
    http://www.webmd.com/news/20080409/s...lead-poisoning

    Neuropsychological effects of formaldehyde use
    http://www.unboundmedicine.com/medli...maldehyde_use_

    Microbiological contaminants of marijuana
    http://www.hempfood.com/IHA/iha01205.html

    Paraquat and marijuana: epidemiologic risk assessment.
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    SATIVEX

    Questions and Answers About SATIVEX® Liquid Medical Marijuana
    http://www.mpp.org/library/questions...al-mariju.html

    Sativex in the treatment of pain caused by rheumatoid arthritis
    http://rheumatology.oxfordjournals.o. ..stract/45/1/50

    Sativex produced significant improvements in a subjective measure of spasticity
    http://www.cannabis-med.org/studies/...w.php?s_id=170

    Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
    http://www.cannabis-med.org/studies/...w.php?s_id=168

    Sativex showed positive effects in 65 per cent of patients with chronic diseases
    http://www.cannabis-med.org/english/...l.php?id=230#4

    Cannabis; adverse effects from an oromucosal spray.
    http://lib.bioinfo.pl/pmid:17703180

    Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
    http://marijuana.researchtoday.net/archive/4/8/1384.htm

    Sativex successfully treats neuropathic pain characterised by allodynia
    http://www.sciencedirect.com/science...143cfe474843b1

    Conditional okay for cannabis prescription drug
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    SCHIZOPHRENIA/ MENTAL DISORDERS

    Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia.
    (may need free registration)
    http://www.medscape.com/medline/abstract/16710682

    Symptoms of schizotypy precede cannabis use.
    http://www.ukcia.org/forum/read.php?7,7543,7579

    Cannabidiol as an antipsychotic
    http://www.cannabis-med.org/studies/...w.php?s_id=171

    Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients
    http://www.unboundmedicine.com/medli...f_cannabis_use

    Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
    http://www.unboundmedicine.com/medli..._and_Cognition

    Cannabis is a First-Line Treatment for Childhood Mental Disorders
    http://www.counterpunch.org/mikuriya07082006.html

    Cannabis does not induce schizophrenia,
    http://www.medicalnewstoday.com/articles/12283.php

    Cannabis use does not cause schizophrenia
    http://www.health.am/psy/more/cannab...schizophrenia/

    Cannabinoids and psychosis.
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Cannabis as a psychotropic medication
    http://bjp.rcpsych.org/cgi/content/full/185/1/78

    Study Shows Long Term Marijuana Users Healthy
    http://www.erowid.org/plants/cannabi...science3.shtml

    Cannabis and schizophrenia link blurs further
    http://www.newscientist.com/channel/...s-further.html

    Evidence does not show a strong causal relation between the use of cannabis and psychosocial harm
    http://www.library.nhs.uk/mentalHeal...4106&tabID=289

    No Increased Schizophrenia Risk With Use Of Cannabis
    http://www.thehempire.com/index.php/...se_of_cannabis

    Recipe For Trouble (anecdotal)
    http://www.cbsnews.com/stories/2002/...in503022.shtml

    Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
    http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

    Cannabis and psychosis
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    The Mental Health Risks of Adolescent Cannabis Use
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    SICKLE CELL DISEASE

    Sickle Cell Disease and Cannabis
    http://www.pacifier.com/~alive/cmu/Sickle_cell.htm

    Marijuana smoking in young adults with sickle cell
    http://www.illinoisnorml.org/content/view/309/

    Medical use of cannabis in sickle cell disease
    http://www.chanvre-info.ch/info/it/M...in-sickle.html

    Cannabis use in sickle cell disease: a questionnaire study.
    http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract

    SLEEP MODULATION

    Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
    http://www.medscape.com/medline/abst...44117?prt=true

    Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
    http://www.cannabis-med.org/studies/...w.php?s_id=181

    Cannabis-based medicine in central pain in multiple sclerosis.
    http://www.cannabis-med.org/studies/...w.php?s_id=175

    Two cannabis based medicinal extracts for relief of central neuropathic pain
    http://www.cannabis-med.org/studies/...ow.php?s_id=15

    Functional role for cannabinoids in respiratory stability during sleep
    http://www.pacifier.com/~alive/cmu/c...leep_apnea.htm

    THC reduces sleep apnoea in animal research
    http://www.cannabis-med.org/english/...l.php?id=120#1

    Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
    http://marijuana.researchtoday.net/archive/4/8/1384.htm

    Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
    http://marijuana.researchtoday.net/archive/4/8/1234.htm

    Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.
    http://www.ncbi.nlm.nih.gov/pubmed/1...t=AbstractPlus

    The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
    http://www.unboundmedicine.com/medli...nducing_agent_

    SMOKED CANNABIS AS A MEDICATION

    Fitness to drive in spite (because) of THC
    http://www.unboundmedicine.com/medli...use__of_THC%5D

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Effects of smoked marijuana on food intake and body weight
    http://www.cannabis-med.org/studies/...w.php?s_id=117

    Effects of smoked marijuana in experimentally induced asthma.
    http://www.cannabis-med.org/studies/...ow.php?s_id=57

    Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
    http://www.ukcia.org/research/Smoked...nAsthmatic.php

    The effects of smoked cannabis in painful peripheral neuropathy
    http://www.cannabis-med.org/studies/...ow.php?s_id=96

    Inhalation marijuana as an antiemetic for cancer chemotherapy.
    http://www.cannabis-med.org/studies/...w.php?s_id=155

    Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
    http://www.medmjscience.org/Pages/science/pierson.html

    Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
    http://www.cannabis-med.org/studies/...w.php?s_id=190

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Epilepsy patients are smoking pot
    http://www.safeaccessnow.org/article.php?id=1638

    Anticonvulsant nature of marihuana smoking
    http://www.cannabis-med.org/studies/...ow.php?s_id=39

    Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
    http://archopht.ama-assn.org/cgi/con...ct/116/11/1433

    Marihuana smoking and intraocular pressure.
    http://www.cannabis-med.org/studies/...ow.php?s_id=47

    CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
    http://www.druglibrary.org/schaffer/hemp/migrn2.htm

    Marinol vs Natural Cannabis
    http://www.norml.org/pdf_files/NORML...l_Cannabis.pdf

    Smoked cannabis therapy for HIV-related painful peripheral neuropathy
    http://www.cannabis-med.org/studies/...w.php?s_id=172

    Smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods.
    http://www.cannabis-med.org/studies/...ow.php?s_id=96

    Marijuana smoking in young adults with sickle cell
    http://www.illinoisnorml.org/content/view/309/

    Medical use of cannabis in sickle cell disease
    http://www.chanvre-info.ch/info/it/M...in-sickle.html

    Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac.
    http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

    Evaluation of herbal cannabis characteristics by medical users: a randomized trial
    http://www.pubmedcentral.nih.gov/art...medid=17101054

    Chronic Cannabis Use in the Compassionate Investigational New Drug Program
    http://www.letfreedomgrow.com/cmu/ch...nnabis_use.htm

    SOCIAL ADJUSTMENT


    Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
    http://marijuana.researchtoday.net/a.../4/11/1483.htm

    Marijuana use motives and social anxiety among marijuana-using young adults.
    http://marijuana.researchtoday.net/archive/4/8/1303.htm

    SPASTICITY

    The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
    http://www.cannabis-med.org/studies/...w.php?s_id=166

    Cannabis-based medicine in spasticity caused by multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=192

    Cannabinoids in multiple sclerosis
    http://www.cannabis-med.org/studies/...w.php?s_id=160

    Sativex produced significant improvements in a subjective measure of spasticity
    http://www.cannabis-med.org/studies/...w.php?s_id=170

    Do cannabis-based medicinal extracts have general or specific effects on symptoms in ms?
    http://www.cannabis-med.org/studies/...ow.php?s_id=56

    Efficacy, safety and tolerability of an oral cannabis extract in the treatment of spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=63

    Are oral cannabinoids safe and effective in refractory neuropathic pain?
    http://www.cannabis-med.org/studies/...w.php?s_id=143

    Experiences with THC-treatment in children and adolescents
    http://www.cannabis-med.org/studies/...ow.php?s_id=80

    The treatment of spasticity with D9-THC in patients with spinal cord injury
    http://www.cannabis-med.org/studies/...ow.php?s_id=79

    The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    Nabilone in the treatment of multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=11

    Treatment of spasticity in spinal cord injury with dronabinol
    http://www.cannabis-med.org/studies/...w.php?s_id=112

    Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
    http://www.cannabis-med.org/studies/...ow.php?s_id=10

    Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.
    http://www.cannabis-med.org/studies/...how.php?s_id=2

    Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.
    http://www.cannabis-med.org/studies/...how.php?s_id=1

    Effect of Delta-9-THC on EMG Measurements in Human Spasticity
    http://www.cannabis-med.org/studies/...w.php?s_id=110

    The effect of delta-9-THC on human spasticity.
    http://www.cannabis-med.org/studies/...w.php?s_id=154

    Cannabis effect on spasticity in spinal cord injury.
    http://www.cannabis-med.org/studies/...w.php?s_id=113

    Treatment of human spasticity with delta 9-tetrahydrocannabinol.
    ` http://www.cannabis-med.org/studies/...how.php?s_id=8

    Marihuana as a therapeutic agent for muscle spasm or spasticity.
    http://www.cannabis-med.org/studies/...ow.php?s_id=53

    The perceived effects of marijuana on spinal cord injured males.
    http://www.cannabis-med.org/studies/...w.php?s_id=138

    Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.
    http://www.unboundmedicine.com/medli...er_mutant_mice

    Cannabis-based medicine in spasticity caused by multiple sclerosis
    http://www.unboundmedicine.com/medli...iple_sclerosis

    Nabilone significantly reduces spasticity-related pain
    http://www.unboundmedicine.com/medli...ss_over_trial_

    SPINAL CORD INJURY

    The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
    http://www.cannabis-med.org/studies/...w.php?s_id=166

    Are oral cannabinoids safe and effective in refractory neuropathic pain?
    http://www.cannabis-med.org/studies/...w.php?s_id=143

    The treatment of spasticity with D9-THC in patients with spinal cord injury
    http://www.cannabis-med.org/studies/...ow.php?s_id=79

    Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
    http://www.cannabis-med.org/studies/...w.php?s_id=102

    The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    Treatment of spasticity in spinal cord injury with dronabinol
    http://www.cannabis-med.org/studies/...w.php?s_id=112

    Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
    http://www.cannabis-med.org/studies/...ow.php?s_id=10

    The effect of delta-9-THC on human spasticity.
    http://www.cannabis-med.org/studies/...w.php?s_id=154

    Cannabis effect on spasticity in spinal cord injury.
    http://www.cannabis-med.org/studies/...w.php?s_id=113

    Marihuana as a therapeutic agent for muscle spasm or spasticity.
    http://www.cannabis-med.org/studies/...ow.php?s_id=53

    The perceived effects of marijuana on spinal cord injured males.
    http://www.cannabis-med.org/studies/...w.php?s_id=138

    STROKE

    Cannabidiol has a cerebroprotective action
    http://www.unboundmedicine.com/medli...ting_mechanism

    Delta(9)-THC) prevents cerebral infarction
    http://www.unboundmedicine.com/medli...nt_hypothermia

    Medical marijuana: study shows that THC slows atherosclerosis
    http://thenexthurrah.typepad.com/the...l_marijua.html

    US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
    http://www.patentstorm.us/patents/6630507.html

    TEA AS MEDICINE

    Cannabis tea revisited: A systematic evaluation
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Cuppa Gives A Better 'ooh'
    http://www.thehempire.com/index.php/...s_a_better_ooh

    With the use of cannabis tea only a small proportion of THC in the cannabis is ingested
    http://www.ohiopatient.net/v2/content/view/906/37/

    THC/ TETRAHYDROCANNABINOL

    THC is effective in the treatment of tics in Tourette syndrome
    http://www.cannabis-med.org/studies/...ow.php?s_id=98

    THC effective in Tourette-Syndrome
    http://www.pacifier.com/~alive/cmu/tourette_thc.htm

    THC effective in Tourette syndrome in a 6-week trial
    http://www.cannabis-med.org/english/...l.php?id=146#1

    Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
    http://ajp.psychiatryonline.org/cgi/...full/156/3/495

    THC inhibits primary marker of Alzheimer's disease
    http://www.cannabis-med.org/english/...l.php?id=225#3

    THC improves appetite and reverses weight loss in AIDS patients
    http://www.cannabis-med.org/studies/...w.php?s_id=189

    Cancer-related anorexia-cachexia syndrome
    http://www.unboundmedicine.com/medli...ia_Study_Group

    THC effective in appetite and weight loss in severe lung disease (COPD)
    http://www.cannabis-med.org/english/...l.php?id=191#2

    The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
    http://www.unboundmedicine.com/medli...inoid_receptor

    Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
    http://www.unboundmedicine.com/medli..._arthritic_rat

    Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...w.php?s_id=109

    Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
    http://www.cannabis-med.org/studies/...ow.php?s_id=60

    Effects of smoked marijuana in experimentally induced asthma.
    http://www.cannabis-med.org/studies/...ow.php?s_id=57

    Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
    http://www.cannabis-med.org/studies/...ow.php?s_id=67

    New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
    http://www.medicalnewstoday.com/articles/22937.php

    Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
    http://www.ukcia.org/research/Smoked...nAsthmatic.php

    Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
    http://www.cannabis-med.org/studies/...w.php?s_id=193

    9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
    http://cancerres.aacrjournals.org/cg...act/66/13/6615

    THC and prochlorperazine effective in reducing vomiting in women following breast surgery
    http://www.cannabis-med.org/english/...l.php?id=219#1

    {Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
    http://mcr.aacrjournals.org/cgi/cont...stract/4/8/549

    Delta(9)-THC) prevents cerebral infarction
    http://www.unboundmedicine.com/medli...nt_hypothermia

    Medical marijuana: study shows that THC slows atherosclerosis
    http://thenexthurrah.typepad.com/the...l_marijua.html

    Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
    http://www.cannabis-med.org/studies/...ow.php?s_id=10

    The effect of delta-9-THC on human spasticity.
    http://www.cannabis-med.org/studies/...w.php?s_id=154

    The treatment of spasticity with D9-THC) in patients with spinal cord injury
    http://www.cannabis-med.org/studies/...ow.php?s_id=79

    Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
    http://www.cannabis-med.org/studies/...w.php?s_id=102

    The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
    http://www.cannabis-med.org/studies/...w.php?s_id=166

    Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
    http://www.unboundmedicine.com/medli..._and_Cognition

    The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
    http://www.cannabis-med.org/studies/...ow.php?s_id=12

    Marihuana as a therapeutic agent for muscle spasm or spasticity.
    http://www.cannabis-med.org/studies/...ow.php?s_id=53

    Analgesic effect of delta-9-tetrahydrocannabinol.
    http://www.cannabis-med.org/studies/...ow.php?s_id=16

    The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
    http://www.cannabis-med.org/studies/...ow.php?s_id=17

    The perceived effects of smoked cannabis on patients with multiple sclerosis.
    http://www.cannabis-med.org/studies/...ow.php?s_id=13

    Cannabis use for chronic non-cancer pain
    http://www.cannabis-med.org/studies/...ow.php?s_id=91

    Tetrahydrocannabinol for treatment of chronic pain
    http://www.cannabis-med.org/studies/...w.php?s_id=147

    Delta-9-THC based monotherapy in fibromyalgia patients
    http://www.cannabis-med.org/studies/...w.php?s_id=194

    Delta(9)-THC) prevents cerebral infarction
    http://www.unboundmedicine.com/medli...nt_hypothermia

    Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
    http://www.unboundmedicine.com/medli...excitotoxicity

    THC effective in intractable nausea in a patient undergoing gastric bypass surgery
    http://bbsnews.net/article.php/2008020313112065

    Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
    http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

    Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
    http://www.medmjscience.org/Pages/science/pierson.html

    Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
    http://www.medmjscience.org/Pages/science/chang.html


    Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
    http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

    Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol
    http://www.pubmedcentral.nih.gov/art...?artid=2279017

    The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Effects of marihuana in laboratory animals and in man
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    THC ACID/ THCA

    Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.
    http://marijuana.researchtoday.net/archive/4/8/1331.htm

    TETRAHYDROCANNABOVARIN/ THCV

    The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    Plant cannabinoids: a neglected pharmacological treasure trove
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

    TOBACCO VS CANNABIS


    Cannabis Smoke and Cancer: Assessing the Risk
    http://www.norml.org/index.cfm?Group_ID=6891

    Cannabis and tobacco smoke are not equally carcinogenic
    http://www.pubmedcentral.nih.gov/art...?artid=1277837

    Smoking Marijuana Does Not Cause Lung Cancer
    http://www.mapinc.org/drugnews/v05/n1065/a03.html

    Tobacco and marijuana use on offspring growth from birth through 3 years of age.
    http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

    Progression from marijuana use to daily smoking and nicotine dependence
    http://www.erowid.org/references/refs_view.php?ID=6951

    High anxieties - What the WHO doesn't want you to know about cannabis
    http://www.newscientist.com/article/...-cannabis.html

    Radioactive tobacco
    http://www.cannabisculture.com/news/tobacco/

    Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
    http://marijuana.researchtoday.net/a.../4/11/1483.htm

    Cannabis use when it's legal
    http://www.sciencedirect.com/science...96c8de7949a364

    Aluminum in Tobacco and Cannabis and Smoking-Related Disease
    http://www.sciencedirect.com/science...14cf03f3b4bc4e

    Marijuana Improves Fertility in Tobacco Smokers
    http://news.softpedia.com/news/Marij...rs-41535.shtml

    TOLERANCE

    A Molecular Basis of Analgesic Tolerance to Cannabinoids
    http://www.jneurosci.org/cgi/content...urcetype=HWCIT

    TOURETTE'S SYNDROME

    Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
    http://ajp.psychiatryonline.org/cgi/...full/156/3/495

    THC is effective in the treatment of tics in Tourette syndrome
    http://www.cannabis-med.org/studies/...ow.php?s_id=98

    Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol
    http://www.cannabis-med.org/studies/...ow.php?s_id=99

    Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome.
    http://www.cannabis-med.org/studies/...w.php?s_id=100

    THC effective in Tourette-Syndrome
    http://www.pacifier.com/~alive/cmu/tourette_thc.htm

    THC effective in Tourette syndrome in a 6-week trial
    http://www.cannabis-med.org/english/...l.php?id=146#1

    Cannabinoids reduce symptoms of Tourette's syndrome.
    http://www.ncbi.nlm.nih.gov/pubmed/1...,f1000m,isrctn

    Effective treatment of Tourette’s syndrome with marijuana.
    http://www.cannabis-med.org/studies/...rn=INTERACTION

    ULCERATIVE COLITIS- see CROHN'S

    VISION- see GLAUCOMA

    VAPORIZERS

    Vaporization as a smokeless cannabis delivery system
    http://www.cannabis-med.org/studies/...w.php?s_id=187

    Smokeless Cannabis Delivery Device Efficient And Less Toxic
    http://www.medicalnewstoday.com/articles/71112.php

    Volcano is to Vaporizer As Porsche is to Automobile
    http://ccrmg.org/journal/04spr/volcano.html

    Recommendation to Patients: "Don’t smoke, Vaporize"
    http://ccrmg.org/journal/03sum/vaporize.html

    Decreased respiratory symptoms in cannabis users who vaporize.
    http://marijuana.researchtoday.net/archive/4/4/1195.htm

    Use of vaporizers reduces toxins from cannabis smoke
    http://www.cannabis-med.org/english/...l.php?id=146#2

    Marijuana Water Pipe and Vaporizer Study
    http://www.ukcia.org/research/pipes.htm

    Effect of intrapulmonary tetrahydrocannabinol administration in humans.
    http://marijuana.researchtoday.net/archive/5/8/1816.htm

    US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
    http://www.patentstorm.us/patents/7088914/fulltext.html

    WILSON'S DISEASE

    Cannabis sativa and dystonia secondary to Wilson's disease. (may need free registration)
    http://www.medscape.com/medline/abstract/15390041

    WITHDRAWAL SYNDROME


    Excerpt from the Merck Manual
    http://www.ukcia.org/research/merck.htm

    Pot, Tobacco Withdrawal Equally Rough
    http://www.webmd.com/mental-health/n...-equally-rough

    A Within-Subject Comparison of Withdrawal Symptoms During Abstinence From Cannabis, Tobacco, and Both Substances
    http://www.pubmedcentral.nih.gov/art...tool=pmcentrez
     
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  6. madhu

    madhu Silver Member Silver Miner

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    You need a one year fellowship to read and digest all those articles. Marijuana genie is like credit inflation, once the genie is out it cannot put back into the bottle
     
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  7. FunnyMoney

    FunnyMoney Silver Member Silver Miner

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    After seeing all those links, I don't think there's enough earth to dig the rabbit hole deeper. Somebody's likely to sue big pharma.
     
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  8. arminius

    arminius Gold Member Gold Chaser Site Supporter ++

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    Big pharm, like the deep state is coming to a abrupt cliff with their lies. More and more folks are seeing through their Bs.

    But fear is a powerful thing.
     
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  9. nickndfl

    nickndfl Midas Member Midas Member Site Supporter ++

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    If it really was a silver bullet for cancer, don't you think George Carlin would still be alive?
     
  10. FunnyMoney

    FunnyMoney Silver Member Silver Miner

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    I found this quite interesting among the links provided.

    I had this vision where I could return to my days as a kid eating quarter pound hamburgers for dinner and ice cream for desert 10 times a week. Is it possible,,, LOL.... not likely but maybe chickenburgers and tofu ice cream.

    Here's what triggered my wishful thinking...



    Medical marijuana: study shows that THC slows atherosclerosis

    THC, or delta-9-tetrahydrocannabinol, is one of the many cannabinoids in marijuana. Cannabinoids have been shown to be medically beneficial as analgesics and anti-nausea agents, among other findings.

    Most recently, Swiss and German researchers have shown that a very small dose of THC slows the progression of atherosclerosis (clogging of the arteries) in mice. It's a pretty amazing study, especially since atherosclerosis is the leading cause of heart disease, and strokes, in the world.

    Look below the fold for details.,,,

    From: http://thenexthurrah.typepad.com/the_next_hurrah/2005/04/medical_marijua.html
     
  11. mayhem

    mayhem Silver Member Silver Miner Site Supporter

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    A whole lot of proof, and you will still look at stripped sunshine in most states if cought with it.

    Also all this proof was done under super controlled conditions, not my kitchen. Not like just popping a bud in a pipe and toking it. Also quality control is a issue. My neighbors buds are probably far different that what they used in all their research.

    As long as someone can plant a seed in the ground, big pharma won't touch it and it will always be illegal to the feds. Ya gotta follow the money guys.

    I'm all for legalized weed. But for now it looks like we are trying to push the toothpaste back into the tube. As it stands right now it is a cure for the wealthy, those who can afford it. Most people who have cancer couldn't afford to use it at today's prices.

    Also I have no clue as to wither it is curing me or not. I have had 5 years worth of radiation just from CT scans in the last 3 months. So how can I monitor it without causing more cancer from the scans?
     
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  12. Silver

    Silver Gold Member Gold Chaser

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    I've smoked it off and on for 48 years - it's not the panacea for everything. It has a lot of downsides also. If you live a healthy lifestyle, you're better off without it. It does have therapeutic properties, but all this miracle shit is hype. It's good for wasting issues from drug treatments (appetite), it's good for mild insomnia, mild depression (short term). It's also good for getting your ass thrown in jail.
     

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