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1974 STUDY: ANTINEOPLASTIC ACTIVITY OF CANNABINOIDS

G-khan

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This is hidden study done in 1974 on Cannabis and Cancer!
Requested by U.S Gov. then destroyed to cover up the results!

https://www.cureyourowncancer.org/1...-antineoplastic-activity-of-cannabinoids.html
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1974 STUDY: ANTINEOPLASTIC ACTIVITY OF CANNABINOIDS
A.E. Munson, L.S. Harris, M.A. Friedman, W.L. Dewey, and R.A. Carchman
Journal of the National Cancer Institute, Vol. 55, No. 3, September 1975


Supported by Public Health Service grant DA00490 from the National Institute on Drug Abuse, Health Services & Mental Health Administration; by a grant from the Alexander and Margaret Stewart Trust Fund; and by an institutional grant from the American Cancer Society.

Department of Pharmacology and the MCV/VCU Cancer Center, Medical College of Virginia, Virginia Commonwealth University. Richmond, Va. 23298


Abstract:

Lewis lung adenocarcinoma growth was retarded by the oral administration of delta-9-tetrahydrocannabinol, delta-8-tetrahydrocannabinol, and cannabinol (CBN), but not cannabidiol (CBD). Animals treated for 10 consecutive days with delta-9-THC, beginning the day after tumor implantation, demonstrated a dose-dependent action of retarded tumor growth. Mice treated for 20 consecutive days with delta-8-THC and CBN had reduced primary tumor size. CBD showed no inhibitory effect on tumor growth at 14, 21, or 28 days. Delta-9-THC, delta-8-THC, and CBN increased the mean survival time (36% at 100 mg/kg, 25% at 200 mg/kg, and 27% at 50 mg/kg;, respectively), whereas CBD did not. Delta-9-THC administered orally daily until death in doses of 50, 100, or 200 mg/kg did not increase the life-spans of (C57BL/6 X DBA/2) F (BDF) mice hosting the L1210 murine leukemia. However, delta-9-THC administered daily for 10 days significantly inhibited Friend leukemia virus-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for actinomycin D. Experiments with bone marrow and isolated Lewis lung cells incubated in vitro with delta-8-THC and delta-9-THC showed a dose-dependent (10 -4 10 -7) inhibition (80-20%, respectively) of tritiated thymidine and 14C -uridine uptake into these cells. CBD was active only in high concentrations (10 -4)

Introduction:

Investigations into the physiologic processes affected by the psychoactive constitutuents of marihuana [delta-9-tetrahydrocannabinol (delta-9-THC) and delta-8-tetrahydrocannabinol (delta-8-THC)] purified from Cannabis sativa are extensive (1). However, only recently have attempts been made to elucidate the biochemical basis for their cytotoxic or cytostatic activity. Leuchtenberger et al. (2) demonstrated that human lung cultures exposed to marihuana smoke showed alterations in DNA synthesis, with the appearance of anaphase bridges. Zimmerman and McClean (3), studying macromolecular synthesis in Tetrahymena, indicated that very low concentrations of delta-9-THC inhibited RNA, DNA, and protein synthesis and produced cytolysis. Stenchever et al. (4) showed an increase in the number of damaged or broken chromosomes in chronic users of marihuana. Delta-9-THC administered iv inhibited bone marrow leukopoieses (5), and Kolodny et al. (6) reported that marihuana; may impair testosterone secretion and spermatogenesis.

Furthermore, Nahas et al. (7) showed that in chronic marihuana users there is a decreased lymphocyte reactivity to mitogens as measured by thymidine uptake. These and other (8) observations suggest that marihuana (delta-9-THC) interferes with vital cell biochemical processes, though no definite mechanism has yet been established. A preliminary report from this laboratory (9) indicated that the ability of delta-9-THC to interfere with normal cell functions might prove efficacious against neoplasms. This report represents an effort to test various cannabinoids in several in vivo and in vitro tumor systems to determine the kinds of tumors that are sensitive to these compounds and reveal their possible biochemical sites of action(s).

Materials and methods

The tumor systems used were the Lewis lung adenocarcinoma, leukemia L1210, and B-tropic Friend leukemia.

In vivo systems.

Lewis lung tumor: For the maintenance of the Lewis lung carcinoma, approximately 1-mm3 pieces of tumor were transplanted into C57BL/6 mice with a 15-gauge trocar. In experiments involving chemotherapy, 14- to 18-day-old tumors were excised, cleared of debris and necrotic tissue, and cut into small fragments (=1mm3). Tumor tissue was then placed in 0.25% trypsin in Dulbecco's medium with 100 U Penicillin/ml and 100 mcg streptomycin/ml. After 90 minutes' incubation at 22 Degrees C, trypsin action was stopped by the addition of complete medium containing heat-inactivated fetal calf serum (final concentration, 20%). Cells were washed two times in complete medium, enumerated in a Coulter counter (Model ZB1) or on a hemocytometer, and suspended in serum-free medium at a concentration of 5 X 10 6 cells / ml. Next 1 X 10 6 cells were injected into the right hind gluteur muscle, and drugs administered as described in "Results." Standard regimens provided for 10 consecutive daily doses beginning 24 hours after tumor inoculation. Body weights were recorded before tumor inoculation and weekly for 2 weeks. Tumor size was measured weekly for the duration of the experiment and converted to mg tumor weight, as described by Mayo (10).

Friend leukemia: B-tropic Friend leukemia virus (FLV) was maintained in BALB / c mice, and drug evaluation performed in the same animals. Pools of virus were prepared from the plasma of mice given FLV and stored at -70 Degrees C. In experiments with FLV, 0.2 ml of a 1/20 dilution of plasma (derived from FLV-infected mice) in medium was inoculated ip into BALB / c mice. Cannabinoids were administered orally daily for 10 consecutive days beginning 24 hours after virus inoculation. Twenty-four hours after the last drug administration, the mice were killed by cervical dislocation, and the spleens removed and weighed. Mice not given FLV were treated as described above, to evaluate possible drug-induced splenomegaly.

L1210 leukemia: The murine leukemia L1210 was maintained in DBA/2 mice by weekly transfers of 10 (to the fifth power) cells derived from the peritoneal cavity. In these experiments, 10 (fifth power) leukemia cells were inoculated ip into (C57BL/6 X DBA/2) F 1 (BDF 1) mice, and the mice were treated daily for 10 consecutive days beginning 24 hours after tumor cell inoculation. Mean survival time was used as an index of drug activity.

In vitro cell systems

Lewis lung tumor: We obtained isolated Lewis lung tumor cells by subjecting 1-mm (third power) sections of tumor to 0.25% trypsin at 22 degrees C and stirring for 60-90 minutes. After trypsinization, the cells were centrifuged (1,000 rpm for 10 min) and washed twice in Dulbecco's medium containing 20% heat-inactivated fetal calf serum. They were then reconstituted to 10 7 cells/ml of 200 mm glutamine, 5,000 U penicillin, and 5,000 mcg streptomycin. Tumor cells (3-6 ml) were dispensed into 25-ml Erlenmeyer flasks and preincubated with eithe the drug or the drug vehicle for 15 minutes in a Dubnoff metabolic shaker at 37 degrees C in an atmosphere of 5% CO2--95% )2. After preincubation, 10 ucl tritiated thymidine (3H-TDR) (10 uCi, 57 Ci/mmole; New England Nuclear Corp., Boston, Mas.) was added to each flask and incubated for various times, after which 1-ml aliquots were removed and placed in 10 X 75-mm test tubes containing 1 ml 10% trichloroacetic acid (TCA) at 4 degrees C. The TCA-precipated samples were then filtered on 0.45-u Millipore filters and washed twice with 5 ml of 10% TCA at 4 degrees C. The filters were transferred to liquid scintillation vials and counted in a toluene cocktail containing Liquifluor (New England Nuclear Corp.) (4 liters toluene to 160 ml Liquifluor). Samples were then counted in a liquid scintillator.

Bone marrow: Bone marrow cells were derived from the tibias and fibulas of BDF 1 mice. One ml Dulbecco's medium containing 1 U heparin/ml was forced through each bone by a 1-ml syringe with a 26-gauge needle. The cells were washed three times, nucleated cells were enumerated on a hemocytometer, and cell viability was ascertained by trypan blue exclusion. Cell number was adjusted to 10 (seventh) cells/ml with heparin-free Dulbecco's medium and incubated at 4 degrees C for 15 minutes. Bone marrow cells were then dispensed (3-5 ml) into a25-ml Erlenmeyer flasks containing the test drug or the drug vehicle. This preincubation period was followed by the addition of 10 ul 3H-TDR and the procedures done as outlined for the isolated Lewis lung cells.

L1210: L1210 cells were derived from DBA/2 mice as described above. They were obtained from DBA/2 mice and inoculated 7 days before the experiment by the peritoneal cavity being flushed with 10 ml Dulbecco's medium containing heparin (5 u/ml). The cells were washed three times in medium, and the final medium wash did not contain heparin. The cells were resuspended at 10 (seventh) cells/ml and treated as described above. Cells were routinely counted with a hemocytometer for the determination of cell viability with trypan blue; for Lewis lung tumor and L1210 cells, a Coulter apparatus (Mode ZB1) was also used. All other reagents were of the highest quality grade available. Actinomycin D, 5-fluorouracil (5-FU), and cytosine arabinoside (ara-C) were provided by the Drug Development Branch, National Cancer Institute (NCI).

Cannabinoids: The structures of the four compounds are shown in text-figure 1.



All occur naturally in marihuana and were chemically synthesized. These drugs were provided by the National Institute on Drug Abuse or the Sheehan Institute for Research, Cambridge, Massachusetts. In the preparation of the drugs, the cannabinoids were complexed to albumin or solubilized in Emulphor-alcohol. Both preparations produced similar antitumor activity. With albumin, the cannabinoids were prepared in the following manner: A stock solution of 150 mg cannabinoid per ml absolute ethanol was made. Six ml of this solution was placed in a 200-ml flask. The ethanol was evaporated off under a stream of nitrogen and 2,100 mg lyophilized bovine serum albumin (BSA) added. After the addition of 20 ml distilled water, the substances were stirred with a glass rod in a sonicator until a good suspension was achieved. Sufficient distilled water was the aldded to make the desired dilution. Concentrations were routinely checked with a gas chromatograph. When Emulphor-alcohol was used as the vehicle, the desired amount of cannabinoid was sonicated in a solution of equal volumes by absolute ethanol and Emulphor (El-620; GAF Corp., New York, N.Y.) and then diluted with 0.15 N NaCL for a final ratio of 1: 1: 4 (ethanol: Emulphor: NaCL).

Results

Effects of Cannabinoids on Murine Tumors

Delta-9-THC, delta-8-THC, and cannabinol (CBN) all inhibited primary Lewis lung tumor growth, whereas cannabidiol (CBD) enhanced tumor growth.

Oral administration of 25, 50, or 100 mg delta-9-THC/kg inhibited primary tumor growth by 48, 72, and 75% respectively, when measured 12 days post tumor inoculation (table 1).



On day 19, mice given delta-9-THC had a 34% reduction in primary tumor size. On day 30, primary tumor size was 76% that of controls and only those given 100 mg delta-9-THC/kg had a significant increase in survival time (36%). Mice treated with a delta-9-THC showed a slight weight loss over the 2-week period (average loss, 0.3 g at 50 mg/kg and 0.1 g at 100 mg/kg). This can be compared to cyclo-ohosphamide, which caused weight loss approaching 20% (table 2).


Delta-8-THC activity was similar to that of delta-9-THC when administered orally daily until death (table 2). However, as with delta-9-THC, primary tumor growth approached control values after 3 weeks. When measured 12 days post tumor inoculation, all doses (50-400 mg/kg) of delta-8-THC inhibited primary tumor growth between 40 and 60%. Significant inhibition was also seen on day 21, which was comparable to cyclophosphamide-treated mice. Although this was not the optimum regime for cyclophosphamide, it was the positive control protocol provided by the NCI (11). All mice given delta-8-THC survived significantly longer than controls, except those treated with 100 mg/kg. Mice given 50, 200, and 400 mg/kg delta-8-THC had an increased life-span of 22.6, 24.6, and 27.2%, respectively, as compared to 33% for mice treated with 20 mg cyclophosphamide/kg. Pyran copolymer, an immunopotentiator (12) when administered at 50 mg/kg, also significantly increased the survival time of the animals (39.3%).

CBN, administered by gavage daily until death, demonstrated antitumor activity against the Lewis lung carcinoma when evaluated on day 14 post tumor inoculation (table 3).



Primary tumor growth was inhibited by 77%, at doses of 100 mg/kg on day 14 but only by 11% on day 24. At 50 mg/kg on day 14 but only by 11% on day 24. At 50 mg/kg, CBN inhibited primary tumor growth by only 32% when measured on day 14, and no inhibition was observed on day 24; however, these animals did survive 27% longer.

CBD, administered at 25 or 200 mg/kg daily until death, showed no tumor-inhibitory properties as measured by primary Lewis lung tumor size or survival time (table 4).



In this experiment, CBD-treated mice showed enhanced primary tumor growth. However, the control tumor growth rate in this experiment was decreased as compared to the previous studies.

Survival time of BDF 1 mice hosting L1210 leukemia was not prolonged by delta-9-THC treatment (table 5).



Mice treated with delta-9-THC at doses of 50, 100, and 200 mg/kg administered orally daily until death, survived 8.5, 7.8, and 8.6 days, respectively, as compared to 8.6 days for mice treated with the diluent. However, delta-9-THC inhigited FLV-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for the positive control actinomycin D (0.25 mg/kg). Although there was a dose-related inhibition, only the high dose was statistically significant (table 6).


Effect of Cannabinoids on Isolated Cells In Vitro

Isolated cells incubated in vitro represent a simple, reliable, and, hopefully, predictive method for the monitoring of the effects of agents on several biochemical parameters at the same time. The incorporation of 3H-TDR into TCA-precipitable counts in isolated Lewis lung cells is shown in text-figure 2. Similar types of curves were seen for bone marrow and L1210 cells. In all instances, for 15-45 minutes there was a linear increase in 3H-TDR uptake into the TCA-precipitable fraction. Qualitatively, similar data (not shown) were seen after a pulse with 14C-uridine. Actinomycin D (1 mcg/ml) preferentially inhibited 14C-uridine incorporation after uridine uptake had decreased to less than 30% that of control (data not shown). This is indirect evidence that we were measuring RNA synthesis.

Experiments (data not shown) done with 5-FU (10 -4 M) indicated that, in isolated bone marrow cells, both thymidine uptake with time by delta-9-THC (10 -5 M) on Lewis lung cells is depicted in text-figure 2.



In this experiment, delta-9-THC caused a nonlinear uptake of 3H-TDR. At 30 minutes, uptake of 3H-TDR into the acid-precipitable fraction was about 50% that of control Longer incubations (i.e., 60 min) did not significantly change the uptake pattern for control and de;ta-9-THC treated tumor cells. The effect of several cannabinoids on the uptake of 3H-TDR into cells incubated in vitro indicated that delta-9-THC, delta-8-THC, and CBN produced a dose-dependent inhibition of radiolabel uptake in the three cell types (table 7). These results, presented as percent inhibition of radiolabel uptake as compared to control, represented an effect of cannabinoids on one aspect of macromolecular synthesis.

CBD was the least active of the cannabinoids, but showed its greatest activity in the L1210 leukemia cells. Other data (not shown) indicate that these compounds similarly effect the uptake of 14C-uridine into the acid-precipitable fraction. Ara-C markedly inhibited 3H-TDR uptake more dramatically than did the cannabinoids (table 7). Note that delta-9-THC exhibited inhibitory properties in the isolated Lewis lung tumor and L1210 cells at concentrations that did not interfere with thymidine uptake into bone marrow cells. At certain concentrations of CBD (2,5 X 10 -6 and 2.5 X 10 -7M), radiolabel uptake was consistently stimulated in bone marrow cells and in several experiments with the isolated Lewis lung cells.

Discussion

We investigated four cannabinoids for antineoplastic activity against three animal tumor models in vivo and for cytotoxic or cystostatic activity in two tumor cell lines and bone marrow cells in vitro.

The cannabinoids (delta-9-THC, delta-8-THC, and CBN) active in vivo against the Lewis lung tumor cells are also active in the in vitro systems. The differential sensitivity of delta-9-THC against Lewis lung cells versus bone marrow cells is unique in that delta-8-THC and CBN are equally active in these systems. Johnson and Wiersma (5) reported that delta-9-THC administered iv caused a reduction in bone marrow metamyelocytes and an increase in lymphocytes. It is unclear from the data whether this is a depression of myelopoiesis or if it represents a lymphocyte infiltration into the bone marrow. The use of isolated bone marrow cells, which represent a nonneoplastic rapidly proliferating tissue, enables the rapid evaluation and assessment of drug sensititity and specificity, and thereby may predict toxicity related to bone marrow suppression.

CBD showed noninhibitory activity either against the Lewis lung cells in vivo or Lewis lung and bone marrow cells in vitro at 10 -5M an 10 -6M, respectively. Indeed, the tumor growth rate in mice treated with CBD was significantly increased over controls. This may, in part, be the consequence of the observation made in vitro (i.e., 10 -7M CBD stimulated thymidine uptake), which may be reflected by an increased rate of tumor growth. One problem related to the use of cannabinoids is the development of tolerance to many of its behavioral effects (13). It also appears that tolerance functions in the chemotherapy of neoplsms in that the growth of the Lewis lung tumor is initially markedly inhibited but, by 3 weeks, approaches that of vehicle-treated mice (tables 1, 3). This, in part, may reflect drug regimens, doses used, increased drug metabolism, or conversion to metabolites with antagonistic actions to delta-9-THC. It may also represent some tumor cell modifications rendering the cell insensitive to these drugs.

Of further interest was the lack of activity of delta-9-THC against the L1210 in vivo, whereas the invitro L1210 studies indicated that delta-9-THC could effectively inhibit thymidine uptake. The apparent reason for this discrepancy may be related to the high growth fraction and the short doubling time of this tumor. The in vitro data does not indicate that the cannabinids possess that degree of activity; e.g., ara-C, which "cures" L1210 mice, is several orders of magnitude more potent on a molar basis than delta-9-THC in vitro.

Inhibition of tumor growth and increased animal survival after treatment with delta-9-THC may, in part, be due to the ability of the drug to inhibit nucleic acid synthesis. Preliminary data with Lewis lung cells grown in tissue culture indicate that 10 -5M delta-9-THC inhibits by 50% the uptake of 3H-TDR into acid-precipitable counts over a 4-hour incubation period. Simultaneous determination of acid-soluble fractions did not show any inhibitory effects on radiolabeled uptake. Therefore, delta-9-THC may be acting at site(s) distal to the uptake of precursor. We are currently evaluating the acid-soluble pool to see if phosphorylation of precursor is involved in the action of delta-9-THC.

These results lend further support to increasing evidence that, in addition to the well-known behavioral effects of delta-9-THC, this agent modifies other cell responses that may have greater biologic significance in that they have antineoplastic activity. The high doses of delta-9-THC (i.e., 200 mg/kg) are not tolerable in humans. On a body-surface basis, this would be about 17 mg/m(2) for mice. Extrapolation to a 60-kg man would require 1,020 mg for comparable dosage. The highest doses administered to man have been 250-300 mg (14). Whether only cannabinoids active in the central nervous system (CNS) exhibit this antineoplastic property is not the question, since CBN, which lacks marihuana-like psychoactivity, is quite active in our systems (15).

With structure-activity investigations, more active agents may be designed and synthesized which are devoid of or have reduced CNS activity. That these compounds readily cross the blood-brain barrier and do not possess many of the toxic manifestations of presently used cytotoxic agents, makes them an appealing group of drugs to study.




REFERENCES

1. Singer AJ: Marihuana: Chemistry, pharmacology and patterns of social use. Ann NY Acad Sci 191: 3-261, 1971

2. Leuchtenberger C, Leuchtenberger R, Schneider A: Effects of marijuana and tobacco smoke on human lung physiology. Nature 241: 137-139,1973

3. Zimmerman AM, McClean DK: Action of narcotic and hallucinogenic agents on the cell cycle. In Drugs and the Cell Cycle (Zimmerman AM, Padilla GM. Cameron IL, eds.). New York, Academic Press, 1973, pp.67-94

4. Stenchever MA, Kunysz TJ, Allen MA: Chromosome breakage in users of marihuana. Am J Obstet Gynecol 118: 105-113, 1974

5. JohnsonRT, Wiersema V: Repression of bone marrow leukopoieses by delta-9-THC . Res Commun Chem Pathol Pharmacol 7: 613-616, 1974

6. Kolodny RC, Masters WH, Kolodner RM, et al: Depression of plasma testosterone levels after chronic intensive marijuana use. N Engl J Med 290: 872-874, 1974

7. Nahas GG, Suchu-Foca N, Armand JP, et al: Inhibition of cellular immunity in marihuana smokers. Science 183: 419-420, 1974

8. Levy JA, Munson AE, Haris LS, et al: Effect of delta-8 and delta-9-tetrahydrocannabinol on the immunre response in mice. The Pharmacologist 16: 259, 1974

9. Harris LS, Munson AE, Friedman MA, et al: Retardation of tumor growth by delta-9-tetradydrocannabinol. The Pharmacologist 16: 259, 1974

10. Mayo JG: Biologic characterization of the subcutaneously implanted Lewis lung tumor. Cancer Chemother Rep 3: 325-330, 1972

11. Geran RI, Greenberg NH, MacDonald MM, et al: Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother Rep 3: 13, 1972

12 Munson AE, Regelson W, Lawrence W: The biphasic response of the reticuloendothelial system (RES) produced by pyran copolymer and its relationship to immunologic response. J Reticuloendothel Soc 7: 375-385, 1970

13. McMillan DE, Dewey WL, Turk RF, et al: Blood levels of 3H-delta-9-tetrahydrocannabinol and its metabolites in tolerant and non-tolerant pigeons. Biochem Pharmacol 22: 383-397, 1973

14. Jones RT: The 30-day trip-clinical studies of cannabis tolerance and dependence. Proceedings of the International Conference on the Pharmacology of Cannabis. Savanah, Georgia, 1974, p.29

15. Hollister LE: Structure-activity relationships in man of cannabis constituents and homologs and metabolites of delta-9-tetrahydrocannabinol. Pharmacology 11: 3-11,


1974
 

FunnyMoney

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Sorry, I didn't read the article. Could you please give us a short summary? Does this mean that regular, small intake of Cannabis lowers one's risk of cancer?
 

Goldhedge

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#3
Sorry, I didn't read the article. Could you please give us a short summary? Does this mean that regular, small intake of Cannabis lowers one's risk of cancer?
It kills cancer cells...
 

arminius

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#5
Just checked, and yes, it's on Granny Storm Crows List. Which IMHO, needs to be spread, far and wide...

Granny Storm Crow's List

ADD/ ADHD


Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD
http://www.onlinepot.org/medical/add&mmj.htm

Cannabis as a medical treatment for attention deficit disorder
http://www.chanvre-info.ch/info/en/C...treatment.html

Cannabinoids effective in animal model of hyperactivity disorder
http://www.cannabis-med.org/english/...l.php?id=162#4

Cannabis 'Scrips to Calm Kids?
http://www.foxnews.com/story/0,2933,117541,00.html

Moderate cannabis use has a positive effect on treatment for cocaine dependence in patients with comorbid ADHD and cocaine dependence
http://bbsnews.net/article.php/20061210235129584

Cannabis Improves Symptoms of ADHD
http://cache.search.yahoo-ht2.akadns...icp=1&.intl=us

Fitness to drive in spite (because) of THC
http://www.unboundmedicine.com/medli...use__of_THC%5D

Recipe For Trouble (anecdotal)
http://www.cbsnews.com/stories/2002/...in503022.shtml


ADDICTION RISK- PHYSICAL

Women's Guide to the UofC
http://wguide.uchicago.edu/9substance.html

Cannabis Basics
http://www.erowid.org/plants/cannabi...s_basics.shtml

10 Things Every Parent, Teenager & Teacher Should Know About Marijuana (4th Q)
http://www.erowid.org/plants/cannabi...s_flyer1.shtml

Marijuana Myths, Claim No. 9
http://www.erowid.org/plants/cannabi...is_myth9.shtml

Moderate cannabis use has a positive effect on treatment for cocaine dependence in patients with comorbid ADHD and cocaine dependence
http://bbsnews.net/article.php/20061210235129584

Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Relative Addictiveness of Various Substances
http://www.ukcia.org/research/addictiv.htm

AIDS – see HIV

ALCOHOLISM

Role of cannabinoid receptors in alcohol abuse
http://www.medicalnewstoday.com/articles/30338.php

Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

Cannabis substitution
http://www.cannabis-med.org/studies/...ow.php?s_id=86

Cannabis as a Substitute for Alcohol
http://ccrmg.org/journal/03sum/substitutealcohol.html

The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism
http://www.pubmedcentral.nih.gov/art...?artid=1975858

ALLERGIES TO CANNABIS

Sensitization and Allergy to Cannabis sativa Leaves in a Population of Tomato Sensitized Patients.
http://marijuana.researchtoday.net/archive/5/2/1629.htm

Allergic rhinoconjunctivitis caused by Cannabis sativa pollen
http://www.drugs-forum.com/forum/loc...=4823&catid=21

Allergic Skin Test Reactivity to Marijuana in the Southwest
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez


ALS/ Amyotrophic Lateral Sclerosis

Cannabinol delays symptom onset
http://www.ncbi.nlm.nih.gov/sites/en..._uids=16183560

Marijuana in the management of amyotrophic lateral sclerosis
http://www.medscape.com/medline/abstract/11467101 (may need free registration)

Cannabis use in patients with amyotrophic lateral sclerosis. (may need free registration)http://www.medscape.com/medline/abstract/15055508

Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease
http://www.illinoisnorml.org/index2....o_pdf=1&id=104

ALZHEIMER'S

MARIJUANA SLOWS ALZHEIMER'S DECLINE
http://www.mapinc.org/drugnews/v05/n307/a10.html

Marijuana may block Alzheimer's
http://news.bbc.co.uk/2/hi/health/4286435.stm

Prevention of Alzheimer's Disease Pathology by Cannabinoids
http://www.jneurosci.org/cgi/content/abstract/25/8/1904

Marijuana's Active Ingredient Shown to Inhibit Primary Marker of Alzheimer's Disease
http://www.pacifier.com/~alive/articles/ca060809.htm

Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Dronabinol in the treatment of refractory agitation in Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=92

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
http://www.cannabis-med.org/studies/...ow.php?s_id=59

Cannabinoids reduce the progression of Alzheimer's disease in animals
http://www.cannabis-med.org/english/...l.php?id=187#1

Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology
http://www.unboundmedicine.com/medli...ease_Pathology

THC inhibits primary marker of Alzheimer's disease
http://www.cannabis-med.org/english/...l.php?id=225#3

Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

Alzheimer's disease; taking the edge off with cannabinoids?
http://www.nature.com/bjp/journal/v1.../0707446a.html

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Inflammation and aging: can endocannabinoids help?
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

AMOTIVATIONAL SYNDROME

Amotivational Syndrome
http://leda.lycaeum.org/?ID=12454

Marijuana Myths, Claim No. 11
http://www.erowid.org/plants/cannabi...s_myth11.shtml

Debunking 'Amotivational Syndrome'
http://www.mapinc.org/drugnews/v06/n400/a06.html

Debunking the Amotivational Syndrome
http://www.drugscience.org/Petition/C3F.html

Cannabis Use Not Linked To So-Called "Amotivational Syndrome"
http://norml.org/index.cfm?Group_ID=6824


ANECDOTAL / PERSONAL STORIES

Shared Comments and Observations
http://www.rxmarihuana.com/comments_...servations.htm

Cannabis Sativa (Marijuana) for Fibromyalgia
http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm

ANECDOTAL ARTICLES
http://cannabislink.ca/medical/#medanecdotal

Testimonials
http://www.benefitsofmarijuana.com/testimonials.html

Bud Buddies
http://budbuddies.com/buddy_testimonials.htm

ANTI-BACTERIAL PROPERTIES

Antibacterial Cannabinoids from Cannabis sativa
http://pubs.acs.org/cgi-bin/sample.c...np8002673.html

Killing bacteria with cannabis
http://arstechnica.com/journals/scie...-with-cannabis

Chemicals in Marijuana May Fight MRSA
http://www.webmd.com/news/20080904/m...may-fight-mrsa

ANTI-INFLAMMATORY PROPERTIES

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

Why Cannabis Stems Inflammation
http://www.sciencedaily.com/releases...0720222549.htm

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
http://www.unboundmedicine.com/medli...titis_in_rats_

#Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression (Alzheimer's)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Inflammation and aging: can endocannabinoids help?
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

ANTI-OXIDANT PROPERTIES

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

ANOREXIA-see APPETITE STIMULANT

ANXIOLYTIC EFFECTS

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
http://www.scielo.br/scielo.php?pid=...i_arttext#Te xt

The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings
http://fampra.oxfordjournals.org/cgi...bstract/cmn049

The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety
http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC.

Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

Single-dose study of nabilone in anxious volunteers.
http://www.cannabis-med.org/studies/...blood,pressure

APPETITE STIMULANT

Dronabinol an effective appetite stimulant?
http://www.cannabis-med.org/studies/...w.php?s_id=188

THC improves appetite and reverses weight loss in AIDS patients
http://www.cannabis-med.org/studies/...w.php?s_id=189

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
http://www.cannabis-med.org/studies/...w.php?s_id=180

Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=61

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease
http://www.cannabis-med.org/studies/...ow.php?s_id=59

Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.
http://www.cannabis-med.org/studies/...ow.php?s_id=21

Delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=52

Effect of dronabinol on nutritional status in HIV infection.
http://www.cannabis-med.org/studies/...w.php?s_id=150

Dronabinol stimulates appetite and causes weight gain in HIV patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=20

Dronabinol effects on weight in patients with HIV infection.
http://www.cannabis-med.org/studies/...ow.php?s_id=45

Recent clinical experience with dronabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=90

Dronabinol enhancement of appetite in cancer patients.
http://www.cannabis-med.org/studies/...w.php?s_id=149

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

Behavioral analysis of marijuana effects on food intake in humans.
http://www.cannabis-med.org/studies/...w.php?s_id=118

Cancer-related anorexia-cachexia syndrome
http://www.unboundmedicine.com/medli...ia_Study_Group

THC effective in appetite and weight loss in severe lung disease (COPD)
http://www.cannabis-med.org/english/...l.php?id=191#2

Machinery Of The 'Marijuana Munchies'
http://www.sciencedaily.com/releases...1226102503.htm

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-in-Cachexia-Study-Group.
http://www.medscape.com/medline/abst...49753?prt=true

Factors influencing the aggressiveness elicited by marihuana in food-deprived rats
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Immunoactive cannabinoids: Therapeutic prospects for marijuana constituentshttp://www.pubmedcentral.nih.gov/art...tool=pmcentrez

ARTHRITIS

Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
http://www.pnas.org/cgi/content/full/97/17/9561

The Cannabinergic System as a Target for Anti-inflammatory Therapies
http://www.ingentaconnect.com/conten...00013/art00008

Sativex in the treatment of pain caused by rheumatoid arthritis
http://rheumatology.oxfordjournals.o. ..stract/45/1/50

Suppression of fibroblast metalloproteinases by ajulemic acid,
http://www.ncbi.nlm.nih.gov/pubmed/16927387

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
http://www.unboundmedicine.com/medli...inoid_receptor

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
http://www.unboundmedicine.com/medli..._arthritic_rat

Cannabis based medicine eases pain and suppresses disease
http://www.medicalnewstoday.com/articles/33376.php

Pot-Based Drug Promising for Arthritis
http://www.webmd.com/rheumatoid-arth...-for-arthritis

Anti-inflammatory compound from cannabis found in herbs
http://www.rsc.org/chemistryworld/Ne...e/24060801.asp

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

US Patent 6132762 - Transcutaneous application of marijuana
http://www.patentstorm.us/patents/6132762.html

Cannabis May Suppress Immune System
http://lupus.webmd.com/news/20030415...-immune-system

ASTHMA

The Cannabinergic System as a Target for Anti-inflammatory Therapies
http://www.ingentaconnect.com/conten...00013/art00008

Acute and subacute bronchial effects of oral cannabinoids.
http://www.cannabis-med.org/studies/...ow.php?s_id=44

Comparison of bronchial effects of nabilone and terbutaline
http://www.cannabis-med.org/studies/...ow.php?s_id=43

Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
http://www.cannabis-med.org/studies/...w.php?s_id=109

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
http://www.cannabis-med.org/studies/...ow.php?s_id=60

Effects of smoked marijuana in experimentally induced asthma.
http://www.cannabis-med.org/studies/...ow.php?s_id=57

Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
http://www.cannabis-med.org/studies/...ow.php?s_id=67

New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
http://www.medicalnewstoday.com/articles/22937.php

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
http://www.ukcia.org/research/Smoked...nAsthmatic.php

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

ATHEROSCLEROSIS

Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/n...dened-arteries

Does Cannabis Hold the Key to Treating Cardiometabolic Disease (may need free registration)
http://www.medscape.com/viewarticle/525040_print

Cannabis may keep arteries clear
http://www.gnn.tv/headlines/2634/Can...arteries_clear

The Cannabinergic System as a Target for Anti-inflammatory Therapies
http://www.ingentaconnect.com/conten...00013/art00008

Cannabis compound tackles blood vessel disease
http://www.medicalnewstoday.com/articles/22658.php

Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the...l_marijua.html

Cardiovascular Effects of Cannabis
http://www.idmu.co.uk/canncardio.htm

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

AUTISM

Autism and Medical Marijuana
http://autism.com/treatable/drug/marijuana_org.htm

THE SAM PROJECT: James D.
http://www.letfreedomgrow.com/articles/james_d.htm

Medical marijuana: a valuable treatment for autism?
http://www.autismwebsite.com/ari/new.../marijuana.htm

Sam’s Story: Using Medical Cannabis to Treat Autism Spectrum Disorder
http://www.letfreedomgrow.com/cmu/SamsStory.htm

BIPOLAR DISORDER

The Use of Cannabis as a Mood Stabilizer in Bipolar Disorder: Anecdotal Evidence and the Need for Clinical Research
http://www.ukcia.org/research/TheUse...rDisorder.html

Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential.
http://www.ncbi.nlm.nih.gov/pubmed/1...,f1000m,isrctn

Recipe For Trouble (anecdotal)
http://www.cbsnews.com/stories/2002/...in503022.shtml

The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study.
http://www.cannabis-med.org/studies/...w.php?s_id=247

BLOOD PRESSURE

Lowering of Blood Pressure Through Use of Hashish
http://www.thehempire.com/index.php/...use_of_hashish

Blood Pressure Lowered With Cannabis Component
http://www.thehempire.com/index.php/...abis_component

BRAIN CELLS- see NEURONS

BRAIN- PHYSICAL EFFECTS

Effects of frequent marijuana use on brain tissue volume and composition
http://www.ukcia.org/research/Effect...omposition.htm

BONES- see OSTEOPOROSIS

CANCER- BREAST

Anandamide inhibits human breast cancer cell proliferation
http://www.pnas.org/cgi/content/abstract/95/14/8375

Inhibition of Human Breast and Prostate Cancer Cell Proliferation1
http://endo.endojournals.org/cgi/con...ract/141/1/118

Antitumor Activity of Plant Cannabinoids
http://jpet.aspetjournals.org/cgi/co...act/318/3/1375

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
http://cancerres.aacrjournals.org/cg...act/66/13/6615

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
http://www.cannabis-med.org/english/...l.php?id=220#2

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
http://www.cannabis-med.org/english/...l.php?id=219#1

Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth
http://www.thehempire.com/index.php/...wth_study_says

“Medical Marijuana” Takes On New Meaning for Metastatic Breast Cancer
http://www.healthcentral.com/breast-.../takes-cancer/

Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells
http://bbsnews.net/article.php/20071124003153693

JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells
http://www.knockoutscience.com/showa...?pmid=18454173

Cannabis Compound May Stop Metastatic Breast Cancer
http://www.washingtonpost.com/wp-dyn...111900834.html


CANCER- CERVICAL

Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells
http://www.sciencedirect.com/science...a344307d083fe1

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
http://www.webmd.com/cancer/news/200...r-in-test-tube

CANCER- COLORECTAL

Anandamide, induces cell death in colorectal carcinoma cells
http://gut.bmj.com/cgi/content/abstract/54/12/1741

Cannabinoids and cancer: potential for colorectal cancer therapy. (may need free registration)
http://www.medscape.com/medline/abstract/16042581


Marijuana takes on colon cancer
http://www.newscientist.com/article/...9_head_dn14451

Cannabis compound clue to colon cancer
http://www.newscientist.com/channel/...-alcohol_rss20


CANCER- GLIOMA/ BRAIN

Anti-tumor effects of cannabidiol
http://www.hempworld.com/HempPharm/a...ilanstudy.html

Pot’s cancer healing properties
http://www.november.org/stayinfo/bre...cerKiller.html

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
http://cancerres.aacrjournals.org/cg...ort/64/16/5617

Inhibition of Glioma Growth in Vivo
http://cancerres.aacrjournals.org/cg...61/15/5784.pdf

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
http://www.cannabis-med.org/studies/...w.php?s_id=193

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
http://www.ihop-net.org/UniPub/iHOP/...?pmid=16909207

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
http://www.medicalnewstoday.com/articles/12088.php

THC tested against brain tumour in pilot clinical study
http://www.cannabis-med.org/english/...l.php?id=222#1

THC inhibits cell cycle progression in human glioblastoma multiforme cells
http://marijuana.researchtoday.net/a.../4/10/1467.htm

Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas
http://marijuana.researchtoday.net/a.../4/12/1563.htm

Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
http://marijuana.researchtoday.net/archive/5/3/1697.htm

Anti-Tumor Effects
http://www.ukcia.org/research/AntiTumorEffects.htm

Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
http://cancerres.aacrjournals.org/cg...urcetype=HWCIT

Marijuana ingredient may reduce tumours-study
http://www.alertnet.org/thenews/newsdesk/LV470563.htm

Active Ingredient in Marijuana Kills Brain Cancer Cells
http://news.yahoo.com/s/hsn/20090401...aincancercells

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
http://www.jci.org/articles/view/37948

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CANCER- LEUKEMIA

Cannabis-induced cytotoxicity in leukemic cell lines
http://bloodjournal.hematologylibrar. ..act/105/3/1214

Cannabidiol-Induced Apoptosis in Human Leukemia Cells
http://molpharm.aspetjournals.org/cg...tract/70/3/897

Marijuana's Active Ingredient Kills Leukemia Cells
http://www.treatingyourself.com/vbul...ead.php?t=7107

Targeting CB2 cannabinoid receptors to treat malignant lymphoblastic disease
http://bloodjournal.hematologylibrar. ../100/2/627.pdf

Cannabinoids induce incomplete maturation of cultured human leukemia cells (1987)
http://www.osti.gov/energycitations/...sti_id=5164483

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
http://mcr.aacrjournals.org/cgi/cont...stract/4/8/549

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
http://www.cannabis-med.org/english/...l.php?id=220#2

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

CANCER- LUNG

Antineoplastic activity of cannabinoids
http://www.ukcia.org/research/Antine...s/default.html

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration
http://www.unboundmedicine.com/medli...stasis_in_vivo

Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways
http://ccrmg.org/journal/05aut/nocancer.html

No association between lung cancer and cannabis smoking in large study
http://www.cannabis-med.org/english/...l.php?id=219#2

Marijuana Smoking Found Non-Carcinogenic
http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

CLAIM #4: MARIJUANA CAUSES LUNG DISEASE
http://www.erowid.org/plants/cannabi...is_myth4.shtml

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
http://www.webmd.com/cancer/news/200...r-in-test-tube

Marijuana May Fight Lung Tumors
http://www.webmd.com/lung-cancer/new...ht-lung-tumors

Anti-Tumor Effects
http://www.ukcia.org/research/AntiTumorEffects.htm

Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
http://cancerres.aacrjournals.org/cg...urcetype=HWCIT

CANCER- LYMPHOMA

Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents
http://www.pacifier.com/~alive/cmu/c...d_lymphoma.htm

CANCER- MELANOMA

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
http://www.cannabis-med.org/studies/...w.php?s_id=180

Intractable nausea and vomiting due to gastrointestinal mucosal metastases
http://www.cannabis-med.org/studies/...ow.php?s_id=35

CANCER- ORAL

Smoking of cannabis does not increase risk for oral cancer
http://www.cannabis-med.org/english/...l.php?id=175#1

Marijuana use and Risk of Oral Squamous Cell Carcinoma
http://web.archive.org/web/200601121...lCarcinoma.pdf

CANCER- PANCREATIC

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells
http://cancerres.aacrjournals.org/cg...act/66/13/6748

CANCER- PROSTATE

Inhibition of Human Breast and Prostate Cancer Cell Proliferation
http://endo.endojournals.org/cgi/con...ract/141/1/118

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
http://cancerres.aacrjournals.org/cg.../65/5/1635.pdf

CANCER- RISK CANNABIS VS TOBACCO


Cannabis Smoke and Cancer: Assessing the Risk
http://www.norml.org/index.cfm?Group_ID=6891

Cannabis and tobacco smoke are not equally carcinogenic
http://www.pubmedcentral.nih.gov/art...?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer
http://www.mapinc.org/drugnews/v05/n1065/a03.html

Blunt Smokers Link Dependence Potential To Nicotine
http://www.medicalnewstoday.com/articles/52838.php

Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco
http://cannabislink.ca/medical/safer.html

Why Doesn't Smoking Marijuana Cause Cancer?
http://www.healthcentral.com/drdean/408/14275.html

Marijuana Smoking Found Non-Carcinogenic
http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

CANCER- SKIN

Inhibition of skin tumor growth
http://www.jci.org/cgi/content/full/...=MpUgjDbqHybAU

Cannabis Reduces Skin Cancer
http://www.onlinepot.org/medical/skincancerreport.htm

CANCER- TESTICULAR

The antiemetic efficacy of nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=127

Chemotherapy for Testicular Cancer
http://www.rxmarihuana.com/shared_co...cularchemo.htm

CANCER- VARIOUS/ UNNAMED

Derivatives of cannabis for anti-cancer treatment
http://www.eurekalert.org/pub_releas...o-do060605.php

Cancer Killer
http://www.november.org/stayinfo/bre...cerKiller.html

Anandamide Induces Apoptosis
http://www.jbc.org/cgi/content/abstract/275/41/31938

Nabilone improves pain and symptom management
http://www.cannabis-med.org/studies/...w.php?s_id=177

The effects of smoked cannabis in painful peripheral neuropathy
http://www.cannabis-med.org/studies/...ow.php?s_id=96

Delta-9-tetrahydrocannabinol for appetite stimulation
http://www.cannabis-med.org/studies/...ow.php?s_id=52

Dronabinol and prochlorperazine in combination
http://www.cannabis-med.org/studies/...ow.php?s_id=28

Dronabinol enhancement of appetite in cancer patients.
http://www.cannabis-med.org/studies/...w.php?s_id=149

Efficacy of tetrahydrocannabinol
http://www.cannabis-med.org/studies/...ow.php?s_id=31

Nabilone versus domperidone
http://www.cannabis-med.org/studies/...w.php?s_id=129

Inhalation marijuana as an antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=155

Nabilone vs. placebo in chemotherapy-induced nausea and vomiting
http://www.cannabis-med.org/studies/...w.php?s_id=156

The antiemetic activity of tetrahydrocanabinol versus metoclopramide
http://www.cannabis-med.org/studies/...ow.php?s_id=24

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy
http://www.cannabis-med.org/studies/...how.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
http://www.cannabis-med.org/studies/...ow.php?s_id=23

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy
http://www.cannabis-med.org/studies/...ow.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC
http://www.cannabis-med.org/studies/...w.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic
http://www.cannabis-med.org/studies/...w.php?s_id=126

Analgesic effect of delta-9-tetrahydrocannabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

Comparison of orally administered cannabis extract and delta-9-THC
http://www.unboundmedicine.com/medli...ia_Study_Group

Cannabis May Help Combat Cancer-causing Herpes Viruses
http://www.sciencedaily.com/releases...0923092627.htm

Marijuana Smoking Found Non-Carcinogenic
http://www.medpagetoday.com/Hematolo...Cancer/tb/3393

HU-331, is More Potent and Less Cardiotoxic than Doxorubicin
http://jpet.aspetjournals.org/cgi/co...ract/322/2/646

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Anti-Tumor Effects
http://www.ukcia.org/research/AntiTumorEffects.htm

Cannabinoids for Cancer Treatment: Progress and Promise
http://cancerres.aacrjournals.org/cg.../full/68/2/339

Cannabinoids and cancer: pros and cons of an antitumour strategy
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CANNABIDIOL

Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

Cannabinol delays symptom onset
http://www.ncbi.nlm.nih.gov/sites/en..._uids=16183560

Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
http://www.pnas.org/cgi/content/full/97/17/9561

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
http://www.cannabis-med.org/english/...l.php?id=220#2

Anti-tumor effects of cannabidiol
http://www.hempworld.com/HempPharm/a...ilanstudy.html

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
http://www.ihop-net.org/UniPub/iHOP/...?pmid=16909207

Cannabidiol-Induced Apoptosis in Human Leukemia Cells
http://molpharm.aspetjournals.org/cg...tract/70/3/897

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
http://www.cannabis-med.org/english/...l.php?id=220#2

Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol
http://ajp.amjpathol.org/cgi/content/full/168/1/235

Evaluation of cannabidiol in dystonic movement disorders
http://www.cannabis-med.org/studies/...ow.php?s_id=14

Cannabidiol in dystonic movement disorders.
http://www.cannabis-med.org/studies/...w.php?s_id=139

Beneficial and adverse effects of cannabidiol in a Parkinson patient
http://www.cannabis-med.org/studies/...w.php?s_id=142

Treatment of Meige's syndrome with cannabidiol.
http://www.cannabis-med.org/studies/...w.php?s_id=114

CANNABIDIOL TO HEALTHY VOLUNTEERS AND EPILEPTIC PATIENTS
http://web.acsalaska.net/~warmgun/es201.html

Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=42

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
http://www.unboundmedicine.com/medli..._peroxynitrite

EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE
http://www.druglibrary.org/schaffer/...l/hunting1.htm

The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.
(may need free registration)
http://www.medscape.com/medline/abstract/16209908

Cannabidiol has a cerebroprotective action
http://www.unboundmedicine.com/medli...ting_mechanism

Cannabidiol as an antipsychotic
http://www.cannabis-med.org/studies/...w.php?s_id=171

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
http://www.medscape.com/medline/abst...44117?prt=true

Who's Afraid of Cannabidiol?
http://www.counterpunch.org/gardner07142007.html

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
http://bbsnews.net/article.php/20070916110536662

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
http://marijuana.researchtoday.net/archive/5/6/1797.htm

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
http://www.scielo.br/scielo.php?pid=...i_arttext#Te xt

Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria
http://findarticles.com/p/articles/m...s_/ai_n9299539

Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
http://www.cannabis-med.org/studies/...ttern=EPILEPSY

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
http://www.unboundmedicine.com/medli...titis_in_rats_

The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
http://www.unboundmedicine.com/medli...nducing_agent_

Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
http://cancerres.aacrjournals.org/cg...full/64/6/1943


Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol
http://www.pubmedcentral.nih.gov/art...?artid=2279017

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CARDIOVASCULAR- see HEART DISEASE

CESAMET- see NABILONE

CHEMICAL COMPOSITION

Cannabis: A source of useful pharma compounds
http://www.medpot.net/forums/index.php?showtopic=18608

Pharmacokinetics and cannabinoid action using oral cannabis extract
http://www.pharma-lexicon.com/medica...p?newsid=29638

The chemistry and biological activity of cannabis
http://www.unodc.org/unodc/en/data-a...2_page005.html

Differential effects of medical marijuana based on strain and route of administration
http://www.ukcia.org/research/DifferentialEffects/

Cannabis / Marijuana ( Δ 9 -Tetrahydrocannabinol, THC)
http://www.nhtsa.dot.gov/people/inju...s/cannabis.htm

A chemotaxonomic analysis of cannabinoid variation in Cannabis
http://www.amjbot.org/cgi/content/full/91/6/966

The inheritance of chemical phenotype in Cannabis sativa L.
http://www.genetics.org/cgi/reprint/163/1/335.pdf

Medical Cannabis Potency Testing Project
http://www.maps.org/news-letters/v09n3/09320gie.html

Compounds found in Cannabis Sativa
http://www.ukcia.org/research/cannabis-compounds.htm

Hemp Seed Oil : The Wonder Oil For the New Millennium
http://www.ukcia.org/research/Happi/...Millennium.htm

Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria
http://findarticles.com/p/articles/m...s_/ai_n9299539

Non-cannabinoid constituents from a high potency Cannabis sativa variety.
http://www.unboundmedicine.com/medli...ativa_variety_

Cannabinoid Ester Constituents from High-Potency Cannabis sativa.
http://www.unboundmedicine.com/medli...nnabis_sativa_

Phytochemical and genetic analyses of ancient cannabis from Central Asia
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Plant cannabinoids: a neglected pharmacological treasure trove
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabis confusions
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Evaluation of herbal cannabis characteristics by medical users: a randomized trial
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CHEMOTHERAPY

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...in,combination

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
http://lib.bioinfo.pl/pmid:16408219

An efficient new cannabinoid antiemetic in pediatric oncology
http://www.druglibrary.org/olsen/hemp/iha/iha02210.html

Dronabinol and prochlorperazine in combination
http://www.ncbi.nlm.nih.gov/pubmed/1652611

Marijuana as antiemetic medicine
http://www.maps.org/docs/doblin-mt.html

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy
http://www.cannabis-med.org/studies/...ow.php?s_id=31

Inhalation marijuana as an antiemetic for cancer chemotherapy.
http://www.crrh.org/oldest/vinciguerra.html

Nabilone versus prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.pubmedcentral.nih.gov/art...?artid=1777777

Antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone
http://www.cannabis-med.org/studies/...w.php?s_id=129

THC or Compazine for the cancer chemotherapy patient
http://www.cannabis-med.org/studies/...ow.php?s_id=34

Comparison of nabilone and prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=128

Nabilone vs. prochlorperazine for refractory emesis
http://www.cannabis-med.org/studies/...w.php?s_id=146

Nabilone vs. placebo
http://www.cannabis-med.org/studies/...w.php?s_id=156

Tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics.
http://www.cannabis-med.org/studies/...ow.php?s_id=30

Comparative trial of the antiemetic effects of THC and haloperidol
http://www.cannabis-med.org/studies/...ow.php?s_id=64

Comparison of delta-9-tetrahydrocannabinol and prochlorperazine
http://www.cannabis-med.org/studies/...how.php?s_id=3

Delta 9-tetrahydrocannabinol in cancer chemotherapy.
http://www.cannabis-med.org/studies/...ow.php?s_id=88

Antiemetic effect of tetrahydrocannabinol
http://www.cannabis-med.org/studies/...how.php?s_id=6

Tetrahydrocanabinol versus metoclopramide and thiethylperazine
http://www.cannabis-med.org/studies/...ow.php?s_id=24

Effects of nabilone and prochlorperazine on chemotherapy-induced emesis
http://www.cannabis-med.org/studies/...w.php?s_id=131

Delta-9-tetrahydrocannabinol as an antiemetic
http://www.cannabis-med.org/studies/...how.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
http://www.cannabis-med.org/studies/...ow.php?s_id=23

THC as an antiemetic in patients treated with cancer chemotherapy
http://www.cannabis-med.org/studies/...ow.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC
http://www.cannabis-med.org/studies/...w.php?s_id=107

Superiority of nabilone over prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=126

Antiemetic effect of delta-9-tetrahydrocannabinol
http://www.cannabis-med.org/studies/...how.php?s_id=4

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
http://www.medmjscience.org/Pages/science/chang.html

CHILDREN/ YOUNG ADULTS

Experiences with THC-treatment in children and adolescents
http://www.cannabis-med.org/studies/...ow.php?s_id=80

An efficient new cannabinoid antiemetic in pediatric oncology.
http://www.cannabis-med.org/studies/...how.php?s_id=7

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD
http://www.onlinepot.org/medical/add&mmj.htm

Oily fish makes 'babies brainier'
http://news.bbc.co.uk/2/hi/health/4631006.stm

Cannabis is a First-Line Treatment for Childhood Mental Disorders
http://www.counterpunch.org/mikuriya07082006.html

Ganja use among Jamaican women.
http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

Dreher's Jamaican Pregnancy Study
http://www.november.org/stayinfo/bre...eherStudy.html

Cannabis Relieves Morning Sickness
http://ccrmg.org/journal/06spr/dreher.html#morning

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

Moderate cannabis use not harmful to the brain of adolescents, M R I study finds
http://www.cannabis-med.org/english/...l.php?id=218#3

No brain structural change associated with adolescent cannabis use
http://www.pubmedcentral.nih.gov/art...?artid=1524733

No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
http://www.sciencedaily.com/releases...1204123422.htm

Pot May Not Shrink Teens' Brains After All
http://www.medpagetoday.com/Neurolog...rology/tb/3242

Swiss Study Finds Marijuana Use Alone May Benefit Some Teens
http://www.foxnews.com/story/0,2933,308258,00.html

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Marijuana Use by Young People: The Impact of State Medical Marijuana Laws
http://www.mpp.org/research/teen-use-report.html

Recipe For Trouble (anecdotal)
http://www.cbsnews.com/stories/2002/...in503022.shtml

The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings
http://fampra.oxfordjournals.org/cgi...bstract/cmn049

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
http://www.cannabis-med.org/studies/...ttern=EPILEPSY

The Mental Health Risks of Adolescent Cannabis Use
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CHRONIC CYSTITIS

Cannabinoid rotation in a young woman with chronic cystitis
http://www.cannabis-med.org/studies/...w.php?s_id=115

COGNATIVE EFFECTS- see IQ

COUGH

Cannabis Cough Cure
http://www.thehempire.com/index.php/...bis_cough_cure

Novel treatment for cough (Patent)
http://appft1.uspto.gov/netacgi/nph-...DN/20060013777

CPOD

THC effective in appetite and weight loss in severe lung disease (COPD)
http://www.cannabis-med.org/english/...l.php?id=191#2

Heavy Long-Term Marijuana Use Does Not Impair Lung Function
http://www.erowid.org/plants/cannabi...s_media7.shtml

Researchers to test if cannabis ingredient can help COPD patients
http://www.thehempire.com/index.php/..._copd_patients

Heavy Habitual Marijuana Smoking Does Not Cause an Accelerated Decline in FEV with Age
http://www.ukcia.org/research/Marjiu...lineInFEV1.pdf

CROHN'S/IBS/ULCERATIVE COLITIS

Cannabis-based drugs could offer new hope for inflammatory bowel disease patients
http://www.medicalnewstoday.com/articles/28584.php

Cannabis may soothe inflamed bowels
http://www.chanvre-info.ch/info/en/C...-inflamed.html

In the Human Colon: Cannabinoids Promote Epithelial Wound Healing
http://www.gastrojournal.org/article...09297/abstract

Crohn's Patients Report Symptomatic Relief From Cannabis
http://www.thehempire.com/index.php/cannabis/news/4650

Cannabis Helps Ulcers And Crohn's Disease
http://www.thehempire.com/index.php/...crohns_disease

Bowel Study Backs Cannabis Drugs
http://www.thehempire.com/index.php/...cannabis_drugs

Cannabis use by patients with inflammatory bowel disease
http://www.sciencedirect.com/science...dcc522e0951943

Endocannabinoids and the gastrointestinal tract: what are the key questions?
http://www.nature.com/bjp/journal/v1.../0707422a.html

MARIJUANA AND IRRITABLE BOWEL SYNDROME (IBS) (anecdotal)
http://www.rxmarihuana.com/christine.htm

Marijuana and Crohn’s Disease (anecdotal)
http://www.rxmarihuana.com/chrohns3.htm

Mayo Study: Marijuana's THC Reduces Stomach Cramping
http://bbsnews.net/article.php/20061029211046523

Anti-inflammatory compound from cannabis found in herbs
http://www.rsc.org/chemistryworld/Ne...e/24060801.asp

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
http://marijuana.researchtoday.net/archive/5/6/1797.htm

Cannabinoids and gastrointestinal motility: animal and human studies.
http://www.unboundmedicine.com/medli...human_studies_

Cannabinoids and intestinal motility: welcome to CB2 receptors
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

The endogenous cannabinoid system protects against colonic inflammation
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Intestinal obstruction by an unusual foreign body
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CRUETZFELDT-JACOB DISEASE- see MAD COW DISEASE

DEPRESSION

Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant
http://www.jci.org/cgi/content/full/115/11/3104

Antidepressant-like activity by blockade of anandamide hydrolysis
http://www.pubmedcentral.nih.gov/art...medid=16352709

Decreased depression in marijuana users. (may need free registration)
http://www.medscape.com/medline/abstract/15964704


Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

Nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Cannabis and Depression
http://www.pacifier.com/~alive/cmu/d...d_cannabis.htm

Association between cannabis use and depression may not be causal, study says
http://www.cannabis-med.org/english/...l.php?id=177#4

Marijuana use and depression among adults: Testing for causal associations.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Do patients use marijuana as an antidepressant?
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Cannabis' Acts as Antidepressant
http://www.thehempire.com/index.php/...antidepressant

Cannabis And Depression Research
http://www.thehempire.com/index.php/...ssion_research

Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons
http://marijuana.researchtoday.net/a.../4/10/1460.htm

Marijuana chemical may treat depression
http://www.healthcentral.com/depress...193323-66.html

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Treating depression with cannabinoids
http://www.cannabis-med.org/english/nav/home-jcant.htm

Animal research highlights a therapeutic potential of cannabinoids for the treatment of depression
http://www.cannabis-med.org/english/..._2008_02_1.pdf

DERMATITIS

Efficacy of dietary hempseed oil in patients with atopic dermatitis. (may need free registration)
http://www.medscape.com/medline/abst...yText=hempseed

Role seen for cannabis in helping to alleviate allergic skin disease
http://www.physorg.com/news106487623.html

Marijuana Might Help Cure Allergic Contact Dermatitis (a.k.a. Poison Ivy)
http://www.healthcentral.com/skin-ca...ure-aka-ivy/1/

Substances Similar To The Body's Own 'Cannabis (Marijuana) Are Necessary For Healthy Skin And May Lead To New Skin Disease Treatments
http://www.medicalnewstoday.com/articles/113812.php

DIABETES

Cannabinoid Reduces Incidence Of Diabetes
http://www.norml.org/index.cfm?Group_ID=6909

Marijuana Compound May Help Stop Diabetic Retinopathy
http://www.sciencedaily.com/releases...0227184647.htm

Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
http://safeaccess.ca/research/diabetes.htm

Anticoagulant Effects of a Cannabis Extract in an Obese Rat Model
http://www.level1diet.com/research/id/14687

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol
http://ajp.amjpathol.org/cgi/content/full/168/1/235

The Cannabinergic System as a Target for Anti-inflammatory Therapies
http://www.ingentaconnect.com/conten...00013/art00008

Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes
http://www.unboundmedicine.com/medli..._diabetic_rats

Cannabidiol reduces the development of diabetes in an animal study
http://www.cannabis-med.org/english/...l.php?id=219#3

Getting Eye On Cannabinoids
http://www.thehempire.com/index.php/...n_cannabinoids

Marijuana compound could prevent eye damage in diabetics
http://www.thehempire.com/index.php/...e_in_diabetics

The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice
http://www.uccs.edu/~rmelamed/Evolut...e_disease.html

Cannabidiol arrests onset of autoimmune diabetes in NOD mice
http://safeaccess.ca/research/diabetes.htm

#Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

DRIVING AND CANNABIS

Abstracts of several studies
http://www.ukcia.org/research/medline/8.htm

Cannabis and driving
http://www.ukcia.org/research/driving4.html

CANNABIS AND ROAD SAFETY
http://www.ukcia.org/research/driving2.htm

Marijuana And Actual Driving Performance
http://www.ukcia.org/research/driving.htm

Cannabis and Driving: A Scientific and Rational Review
http://norml.org/index.cfm?Group_ID=7459

Fitness to drive in spite (because) of THC
http://www.unboundmedicine.com/medli...use__of_THC%5D

DRONABINOL also see MARINOL

GENERIC NAME: DRONABINOL - ORAL (dro-NAB-in-all)
BRAND NAME(S): Marinol
http://www.medicinenet.com/dronabinol-oral/article.html


Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Dronabinol in the treatment of refractory agitation in Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=92

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
http://www.cannabis-med.org/studies/...ow.php?s_id=59

Dronabinol an effective appetite stimulant?
http://www.cannabis-med.org/studies/...w.php?s_id=188

Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Effect of dronabinol on nutritional status in HIV infection.
http://www.cannabis-med.org/studies/...w.php?s_id=150

Dronabinol stimulates appetite and causes weight gain in HIV patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=20

Dronabinol effects on weight in patients with HIV infection.
http://www.cannabis-med.org/studies/...ow.php?s_id=45

Recent clinical experience with dronabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=90

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
http://www.cannabis-med.org/studies/...w.php?s_id=180

Dronabinol and prochlorperazine in combination
http://www.cannabis-med.org/studies/...ow.php?s_id=28

Dronabinol enhancement of appetite in cancer patients.
http://www.cannabis-med.org/studies/...w.php?s_id=149

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

Dronabinol and retinal hemodynamics in humans.
http://www.cannabis-med.org/studies/...w.php?s_id=202

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

Nausea relieved by tetrahydrocannabinol (dronabinol).
http://www.cannabis-med.org/studies/...ow.php?s_id=35

Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
http://www.cannabis-med.org/studies/...w.php?s_id=116

Treatment of spasticity in spinal cord injury with dronabinol
http://www.cannabis-med.org/studies/...w.php?s_id=112

Cannabinoid Activator Mellows Out Colon
http://www.medpagetoday.com/MeetingCoverage/ACG/tb/4410

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
http://marijuana.researchtoday.net/archive/4/8/1234.htm

Mayo Study: Marijuana's THC Reduces Stomach Cramping
http://bbsnews.net/article.php/20061029211046523

Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol
http://ajp.psychiatryonline.org/cgi/...full/165/4/536

DRUG INTERACTIONS- see INTERACTIONS WITH OTHER DRUGS

DRUG TESTING

Hemp oil causes positive urine tests for THC
http://www.druglibrary.org/crl/drugt...JAnToxicol.pdf

Deposition of cannabinoids in hair after long-term use of cannabis
http://marijuana.researchtoday.net/archive/4/7/1002.htm

Cannabinoid concentrations in hair from documented cannabis users.
http://marijuana.researchtoday.net/archive/4/6/924.htm

Detection time of regular THC use in urine shorter than often assumed
http://www.acmed.org/english/bulleti...l.php?id=213#2

Differentiation between drug use and environmental contamination when testing for drugs in hair
http://www.sciencedirect.com/science...ad1bd10fb041bf

The effects of adulterants and selected ingested compounds on drugs-of-abuse testing in urine.
http://marijuana.researchtoday.net/archive/4/8/1389.htm

Toxicity From the Use of Niacin to Beat Urine Drug Screening
http://www.sciencedirect.com/science...9d8b53ea07c431

Evaluation of the IDS One-Step™ ELISA kits for the detection of illicit drugs in hair
http://www.sciencedirect.com/science...65bbd05717cb04

Deposition of cannabinoids in hair after long-term use of cannabis
http://www.sciencedirect.com/science...df7a40474cf025

Excretion of Δ9-tetrahydrocannabinol in sweat
http://www.sciencedirect.com/science...98c2e3fc4989d1

Portable Oral-Fluid Tests Still Unreliable For Pot, Study Says
http://norml.org/index.cfm?Group_ID=7636

Current Developments in Drug Testing in Oral Fluid.
http://www.drug-monitoring.com/pt/re...195628!8091!-1

Drug-Test Cheats Try New Tricks on Labs
http://www.webmd.com/mental-health/n...tricks-on-labs

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
http://www.cannabis-med.org/studies/...ttern=EPILEPSY

Marijuana Use More Prevalent With Epilepsy
http://www.medscape.com/viewarticle/465891

Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

DYSTONIA

Cannabis sativa and dystonia secondary to Wilson's disease. (may need free registration)
http://www.medscape.com/medline/abstract/15390041

Experiences with THC-treatment in children and adolescents
http://www.cannabis-med.org/studies/...ow.php?s_id=80

Evaluation of cannabidiol in dystonic movement disorders
http://www.cannabis-med.org/studies/...ow.php?s_id=14

Cannabidiol in dystonic movement disorders.
http://www.cannabis-med.org/studies/...w.php?s_id=139

Beneficial and adverse effects of cannabidiol in a Parkinson patient
http://www.cannabis-med.org/studies/...w.php?s_id=142

Treatment of Meige's syndrome with cannabidiol.
http://www.cannabis-med.org/studies/...w.php?s_id=114

ENDOCANNABINOID DEFICIENCY

Clinical Endocannabinoid Deficiency
http://www.freedomtoexhale.com/clinical.pdf

The endocannabinoid system is dysregulated in multiple sclerosis
http://brain.oxfordjournals.org/cgi/...tract/awm160v1

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/...ll/126/10/2191

Migraine may be related to under production of cannabinoids
http://www.illinoisnorml.org/index2....o_pdf=1&id=755

Endocannabinoids: Multi-scaled, Global Homeostatic Regulators of Cells and Society
http://knowledgetoday.org/wiki/index.php/ICCS06/70

EPILEPSY

Epilepsy patients are smoking pot
http://www.safeaccessnow.org/article.php?id=1638

Experiences with THC-treatment in children and adolescents
http://www.cannabis-med.org/studies/...ow.php?s_id=80

Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=42

Anticonvulsant nature of marihuana smoking.
http://www.cannabis-med.org/studies/...ow.php?s_id=39

Cannabis may help epileptics
http://www.medicalnewstoday.com/articles/4423.php

Hypnotic and Antiepileptic Effects of Cannabidiol
http://www.thecompassionclub.org/med...ue&pageNumber=

Marijuana: an effective antiepileptic treatment in partial epilepsy?
http://www.cannabis-med.org/studies/...w.php?s_id=157

Marijuana and Epilepsy (anecdotal)
http://www.rxmarihuana.com/epilepsy.htm

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
http://www.cannabis-med.org/studies/...ttern=EPILEPSY

Marijuana Use More Prevalent With Epilepsy
http://www.medscape.com/viewarticle/465891

Endocannabinoids and Their Implications for Epilepsy
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

FAMILIAL MEDITERRANEAN FEVER

Pain relief with oral cannabinoids in familial Mediterranean fever.
http://www.cannabis-med.org/studies/...ow.php?s_id=18

FERTILITY

Synthetic Cannabinoid May Aid Fertility In Smokers
http://www.medicalnewstoday.com/articles/58063.php

FEVER

A Novel Role of Cannabinoids
http://jpet.aspetjournals.org/cgi/co...ull/320/3/1127

A Cooling Effect From Cannabis?
http://ccrmg.org/journal/05aut/coolcannabis.html

Marijuana Might Really Make You Cool
http://www.thehempire.com/index.php/..._make_you_cool

FIBROMYALGIA

Delta-9-THC based monotherapy in fibromyalgia patients
http://www.immunesupport.com/library...293&t=CFIDS_FM

Clinical Endocannabinoid Deficiency
http://www.freedomtoexhale.com/clinical.pdf

Cannabis Sativa (Marijuana) for Fibromyalgia
http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm

THC Reduces Pain in Fibromyalgia Patients
http://www.illinoisnorml.org/content/view/63/35/

Fibromyalgia: Effective Treatment with Medical Marijuana
http://www.salem-news.com/articles/n...gia_112807.php

Cannabis Science: Nabilone reduced chronic pain caused by fibromyalgia
http://bbsnews.net/article.php/20071111150357312

Fibromyalgia and Medical Marijuana
http://www.webmd.com/fibromyalgia/gu...ical-marijuana

Nabilone for the treatment of pain in fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/17974490

GASTRIC BYPASS

THC effective in intractable nausea in a patient undergoing gastric bypass surgery
http://bbsnews.net/article.php/2008020313112065

GATEWAY THEORY

The Myth of Marijuana's Gateway Effect
http://www.druglibrary.org/schaffer/library/mjgate.htm

Endogenous cannabinoids are not involved in cocaine reinforcement
http://www.sciencedirect.com/science...4e861a90579fac

No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
http://www.sciencedaily.com/releases...1204123422.htm

CLAIM #13:MARIJUANA IS A "GATEWAY" TO THE USE OF OTHER DRUGS
http://www.erowid.org/plants/cannabi...s_myth13.shtml

Gateway To Nowhere? The Evidence That Pot Doesn't Lead To Heroin
http://www.thehempire.com/index.php/...lead_to_heroin

Cannabis use when it's legal
http://www.sciencedirect.com/science...96c8de7949a364

Cannabis Use- A Gateway to other Drugs? The Case of Amsterdam
http://www.ukcia.org/research/Cannab...ppingStone.pdf

Twin study fails to prove 'gateway' hypothesis
http://www.ukcia.org/research/Escala...veGateway.html

GLAUCOMA/ VISION

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
http://archopht.ama-assn.org/cgi/con...ct/116/11/1433

Dronabinol and retinal hemodynamics in humans.
http://www.cannabis-med.org/studies/...w.php?s_id=202

Effect of Sublingual Application of Cannabinoids on Intraocular Pressure
http://www.cannabis-med.org/studies/...w.php?s_id=201

Delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.
http://www.cannabis-med.org/studies/...ow.php?s_id=88

Effect of marihuana on intraocular and blood pressure in glaucoma.
http://www.cannabis-med.org/studies/...ow.php?s_id=87

Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans.
http://www.cannabis-med.org/studies/...ow.php?s_id=40

Marihuana smoking and intraocular pressure.
http://www.cannabis-med.org/studies/...ow.php?s_id=47

Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-Tetrahydrocannabinol
http://www.unboundmedicine.com/medli...el_of_Glaucoma

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
http://www.unboundmedicine.com/medli..._peroxynitrite

Effects of tetrahydrocannabinol on arterial and intraocular hypertension.
(may need free registration)
http://www.medscape.com/medline/abstract/468444

Cannabis improves night vision:
http://www.sciencedirect.com/science...d0a198efd77cb6

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma
http://www.patentstorm.us/patents/4189491.html

Reduction of Congenital Nystagmus in a Patient after Smoking Cannabis.
http://www.unboundmedicine.com/medli...king_Cannabis_

Cannabinoids and glaucoma
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

CONJUGATE DEVIATION OF THE EYES AFTER Cannabis indica INTOXICATION*
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

GYNOCOLOGY AND OBSTETRICS

Cannabis Treatments in Obstetrics and Gynecology: A Historical Review
http://www.freedomtoexhale.com/russo-ob.pdf

HEADACHE- see MIGRAINE

HEART DISEASE/ CARDIOVASCULAR

Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/n...dened-arteries

The endogenous cardiac cannabinoid system: a new protective mechanism
http://www.ncbi.nlm.nih.gov/pubmed/16618028

Cardiovascular pharmacology of cannabinoids.
http://www.biowizard.com/story.php?pmid=16596789

Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia
http://www.ingentaconnect.com/conten...20001/00002346

Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
http://www.medscape.com/viewarticle/525040_print

Cannabinoid Offers Cardioprotection
http://www.norml.org/index.cfm?Group...m_format=pri nt

Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks
http://www.norml.org/index.cfm?Group_ID=6972

Marijuana use, diet, body mass index, and cardiovascular risk factors (may need free registration)
http://www.medscape.com/medline/abstract/16893701

Cannabinoids and cardiovascular disease
http://www.unboundmedicine.com/medli...cal_treatments

Cannabinoids as therapeutic agents in cardiovascular disease
http://www.unboundmedicine.com/medli..._and_illusions

The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol
http://www.unboundmedicine.com/medli...oxide_synthase

Cannabinoids prevented the development of heart failure in animal study
http://www.cannabis-med.org/english/...l.php?id=145#2

Cannabis use not associated with risk factors for diseases of heart and circulation
http://www.cannabis-med.org/english/...l.php?id=225#2

THC protects heart cells in the case of lowered oxygen supply
http://www.cannabis-med.org/english/...l.php?id=212#1

Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the...l_marijua.html

Cardiovascular Effects of Cannabis
http://www.idmu.co.uk/canncardio.htm

Changes in middle cerebral artery velocity after marijuana
http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract

Cannabidiol protects against myocardial ischemic reperfusion injury.
http://marijuana.researchtoday.net/a.../4/12/1404.htm

Function of cannabinoids in heart failure]
http://www.unboundmedicine.com/medli...art_failure%5D

Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez



HEPATITIS

Moderate Cannabis Use Associated with Improved Treatment Response
http://www.hivandhepatitis.com/hep_c.../091506_a.html

Cannabis use improves retention and virological outcomes in patients treated for hepatitis C
http://www.natap.org/2006/HCV/091506_02.htm

Hepatitis C - The Silent Killer Can Medical Cannabis Help?
http://www.pacifier.com/~alive/cmu/hepatitis_c.htm

Study: Pot Helps Hepatitis Treatment
http://www.thehempire.com/index.php/...itis_treatment

Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids
http://molpharm.aspetjournals.org/cg...stract/74/1/20

Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus.
http://www.cannabis-med.org/studies/...w.php?s_id=165

HERPES

Cannabis May Help Combat Cancer-causing Herpes Viruses
http://www.sciencedaily.com/releases...0923092627.htm

THC inhibits lytic replication of gamma oncogenic herpes viruses in vitro
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Suppressive effect of delta-9-tetrahydrocannabinol on herpes simplex virus infectivity in vitro
http://www.ebmonline.org/cgi/content/abstract/196/4/401

Inhibition of cell-associated herpes simplex virus
http://www.ebmonline.org/cgi/content/abstract/185/1/41

The Effect of {Delta}-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication
http://vir.sgmjournals.org/cgi/conte...tract/49/2/427

HICCUPS

Marijuana cures hiccups
http://www.yourhealthbase.com/database/a77k.htm

Marijuana For Intractable Hiccups
http://cannabislink.ca/medical/hiccups.html

HISTORICAL STUDIES


The La Guardia Committee Report
http://www.druglibrary.org/schaffer/...ag/lagmenu.htm

Physical, Mental, and Moral Effects of Marijuana: The Indian Hemp Drugs Commission Report
http://www.druglibrary.org/schaffer/Library/effects.htm

MARIAJUANA SMOKING IN PANAMA
http://www.druglibrary.org/schaffer/...ma/panama1.htm

The British Pharmaceutical Codex – 1934
http://www.druglibrary.org/schaffer/...cal/brit34.htm

ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH
http://www.druglibrary.org/schaffer/...850/gunjah.htm

DISPENSATORY OF THE UNITED STATES OF AMERICA Fifth Edition (1843)
http://www.druglibrary.org/schaffer/...y/dispensa.htm

New Remedies:pharmaceutically and Therapeutically Considered Fourth Edition (1843)
http://www.druglibrary.org/schaffer/...y/dunglisn.htm

On the Haschisch or Cannabis Indica
http://www.druglibrary.org/schaffer/...y/bellhash.htm

ON INDICATIONS OF THE HACHISH-VICE IN THE OLD TESTAMENT
http://www.druglibrary.org/schaffer/...ory/hashot.htm

The Physiological Activity of Cannabis Sativa
http://www.druglibrary.org/schaffer/...story/japa.htm

CANNABIS, U.S.P. (American Cannabis):
http://www.druglibrary.org/schaffer/...y/vbchmed1.htm

History of Cannabis and Its Preparations in Saga, Science and Sobriquethttp://www3.interscience.wiley.com/c...06128/PDFSTART

Observations on the medicinal properties of the Cannabis Sativa of India
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabis Sativa Seu Indica: Indian Hemp
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Collapse after intravenous injection of hashish. (1968)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Adverse Effects of Intravenous Cannabis Tea (1977)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Paraquat and marijuana: epidemiologic risk assessment. (1978)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Hashish and drug abuse in Egypt during the 19th and 20th centuries.
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Marihuana and drug abuse. Recommendations of the Committee on Public Health, New York Academy of Medicine. (1973)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Observations on the Cannabis Indica, or Indian Hemp (1843)
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

A Case of Dysmenorrhœa in Which the Tincture of Cannabis Indica Was Employed, with Some Observations upon That Drug
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

HIV / AIDS

Marijuana Use Does Not Accelerate HIV Infection
http://paktribune.com/news/print.php?id=139255

THC improves appetite and reverses weight loss in AIDS patients
http://www.cannabis-med.org/studies/...w.php?s_id=189

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

Cannabis in painful HIV-associated sensory neuropathy
http://www.cannabis-med.org/studies/...w.php?s_id=199

Smoked cannabis therapy for HIV-related painful peripheral neuropathy
http://www.cannabis-med.org/studies/...w.php?s_id=172

Short-term effects of cannabinoids in patients with HIV-1 infection
http://www.cannabis-med.org/studies/...ow.php?s_id=62

Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.
http://www.cannabis-med.org/studies/...ow.php?s_id=21

Effect of dronabinol on nutritional status in HIV infection.
http://www.cannabis-med.org/studies/...w.php?s_id=150

Dronabinol stimulates appetite and causes weight gain in HIV patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=20

Dronabinol effects on weight in patients with HIV infection.
http://www.cannabis-med.org/studies/...ow.php?s_id=45

Recent clinical experience with dronabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=90

Marijuana as therapy for people living with HIV/AIDS: Social and health aspects
http://www.unboundmedicine.com/medli...health_aspects

Marijuana and AIDS: A Four-Year Study
http://ccrmg.org/journal/05spr/aids.html

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
http://marijuana.researchtoday.net/archive/4/8/1234.htm

Cannabis: Use in HIV for Pain and Other Medical Symptoms
http://www.sciencedirect.com/science...ca04d8bd433c52

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Denbinobin... inhibits HIV-1 replication through an NF-kappaB-dependent pathway.
http://marijuana.researchtoday.net/a.../5/10/2003.htm

HORMONES

Effects of chronic marijuana use on testosterone, luteinizing hormone, follicle stimulating hormone, prolactin and cortisol in men and women.
http://www.ncbi.nlm.nih.gov/pubmed/1935564

Marijuana: interaction with the estrogen receptor
http://jpet.aspetjournals.org/cgi/co...ract/224/2/404

Endocrine Effects of Marijuana
http://www.ukcia.org/research/EndocrineEffects.pdf


HUNTINGTON'S DISEASE

EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE
http://www.druglibrary.org/schaffer/...l/hunting1.htm

Nabilone Could Treat Chorea and Irritability in Huntington’s Disease
http://neuro.psychiatryonline.org/cg...18/4/553?rss=1


HYSTERECTOMY

Effect of nabilone on nausea and vomiting after total abdominal hysterectomy
http://www.cannabis-med.org/studies/...w.php?s_id=137

IBS- see CROHN'S

IDIOPATHIC INTRACRANIAL HYPERTENSION

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

INTERACTIONS WITH OTHER DRUGS

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and prochlorperazine in combination
http://www.cannabis-med.org/studies/...ow.php?s_id=28

Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect
http://www.medjournal.com/forum/show...87&postcount=1

Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=197

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.
http://www.cannabis-med.org/studies/...w.php?s_id=178

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
http://www.unboundmedicine.com/medli..._arthritic_rat

Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.
http://www.cannabis-med.org/studies/...w.php?s_id=148

Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel.
http://www.cannabis-med.org/studies/...rn=INTERACTION

IQ/ MEMORY/ COGNITIVE EFFECTS

Findings of a longitudinal study of effects on IQ
http://www.cmaj.ca/cgi/content/full/166/7/887

Heavy cannabis use without long-term effect on global intelligence
http://www.cannabis-med.org/english/...l.php?id=115#2

Marijuana does not dent IQ permanently
http://www.newscientist.com/article/...rmanently.html

Cannabis use and cognitive decline in persons under 65 years of age
http://www.ukcia.org/research/Cannab...veDecline.html

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats

http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
http://www.unboundmedicine.com/medli...annabis_users_

Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study.
http://www.ncbi.nlm.nih.gov/pubmed/12901774

Review: executive functioning and cannabis use.
http://www.unboundmedicine.com/medli...nnabis_use_%5D

Neuropsychological effects of marijuana
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

LONG TERM USE EFFECTS

Long-Term Marijuana Users Suffer Few Health Problems, Australian Study Indicates
http://www.ukcia.org/research/aus.htm

Neuropsychological Performance in Long-term Cannabis Users
http://www.ukcia.org/research/Neurop...nabisUsers.htm

Long term marijuana users seeking medical cannabis in California
http://www.harmreductionjournal.com/content/4/1/16

LUPUS

Cannabis May Suppress Immune System
http://lupus.webmd.com/news/20030415...-immune-system

Systemic Lupus by Dawn (anecdotal)
http://www.erowid.org/experiences/exp.php?ID=49481

MAD COW/ CRUETZFELDT-JACOB DISEASE

Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity
http://www.jneurosci.org/cgi/content...act/27/36/9537

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
http://bbsnews.net/article.php/20070916110536662

MARINOL/ SYNTHETICS/ CANNABINOID MIXTURES

CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
http://www.druglibrary.org/schaffer/hemp/migrn2.htm

Marinol vs Natural Cannabis
http://www.norml.org/pdf_files/NORML...l_Cannabis.pdf

The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.
(may need free registration)
http://www.medscape.com/medline/abstract/16209908

Unheated Cannabis sativa extracts and its major compound THC-acid
http://www.ncbi.nlm.nih.gov/pubmed/16504929

Side effects of pharmaceuticals not elicited by comparable herbal medicines.
http://content.herbalgram.org/youngl...ew.asp?i=41444

Sativex in the treatment of pain caused by rheumatoid arthritis
http://rheumatology.oxfordjournals.o. ..stract/45/1/50

Is dronabinol an effective appetite stimulant?
http://www.cannabis-med.org/studies/...w.php?s_id=188

Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
http://www.cannabis-med.org/studies/...w.php?s_id=168

Sativex® in patients with symptoms of spasticity due to multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=169

Nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases
http://www.cannabis-med.org/studies/...w.php?s_id=180

Synthetic cannabinomimetic nabilone on patients with chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=197

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Sativex produced significant improvements in a subjective measure of spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=170

Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain
http://www.cannabis-med.org/studies/...ow.php?s_id=85

Cannabinoid rotation in a young woman with chronic cystitis
http://www.cannabis-med.org/studies/...w.php?s_id=115

Dronabinol in patients with intractable pruritus
http://www.cannabis-med.org/studies/...w.php?s_id=116

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease:
http://www.cannabis-med.org/studies/...ow.php?s_id=54

Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
http://www.cannabis-med.org/studies/...w.php?s_id=153

Nabilone in the treatment of multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Big Pharma's Strange Holy Grail: Cannabis Without Euphoria?
http://www.counterpunch.org/gardner07082006.html

Sativex showed positive effects in 65 per cent of patients with chronic diseases
http://www.cannabis-med.org/english/...l.php?id=230#4

Medical use of cannabinoids does not cause an increase in serious adverse health effects
http://www.cmaj.ca/cgi/content/full/178/13/1685

MEIGE'S SYNDROME

Treatment of Meige's syndrome with cannabidiol.
http://www.cannabis-med.org/studies/...w.php?s_id=114

MEMORY- see IQ

MENTAL DISORDERS- see SCHIZOPHRENIA

IGRAINE/ HEADACHE

CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
http://www.druglibrary.org/schaffer/hemp/migrn2.htm

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

Cannabis and Migraine
http://www.pacifier.com/~alive/cmu/c...d_migraine.htm

Clinical Endocannabinoid Deficiency
http://www.freedomtoexhale.com/clinical.pdf

Hemp for Headache
http://www.freedomtoexhale.com/hh.pdf

Chronic Migraine Headache
http://www.druglibrary.org/schaffer/hemp/migrn1.htm

Cannabis for Migraine Treatment: Once and Future Treatment?
http://www.druglibrary.org/crl/pain/...ne_%20Pain.pdf

Cannabinoids block release of serotonin from platelets induced by plasma from migraine patients
http://www.ukcia.org/research/Cannab...Platelets.html

Migraine may be related to under production of cannabinoids
http://www.illinoisnorml.org/index2....o_pdf=1&id=755

Cluster Attacks Responsive to Recreational Cannabis and Dronabinol.
http://www.ncbi.nlm.nih.gov/pubmed/1...Pubmed_RVBrief

Inhaled Cannabis Aborts Cluster Headaches, Journal Reports
http://norml.org/index.cfm?Group_ID=7817

MORNING SICKNESS

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

Medicinal cannabis use among childbearing women
http://safeaccess.ca/research/cannabis_nausea2006.pdf

Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
http://haworthpress.com/store/Articl...t.asp?ID=18139

MORTALITY RATES

Marijuana use and mortality.
http://www.pubmedcentral.nih.gov/art...?artid=1380837

Marijuana Smoking Doesn't Lead to Higher Death Rate
http://ccrmg.org/journal/03sum/kaiser.html

How deadly is marijuana?
http://www.medicalnewstoday.com/articles/4426.php

MS/ MULTIPLE SCLEROSIS

Sativex in patients with symptoms of spasticity due to multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=169

Marijuana derivatives may provide MS treatment
http://www.health.am/ab/more/marijua..._ms_treatment/

Marijuana Helps MS Patients Alleviate Pain, Spasms
http://www.mult-sclerosis.org/news/S...msAndPain.html

Cannabis-based medicine in central pain in multiple sclerosis
http://www.neurology.org/cgi/content.../65/6/812?etoc

Cannabis-based medicine in spasticity caused by multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=192

Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
http://www.cannabis-med.org/studies/...w.php?s_id=168

The effect of cannabis on urge incontinence in patients with multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=185

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Cannabinoids in multiple sclerosis (CAMS) study
http://www.cannabis-med.org/studies/...w.php?s_id=160

Sativex produced significant improvements in a subjective measure of spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=170

Cannabis-based medicine in central pain in multiple sclerosis.
http://www.cannabis-med.org/studies/...w.php?s_id=175

Do cannabis-based medicinal extracts have general or specific effects
http://www.cannabis-med.org/studies/...ow.php?s_id=56

Efficacy, safety and tolerability of an oral cannabis extract in the treatment of spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=63

Cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=81

Are oral cannabinoids safe and effective in refractory neuropathic pain?
http://www.cannabis-med.org/studies/...w.php?s_id=143

Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=82

Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=108

Cannabis based medicinal extract on refractory lower urinary tract dysfunction
http://www.cannabis-med.org/studies/...w.php?s_id=103

Analgesic effect of the cannabinoid analogue nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=203

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

Nabilone in the treatment of multiple sclerosis
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.
http://www.cannabis-med.org/studies/...how.php?s_id=2

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.
http://www.cannabis-med.org/studies/...how.php?s_id=1

Tetrahydrocannabinol for tremor in multiple sclerosis.
http://www.cannabis-med.org/studies/...how.php?s_id=9

Marihuana as a therapeutic agent for muscle spasm or spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=53

Cannabis-based medicine in spasticity caused by multiple sclerosis.
http://www.unboundmedicine.com/medli...iple_sclerosis

Cannabis based treatments for neuropathic and multiple sclerosis-related pain.
http://www.unboundmedicine.com/medli...s_related_pain

The effect of cannabis on urge incontinence in patients with multiple sclerosis
http://www.unboundmedicine.com/medli...al__CAMS_LUTS_

Can Cannabis Help Multiple Sclerosis? An International Debate Rages
http://www.pacifier.com/~alive/cmu/c...is_help_ms.htm

Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease
http://www.illinoisnorml.org/index2....o_pdf=1&id=104

The endocannabinoid system is dysregulated in multiple sclerosis
http://brain.oxfordjournals.org/cgi/...tract/awm160v1

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/...ll/126/10/2191

Cannabis could hold the key to ending multiple sclerosis misery
http://www.physorg.com/news94743932.html

Cuppa Gives A Better 'ooh'
http://www.thehempire.com/index.php/...s_a_better_ooh

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/...ct/126/10/2191

Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cannabinoid control of neuroinflammation related to multiple sclerosis.
http://marijuana.researchtoday.net/a.../4/10/1400.htm

Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite
http://www.sciencedirect.com/science...e473322a24e5bf

The use of cannabinoids in MS: is it evidence based?
http://www.ukcia.org/research/UseOfC...denceBased.pdf

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
http://www.ukcia.org/research/WholeP...icSymptoms.pdf

Emerging properties of Cannabinoid medicines in the management of MS
http://www.ukcia.org/research/Manage...eSclerosis.pdf

Cannabis use in Spanish patients with multiple sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Cannabis May Halt Progression Of Multiple Sclerosis
http://norml.org/index.cfm?Group_ID=7704

Cannabinoid control of neuroinflammation related to multiple sclerosis
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

MRSA

Antibacterial Cannabinoids from Cannabis sativa
http://pubs.acs.org/cgi-bin/sample.c...np8002673.html

Killing bacteria with cannabis
http://arstechnica.com/journals/scie...-with-cannabis

Chemicals in Marijuana May Fight MRSA
http://www.webmd.com/news/20080904/m...may-fight-mrsa

Marijuana Ingredients Show Promise In Battling Superbugs
http://www.medicalnewstoday.com/articles/120477.php

How pot may win the war against super-bacteria
http://healthcare.zdnet.com/?p=1324

New medical uses found for marijuana
http://cannabisnews.com/news/24/thread24167.shtml

NABILONE

GENERIC NAME: NABILONE - ORAL (NAB-ih-lone)
Brand Names : Cesamet
http://www.medicinenet.com/nabilone-oral/article.htm

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Nabilone versus prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone
http://www.cannabis-med.org/studies/...w.php?s_id=129

Comparison of nabilone and prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=128

Nabilone vs. prochlorperazine for refractory emesis
http://www.cannabis-med.org/studies/...w.php?s_id=146

Nabilone vs. placebo
http://www.cannabis-med.org/studies/...w.php?s_id=156

Effects of nabilone and prochlorperazine on chemotherapy-induced emesis
http://www.cannabis-med.org/studies/...w.php?s_id=131

Superiority of nabilone over prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=126

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Effect of nabilone on nausea and vomiting after total abdominal hysterectomy
http://www.cannabis-med.org/studies/...w.php?s_id=137

Nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Synthetic cannabinomimetic nabilone on patients with chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=197

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
http://www.cannabis-med.org/studies/...w.php?s_id=153

Nabilone in the treatment of multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Analgesic effect of the cannabinoid analogue nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=203

Nabilone in the treatment of multiple sclerosis
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
http://www.cannabis-med.org/studies/...w.php?s_id=130

Nabilone and metoclopramide in the treatment of nausea and vomiting
http://www.cannabis-med.org/studies/...w.php?s_id=121

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Comparison of the antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
http://www.cannabis-med.org/studies/...w.php?s_id=129

Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain -
http://www.cannabis-med.org/studies/...w.php?s_id=197

Comparison of bronchial effects of nabilone and terbutaline
http://www.cannabis-med.org/studies/...ow.php?s_id=43

Nabilone Could Treat Chorea and Irritability in Huntington’s Disease
http://neuro.psychiatryonline.org/cg...18/4/553?rss=1

Cannabis Science: Nabilone reduced chronic pain caused by fibromyalgia
http://bbsnews.net/article.php/20071111150357312

Nabilone for the treatment of pain in fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/17974490

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

NAUSEA

THC improves appetite and reverses weight loss in AIDS patients
http://www.cannabis-med.org/studies/...w.php?s_id=189

Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

Nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
http://www.cannabis-med.org/studies/...w.php?s_id=180

Nausea relieved by tetrahydrocannabinol (dronabinol).
http://www.cannabis-med.org/studies/...ow.php?s_id=35

An efficient new cannabinoid antiemetic in pediatric oncology.
http://www.cannabis-med.org/studies/...how.php?s_id=7

Effect of nabilone on nausea and vomiting after total abdominal hysterectomy.
http://www.cannabis-med.org/studies/...w.php?s_id=137

Marijuana as antiemetic medicine
http://www.cannabis-med.org/studies/...w.php?s_id=134

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy
http://www.cannabis-med.org/studies/...ow.php?s_id=31

Inhalation marijuana as an antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=155

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
http://www.cannabis-med.org/studies/...w.php?s_id=120

Comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
http://www.cannabis-med.org/studies/...w.php?s_id=130

Nabilone and metoclopramide in the treatment of nausea and vomiting
http://www.cannabis-med.org/studies/...w.php?s_id=121

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Comparison of the antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
http://www.cannabis-med.org/studies/...w.php?s_id=129

THC or Compazine for the cancer chemotherapy patient--the UCLA study
http://www.cannabis-med.org/studies/...ow.php?s_id=34

Comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=128

Acute and subacute bronchial effects of oral cannabinoids.
http://www.cannabis-med.org/studies/...ow.php?s_id=44

Nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=146

Nabilone vs. placebo in chemotherapy-induced nausea and vomiting.
http://www.cannabis-med.org/studies/...w.php?s_id=156

Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine
http://www.cannabis-med.org/studies/...ow.php?s_id=30 delta 9-

Comparative trial of the antiemetic effects of THC and haloperidol
http://www.cannabis-med.org/studies/...ow.php?s_id=64

Comparison of delta-9-tetrahydrocannabinol and prochlorperazine.
http://www.cannabis-med.org/studies/...how.php?s_id=3

Tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.
http://www.cannabis-med.org/studies/...ow.php?s_id=88

Antiemetic effect of tetrahydrocannabinol
http://www.cannabis-med.org/studies/...how.php?s_id=6

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine
http://www.cannabis-med.org/studies/...ow.php?s_id=24

The antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis.
http://www.cannabis-med.org/studies/...w.php?s_id=131

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy
http://www.cannabis-med.org/studies/...how.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
http://www.cannabis-med.org/studies/...ow.php?s_id=23

THC as an antiemetic in patients treated with cancer chemotherapy
http://www.cannabis-med.org/studies/...ow.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC.
http://www.cannabis-med.org/studies/...w.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic
http://www.cannabis-med.org/studies/...w.php?s_id=126

Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy.
http://www.cannabis-med.org/studies/...how.php?s_id=4

Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids
http://www.unboundmedicine.com/medli...he_least_shrew

Mayo Study: Marijuana's THC Reduces Stomach Cramping
http://bbsnews.net/article.php/20061029211046523

THC effective in intractable nausea in a patient undergoing gastric bypass surgery
http://bbsnews.net/article.php/2008020313112065

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
http://www.medmjscience.org/Pages/science/chang.html

Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
http://haworthpress.com/store/Articl...t.asp?ID=18139

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac.
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

NEURONS/ BRAIN CELLS


Marijuana Promotes Neuron Growth
http://english.ohmynews.com/articlev...53377&rel_no=1

Marijuana-Like Chemicals in the Brain Calm Neurons
http://www.medpot.net/forums/index.php?showtopic=9686

Marijuana May Spur New Brain Cells
http://www.treatingyourself.com/vbul...ead.php?t=5921

Cannabinoids promote embryonic and adult hippocampus neurogenesis
http://www.jci.org/cgi/content/full/115/11/3104

NEUROPATHIC PAIN


Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain
http://www.redorbit.com/news/health/...ource=r_health

Cannabis-based medicine in central pain in multiple sclerosis
http://www.neurology.org/cgi/content.../65/6/812?etoc

Cannabis in painful HIV-associated sensory neuropathy
http://www.cannabis-med.org/studies/...w.php?s_id=199

Smoked cannabis therapy for HIV-related painful peripheral neuropathy
http://www.cannabis-med.org/studies/...w.php?s_id=172

Two cannabis based medicinal extracts for relief of central neuropathic pain
http://www.cannabis-med.org/studies/...w.php?s_id=143

Cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=82

Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain
http://www.cannabis-med.org/studies/...ow.php?s_id=85

Smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods.
http://www.cannabis-med.org/studies/...ow.php?s_id=96

Analgesic effect of the cannabinoid analogue nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=203

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Cannabis based treatments for neuropathic and multiple sclerosis-related pain.
http://www.unboundmedicine.com/medli...s_related_pain

Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
http://www.ukcia.org/research/WholeP...icSymptoms.pdf

Efficacy of 2 Cannabis based medicinal extracts for relief of central neuropathic pain
http://www.ukcia.org/research/Centra...inEfficacy.pdf

A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain.
http://marijuana.researchtoday.net/archive/5/6/1703.htm

Medicinal Marijuana Effective For Neuropathic Pain In HIV,
http://www.sciencedaily.com/releases...0806113135.htm

The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

NEUROPROTECTANT

Marijuana Protects Your Brain
http://www.roninpub.com/art-mjbrain.html

The neuroprotective effect of cannabinoids in a rat model of Parkinson's disease
(may need free registration)
http://www.medscape.com/medline/abstract/17196181

Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-THC
http://www.unboundmedicine.com/medli...el_of_Glaucoma

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
http://www.unboundmedicine.com/medli..._peroxynitrite

Neuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells
http://www.unboundmedicine.com/medli...l_in_AF5_cells

Cannabidiol has a cerebroprotective action
http://www.unboundmedicine.com/medli...ting_mechanism

Cannabidiol but not Delta(9)-THC has a neuroprotective effect without the development of tolerance..
http://www.unboundmedicine.com/medli...t_of_tolerance

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
http://www.unboundmedicine.com/medli...excitotoxicity

Cannabis and Neuroprotection
http://www.pacifier.com/~alive/cmu/c...protection.htm

Neuroprotection by Delta 9-THC against Ouabain-Induced In Vivo Excitotoxicity
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism
http://www.nature.com/bjp/journal/v1.../0707478a.html

The use of cannabinoids in MS: is it evidence based?
http://www.ukcia.org/research/UseOfC...denceBased.pdf

Neurons on Cannabinoids: Dead or Alive?
http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf

Cannabinoids and Brain Injury: Therapeutic Inplications
http://www.ukcia.org/research/Cannab...rainInjury.pdf

Cannabidiol and delta 9THC are neuroprotective antioxidants
http://www.ukcia.org/research/Neurop...tioxidants.pdf

Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

NUTRITION

Oily fish makes 'babies brainier' (hemp seed oil)
http://news.bbc.co.uk/2/hi/health/4631006.stm

Efficacy of dietary hempseed oil in patients with atopic dermatitis. (may need free registration)
http://www.medscape.com/medline/abst...yText=hempseed

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

Characterization, amino acid composition and in vitro digestibility of hemp (Cannabis) proteins
http://www.sciencedirect.com/science...a3209943890e39

HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (1)
http://www.ratical.org/renewables/hempseed1.html

HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (2)
http://www.ratical.org/renewables/hempseed2.html

Hemp seed oil: A source of valuable essential fatty acids
http://www.hempfood.com/IHA/iha03101.html

Occurrence of "omega-3" stearidonic acid in hemp seed
http://www.hempfood.com/IHA/iha03208.html

Hemp Seed Oil : The Wonder Oil For the New Millennium
http://www.ukcia.org/research/Happi/...Millennium.htm

Cannabis butter to spread across Europe
http://www.globalhemp.com/News/2004/...bis_butter.php

Hempseed as a nutritional resource: An overview
http://www.finola.com/HempseedNutrition.pdf

Hempseed: Nature's Perfect Food?
http://www.marijuanalibrary.org/HT_Hempseed_0492.html

Beta-caryophyllene is a dietary cannabinoid
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

OBSESSIVE COMPULSIVE DISORDER/ OCD

Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol
http://ajp.psychiatryonline.org/cgi/...full/165/4/536

OBESITY

Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
http://www.medscape.com/viewarticle/525040_print

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

ORGAN TRANSPLANTS

Marijuana Use in Potential Liver Transplant Candidates.
http://www.unboundmedicine.com/medli...nt_Candidates_

The debate about marijuana usage in transplant candidates: recent medical evidence on marijuana health effects
http://www.unboundmedicine.com/medli...ealth_effects_

OSTEOPOROSIS/ BONES


Prototype drug to prevent osteoporosis based on cannabinoids
http://www.news-medical.net/?id=15220

Hebrew U. Researchers Find Cannabis Can Strengthen Bones
http://www.israelnationalnews.com/News/News.aspx/96146

Peripheral cannabinoid receptor, CB2, regulates bone mass
http://www.pnas.org/cgi/content/abstract/103/3/696

New Weapon In Battle Against Osteoporosis
http://www.medicalnewstoday.com/articles/35621.php

Activation of CB2 receptor attenuates bone loss in osteoporosis
http://www.cannabis-med.org/english/...l.php?id=210#2

Cannabis-like compound prevents bone loss
http://www.thehempire.com/index.php/...ents_bone_loss

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling
http://lib.bioinfo.pl/auth:Yirmiya,R

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.
http://www.unboundmedicine.com/medli...titis_in_rats_

PAIN

Cannabis effective at relieving pain after major surgery
http://www.news-medical.net/?id=17995

Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect
http://www.medjournal.com/forum/show...87&postcount=1

Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain,
http://www.redorbit.com/news/health/...ource=r_health

Cannabinoid analgesia as a potential new therapeutic option (may need free registration)
http://www.medscape.com/medline/abstract/16449552

Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain
http://www.cannabis-med.org/studies/...w.php?s_id=184

Delta-9-THC based monotherapy in fibromyalgia patients
http://www.cannabis-med.org/studies/...w.php?s_id=194

Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain -
http://www.cannabis-med.org/studies/...w.php?s_id=197

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.
http://www.cannabis-med.org/studies/...w.php?s_id=178

Are oral cannabinoids safe and effective in refractory neuropathic pain?
http://www.cannabis-med.org/studies/...w.php?s_id=143

Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Cannabis use for chronic non-cancer pain
http://www.cannabis-med.org/studies/...ow.php?s_id=91

Tetrahydrocannabinol for treatment of chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=147

Analgesic effect of the cannabinoid analogue nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=203

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Pain relief with oral cannabinoids in familial Mediterranean fever.
http://www.cannabis-med.org/studies/...ow.php?s_id=18

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

Marihuana as a therapeutic agent for muscle spasm or spasticity.
http://www.cannabis-med.org/studies/...ow.php?s_id=53

Analgesic effect of delta-9-tetrahydrocannabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

Most pain patients gain benefit from cannabis in a British study
http://www.cannabis-med.org/english/...el.php?id=84#1

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
http://marijuana.researchtoday.net/archive/4/8/1384.htm

Cannabis: Use in HIV for Pain and Other Medical Symptoms
http://www.sciencedirect.com/science...ca04d8bd433c52

Ajulemic acid: A novel cannabinoid produces analgesia without a “high”
http://www.sciencedirect.com/science...cea7fb6b9bd2a5

Therapeutic Aspects of Cannabis and Cannabinoids
http://www.ukcia.org/research/Thereputic/Therapeut.htm

Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms?
http://www.ukcia.org/research/WholeP...icSymptoms.pdf

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

NOVEL SYNERGISTIC OPIOID-CANNABINOID CODRUG FOR PAIN MANAGEMENT
http://www.wipo.int/pctdb/en/wo.jsp?WO=2008045556

Nabilone for the treatment of pain in fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/17974490

Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.
http://www.cannabis-med.org/studies/...w.php?s_id=148

Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

PANCREATITIS

Cannabinoids ameliorate pain and reduce disease pathology in cerulein -induced acute pancreatitis
http://ccicnewsletter.com/index.php?...#_Toc177908961

Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells
http://www.pubmedcentral.nih.gov/art...rtype=abstract

PARKINSON'S DISEASE


Marijuana Compounds May Aid Parkinson's Disease
http://cannabisnews.com/news/19/thread19725.shtml

Marijuana-Like Chemicals Helps Treat Parkinson's
http://cannabisnews.com/news/22/thread22608.shtml

Cannabis use in Parkinson's disease: subjective improvement of motor symptoms.
http://www.cannabis-med.org/studies/...ow.php?s_id=33

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease
http://www.cannabis-med.org/studies/...ow.php?s_id=54

Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
http://www.cannabis-med.org/studies/...w.php?s_id=153

Evaluation of cannabidiol in dystonic movement disorders.
http://www.cannabis-med.org/studies/...ow.php?s_id=14

Beneficial and adverse effects of cannabidiol in a Parkinson patient
http://www.cannabis-med.org/studies/...w.php?s_id=142

Neuroprotective effect of cannabinoids in a rat model of Parkinson's disease
(may need free registration)
http://www.medscape.com/medline/abstract/17196181

Cannabinoids in parkinsonism (3 abstracts)
http://www.mdvu.org/emove/article.asp?ID=586

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

PATENTS RELATED TO CANNABIS

US Patent 7344736 - Extraction of pharmaceutically active components from plant materials
http://www.patentstorm.us/patents/7344736/fulltext.html

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery
http://www.patentstorm.us/patents/6328992.html

US Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment
http://www.patentstorm.us/patents/6949582/fulltext.html

US Patent 7402686 - Cannabinoid crystalline derivatives and process of cannabinoid purification
http://www.patentstorm.us/patents/7402686/fulltext.html

US Patent 6713048 - Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use
http://www.patentstorm.us/patents/6713048/fulltext.html

US Patent 6974568 - Treatment for cough
http://www.patentstorm.us/patents/6974568/fulltext.html

US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
http://www.patentstorm.us/patents/7088914/fulltext.html

US Patent 7399872 - Conversion of CBD to Δ-THC and Δ-THC
http://www.patentstorm.us/patents/7399872/fulltext.html

US Patent 6383513 - Compositions comprising cannabinoids (nasal spray)
http://www.patentstorm.us/patents/6383513/fulltext.html

US Patent 6132762 - Transcutaneous application of marijuana
http://www.patentstorm.us/patents/6132762.html

US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma
http://www.patentstorm.us/patents/4189491.html

POST TRAUMATIC STRESS DISORDER

IDF TO TREAT SHELL SHOCK WITH CANNABIS
http://www.safeaccessnow.org/article.php?id=1324

Study: Marijuana Eases Traumatic Memories
http://cannabisnews.com/news/13/thread13601.shtml

Medical Marijuana: PTSD Medical Malpractice
http://salem-news.com/articles/june1...eque_61407.php

Cannabis for the Wounded - Another Walter Reed Scandal
http://www.libertypost.org/cgi-bin/r...179973&Disp=11

PTSD and Cannabis: A Clinician Ponders Mechanism of Action
http://ccrmg.org/journal/06spr/perspective2.html

Cannabis Eases Post Traumatic Stress
http://ccrmg.org/journal/06spr/ptsd.html

Endocannabinoids extinguish bad memories in the brain
http://www.cannabis-med.org/english/...l.php?id=123#1

Natural high helps banish bad memories
http://www.newscientist.com/article/...-memories.html

PREGNANCY

Oily fish makes 'babies brainier'
http://news.bbc.co.uk/2/hi/health/4631006.stm

Ganja use among Jamaican women.
http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

Dreher's Jamaican Pregnancy Study
http://www.november.org/stayinfo/bre...eherStudy.html

Cannabis Relieves Morning Sickness
http://ccrmg.org/journal/06spr/dreher.html#morning

Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica
http://www.druglibrary.org/Schaffer/...can-babies.htm

The Endocannabinoid-CB Receptor System
http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf

CLAIM #7: MARIJUANA USE DURING PREGNANCY HARMS THE FETUS
http://www.erowid.org/plants/cannabi...is_myth7.shtml

More Pregnancy Highs Than Lows
http://www.thehempire.com/index.php/...ighs_than_lows

Medicinal cannabis use among childbearing women
http://www.sciencedirect.com/science...6e05c3d76bf72d

Use of anti-emetic herbs in pregnancy: women's choices, and the question of safety and efficacy
http://www.sciencedirect.com/science...bb724ac8061090

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

PRENATAL EXPOSURE

Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica
http://www.druglibrary.org/Schaffer/...can-babies.htm

The Endocannabinoid-CB Receptor System
http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf

Ganja use among Jamaican women.
http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

Dreher's Jamaican Pregnancy Study
http://www.november.org/stayinfo/bre...eherStudy.html

Nonmutagenic action of cannabinoids in vitro
http://content.karger.com/ProdukteDB...asp?Doi=136789

Prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth.
http://www.ncbi.nlm.nih.gov/sites/en...t_uids=3657756

Tobacco and marijuana use on offspring growth from birth through 3 years of age.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Prenatal marijuana use and neonatal outcome.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats
http://www.sciencedirect.com/science...f093e0645f5df2

Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?
http://haworthpress.com/store/Articl...t.asp?ID=18139

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

PRIONS

Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity
http://www.jneurosci.org/cgi/content...act/27/36/9537

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease)
http://bbsnews.net/article.php/20070916110536662




PRURITIS

Cream with endocannabinoids effective in the treatment of pruritus
http://bbsnews.net/article.php/20051211212223236/print

Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus.
http://www.cannabis-med.org/studies/...w.php?s_id=196

Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
http://www.cannabis-med.org/studies/...w.php?s_id=116

QUITTING OTHER DRUGS

Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica (cocaine)
http://www.cannabis-med.org/studies/...w.php?s_id=260

Role of cannabinoid receptors in alcohol abuse
http://www.medicalnewstoday.com/articles/30338.php

Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

Cannabis substitution "(alcohol)
http://www.cannabis-med.org/studies/...ow.php?s_id=86

Cannabis as a Substitute for Alcohol
http://ccrmg.org/journal/03sum/substitutealcohol.html

SAFETY

Proven: Cannabis is safe medicine
http://www.ukcia.org/research/safe-medicine.htm

Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Medical use of cannabinoids does not cause an increase in serious adverse health effects
http://www.cmaj.ca/cgi/content/full/178/13/1685

Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated
http://www.sciencedaily.com/releases...0617125751.htm

Alcohol and cannabis use as risk factors for injury - a case-crossover analysis in a Swiss hospital emergency department
http://www.biomedcentral.com/1471-2458/9/40

SAFETY-ADULTERANTS

Smoke Pot, Get Lead Poisoning? (Germany/Europe)
http://www.webmd.com/news/20080409/s...lead-poisoning

Neuropsychological effects of formaldehyde use
http://www.unboundmedicine.com/medli...maldehyde_use_

Microbiological contaminants of marijuana
http://www.hempfood.com/IHA/iha01205.html

Paraquat and marijuana: epidemiologic risk assessment.
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

SATIVEX

Questions and Answers About SATIVEX® Liquid Medical Marijuana
http://www.mpp.org/library/questions...al-mariju.html

Sativex in the treatment of pain caused by rheumatoid arthritis
http://rheumatology.oxfordjournals.o. ..stract/45/1/50

Sativex produced significant improvements in a subjective measure of spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=170

Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
http://www.cannabis-med.org/studies/...w.php?s_id=168

Sativex showed positive effects in 65 per cent of patients with chronic diseases
http://www.cannabis-med.org/english/...l.php?id=230#4

Cannabis; adverse effects from an oromucosal spray.
http://lib.bioinfo.pl/pmid:17703180

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
http://marijuana.researchtoday.net/archive/4/8/1384.htm

Sativex successfully treats neuropathic pain characterised by allodynia
http://www.sciencedirect.com/science...143cfe474843b1

Conditional okay for cannabis prescription drug
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

SCHIZOPHRENIA/ MENTAL DISORDERS

Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia.
(may need free registration)
http://www.medscape.com/medline/abstract/16710682

Symptoms of schizotypy precede cannabis use.
http://www.ukcia.org/forum/read.php?7,7543,7579

Cannabidiol as an antipsychotic
http://www.cannabis-med.org/studies/...w.php?s_id=171

Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients
http://www.unboundmedicine.com/medli...f_cannabis_use

Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
http://www.unboundmedicine.com/medli..._and_Cognition

Cannabis is a First-Line Treatment for Childhood Mental Disorders
http://www.counterpunch.org/mikuriya07082006.html

Cannabis does not induce schizophrenia,
http://www.medicalnewstoday.com/articles/12283.php

Cannabis use does not cause schizophrenia
http://www.health.am/psy/more/cannab...schizophrenia/

Cannabinoids and psychosis.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Cannabis as a psychotropic medication
http://bjp.rcpsych.org/cgi/content/full/185/1/78

Study Shows Long Term Marijuana Users Healthy
http://www.erowid.org/plants/cannabi...science3.shtml

Cannabis and schizophrenia link blurs further
http://www.newscientist.com/channel/...s-further.html

Evidence does not show a strong causal relation between the use of cannabis and psychosocial harm
http://www.library.nhs.uk/mentalHeal...4106&tabID=289

No Increased Schizophrenia Risk With Use Of Cannabis
http://www.thehempire.com/index.php/...se_of_cannabis

Recipe For Trouble (anecdotal)
http://www.cbsnews.com/stories/2002/...in503022.shtml

Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.
http://www.cannabis-med.org/studies/...ern=ANXIOLYTIC

Cannabis and psychosis
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

The Mental Health Risks of Adolescent Cannabis Use
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

SICKLE CELL DISEASE

Sickle Cell Disease and Cannabis
http://www.pacifier.com/~alive/cmu/Sickle_cell.htm

Marijuana smoking in young adults with sickle cell
http://www.illinoisnorml.org/content/view/309/

Medical use of cannabis in sickle cell disease
http://www.chanvre-info.ch/info/it/M...in-sickle.html

Cannabis use in sickle cell disease: a questionnaire study.
http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract

SLEEP MODULATION

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
http://www.medscape.com/medline/abst...44117?prt=true

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

Cannabis-based medicine in central pain in multiple sclerosis.
http://www.cannabis-med.org/studies/...w.php?s_id=175

Two cannabis based medicinal extracts for relief of central neuropathic pain
http://www.cannabis-med.org/studies/...ow.php?s_id=15

Functional role for cannabinoids in respiratory stability during sleep
http://www.pacifier.com/~alive/cmu/c...leep_apnea.htm

THC reduces sleep apnoea in animal research
http://www.cannabis-med.org/english/...l.php?id=120#1

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
http://marijuana.researchtoday.net/archive/4/8/1384.htm

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
http://marijuana.researchtoday.net/archive/4/8/1234.htm

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.
http://www.ncbi.nlm.nih.gov/pubmed/1...t=AbstractPlus

The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
http://www.unboundmedicine.com/medli...nducing_agent_

SMOKED CANNABIS AS A MEDICATION

Fitness to drive in spite (because) of THC
http://www.unboundmedicine.com/medli...use__of_THC%5D

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

Effects of smoked marijuana in experimentally induced asthma.
http://www.cannabis-med.org/studies/...ow.php?s_id=57

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
http://www.ukcia.org/research/Smoked...nAsthmatic.php

The effects of smoked cannabis in painful peripheral neuropathy
http://www.cannabis-med.org/studies/...ow.php?s_id=96

Inhalation marijuana as an antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=155

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Epilepsy patients are smoking pot
http://www.safeaccessnow.org/article.php?id=1638

Anticonvulsant nature of marihuana smoking
http://www.cannabis-med.org/studies/...ow.php?s_id=39

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
http://archopht.ama-assn.org/cgi/con...ct/116/11/1433

Marihuana smoking and intraocular pressure.
http://www.cannabis-med.org/studies/...ow.php?s_id=47

CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE
http://www.druglibrary.org/schaffer/hemp/migrn2.htm

Marinol vs Natural Cannabis
http://www.norml.org/pdf_files/NORML...l_Cannabis.pdf

Smoked cannabis therapy for HIV-related painful peripheral neuropathy
http://www.cannabis-med.org/studies/...w.php?s_id=172

Smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods.
http://www.cannabis-med.org/studies/...ow.php?s_id=96

Marijuana smoking in young adults with sickle cell
http://www.illinoisnorml.org/content/view/309/

Medical use of cannabis in sickle cell disease
http://www.chanvre-info.ch/info/it/M...in-sickle.html

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac.
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

Evaluation of herbal cannabis characteristics by medical users: a randomized trial
http://www.pubmedcentral.nih.gov/art...medid=17101054

Chronic Cannabis Use in the Compassionate Investigational New Drug Program
http://www.letfreedomgrow.com/cmu/ch...nnabis_use.htm

SOCIAL ADJUSTMENT


Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Marijuana use motives and social anxiety among marijuana-using young adults.
http://marijuana.researchtoday.net/archive/4/8/1303.htm

SPASTICITY

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=166

Cannabis-based medicine in spasticity caused by multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=192

Cannabinoids in multiple sclerosis
http://www.cannabis-med.org/studies/...w.php?s_id=160

Sativex produced significant improvements in a subjective measure of spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=170

Do cannabis-based medicinal extracts have general or specific effects on symptoms in ms?
http://www.cannabis-med.org/studies/...ow.php?s_id=56

Efficacy, safety and tolerability of an oral cannabis extract in the treatment of spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=63

Are oral cannabinoids safe and effective in refractory neuropathic pain?
http://www.cannabis-med.org/studies/...w.php?s_id=143

Experiences with THC-treatment in children and adolescents
http://www.cannabis-med.org/studies/...ow.php?s_id=80

The treatment of spasticity with D9-THC in patients with spinal cord injury
http://www.cannabis-med.org/studies/...ow.php?s_id=79

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

Nabilone in the treatment of multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Treatment of spasticity in spinal cord injury with dronabinol
http://www.cannabis-med.org/studies/...w.php?s_id=112

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
http://www.cannabis-med.org/studies/...ow.php?s_id=10

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.
http://www.cannabis-med.org/studies/...how.php?s_id=2

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.
http://www.cannabis-med.org/studies/...how.php?s_id=1

Effect of Delta-9-THC on EMG Measurements in Human Spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=110

The effect of delta-9-THC on human spasticity.
http://www.cannabis-med.org/studies/...w.php?s_id=154

Cannabis effect on spasticity in spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=113

Treatment of human spasticity with delta 9-tetrahydrocannabinol.
` http://www.cannabis-med.org/studies/...how.php?s_id=8

Marihuana as a therapeutic agent for muscle spasm or spasticity.
http://www.cannabis-med.org/studies/...ow.php?s_id=53

The perceived effects of marijuana on spinal cord injured males.
http://www.cannabis-med.org/studies/...w.php?s_id=138

Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.
http://www.unboundmedicine.com/medli...er_mutant_mice

Cannabis-based medicine in spasticity caused by multiple sclerosis
http://www.unboundmedicine.com/medli...iple_sclerosis

Nabilone significantly reduces spasticity-related pain
http://www.unboundmedicine.com/medli...ss_over_trial_

SPINAL CORD INJURY

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=166

Are oral cannabinoids safe and effective in refractory neuropathic pain?
http://www.cannabis-med.org/studies/...w.php?s_id=143

The treatment of spasticity with D9-THC in patients with spinal cord injury
http://www.cannabis-med.org/studies/...ow.php?s_id=79

Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
http://www.cannabis-med.org/studies/...w.php?s_id=102

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

Treatment of spasticity in spinal cord injury with dronabinol
http://www.cannabis-med.org/studies/...w.php?s_id=112

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
http://www.cannabis-med.org/studies/...ow.php?s_id=10

The effect of delta-9-THC on human spasticity.
http://www.cannabis-med.org/studies/...w.php?s_id=154

Cannabis effect on spasticity in spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=113

Marihuana as a therapeutic agent for muscle spasm or spasticity.
http://www.cannabis-med.org/studies/...ow.php?s_id=53

The perceived effects of marijuana on spinal cord injured males.
http://www.cannabis-med.org/studies/...w.php?s_id=138

STROKE

Cannabidiol has a cerebroprotective action
http://www.unboundmedicine.com/medli...ting_mechanism

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the...l_marijua.html

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

TEA AS MEDICINE

Cannabis tea revisited: A systematic evaluation
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Cuppa Gives A Better 'ooh'
http://www.thehempire.com/index.php/...s_a_better_ooh

With the use of cannabis tea only a small proportion of THC in the cannabis is ingested
http://www.ohiopatient.net/v2/content/view/906/37/

THC/ TETRAHYDROCANNABINOL

THC is effective in the treatment of tics in Tourette syndrome
http://www.cannabis-med.org/studies/...ow.php?s_id=98

THC effective in Tourette-Syndrome
http://www.pacifier.com/~alive/cmu/tourette_thc.htm

THC effective in Tourette syndrome in a 6-week trial
http://www.cannabis-med.org/english/...l.php?id=146#1

Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
http://ajp.psychiatryonline.org/cgi/...full/156/3/495

THC inhibits primary marker of Alzheimer's disease
http://www.cannabis-med.org/english/...l.php?id=225#3

THC improves appetite and reverses weight loss in AIDS patients
http://www.cannabis-med.org/studies/...w.php?s_id=189

Cancer-related anorexia-cachexia syndrome
http://www.unboundmedicine.com/medli...ia_Study_Group

THC effective in appetite and weight loss in severe lung disease (COPD)
http://www.cannabis-med.org/english/...l.php?id=191#2

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
http://www.unboundmedicine.com/medli...inoid_receptor

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
http://www.unboundmedicine.com/medli..._arthritic_rat

Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
http://www.cannabis-med.org/studies/...w.php?s_id=109

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
http://www.cannabis-med.org/studies/...ow.php?s_id=60

Effects of smoked marijuana in experimentally induced asthma.
http://www.cannabis-med.org/studies/...ow.php?s_id=57

Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
http://www.cannabis-med.org/studies/...ow.php?s_id=67

New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
http://www.medicalnewstoday.com/articles/22937.php

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
http://www.ukcia.org/research/Smoked...nAsthmatic.php

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
http://www.cannabis-med.org/studies/...w.php?s_id=193

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
http://cancerres.aacrjournals.org/cg...act/66/13/6615

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
http://www.cannabis-med.org/english/...l.php?id=219#1

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
http://mcr.aacrjournals.org/cgi/cont...stract/4/8/549

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the...l_marijua.html

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
http://www.cannabis-med.org/studies/...ow.php?s_id=10

The effect of delta-9-THC on human spasticity.
http://www.cannabis-med.org/studies/...w.php?s_id=154

The treatment of spasticity with D9-THC) in patients with spinal cord injury
http://www.cannabis-med.org/studies/...ow.php?s_id=79

Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
http://www.cannabis-med.org/studies/...w.php?s_id=102

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=166

Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
http://www.unboundmedicine.com/medli..._and_Cognition

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

Marihuana as a therapeutic agent for muscle spasm or spasticity.
http://www.cannabis-med.org/studies/...ow.php?s_id=53

Analgesic effect of delta-9-tetrahydrocannabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Cannabis use for chronic non-cancer pain
http://www.cannabis-med.org/studies/...ow.php?s_id=91

Tetrahydrocannabinol for treatment of chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=147

Delta-9-THC based monotherapy in fibromyalgia patients
http://www.cannabis-med.org/studies/...w.php?s_id=194

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
http://www.unboundmedicine.com/medli...excitotoxicity

THC effective in intractable nausea in a patient undergoing gastric bypass surgery
http://bbsnews.net/article.php/2008020313112065

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
http://www.medmjscience.org/Pages/science/chang.html


Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol
http://www.pubmedcentral.nih.gov/art...?artid=2279017

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Effects of marihuana in laboratory animals and in man
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

THC ACID/ THCA

Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.
http://marijuana.researchtoday.net/archive/4/8/1331.htm

TETRAHYDROCANNABOVARIN/ THCV

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

Plant cannabinoids: a neglected pharmacological treasure trove
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez

TOBACCO VS CANNABIS


Cannabis Smoke and Cancer: Assessing the Risk
http://www.norml.org/index.cfm?Group_ID=6891

Cannabis and tobacco smoke are not equally carcinogenic
http://www.pubmedcentral.nih.gov/art...?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer
http://www.mapinc.org/drugnews/v05/n1065/a03.html

Tobacco and marijuana use on offspring growth from birth through 3 years of age.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Progression from marijuana use to daily smoking and nicotine dependence
http://www.erowid.org/references/refs_view.php?ID=6951

High anxieties - What the WHO doesn't want you to know about cannabis
http://www.newscientist.com/article/...-cannabis.html

Radioactive tobacco
http://www.cannabisculture.com/news/tobacco/

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Cannabis use when it's legal
http://www.sciencedirect.com/science...96c8de7949a364

Aluminum in Tobacco and Cannabis and Smoking-Related Disease
http://www.sciencedirect.com/science...14cf03f3b4bc4e

Marijuana Improves Fertility in Tobacco Smokers
http://news.softpedia.com/news/Marij...rs-41535.shtml

TOLERANCE

A Molecular Basis of Analgesic Tolerance to Cannabinoids
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

TOURETTE'S SYNDROME

Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol
http://ajp.psychiatryonline.org/cgi/...full/156/3/495

THC is effective in the treatment of tics in Tourette syndrome
http://www.cannabis-med.org/studies/...ow.php?s_id=98

Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol
http://www.cannabis-med.org/studies/...ow.php?s_id=99

Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome.
http://www.cannabis-med.org/studies/...w.php?s_id=100

THC effective in Tourette-Syndrome
http://www.pacifier.com/~alive/cmu/tourette_thc.htm

THC effective in Tourette syndrome in a 6-week trial
http://www.cannabis-med.org/english/...l.php?id=146#1

Cannabinoids reduce symptoms of Tourette's syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1...,f1000m,isrctn

Effective treatment of Tourette’s syndrome with marijuana.
http://www.cannabis-med.org/studies/...rn=INTERACTION

ULCERATIVE COLITIS- see CROHN'S

VISION- see GLAUCOMA

VAPORIZERS

Vaporization as a smokeless cannabis delivery system
http://www.cannabis-med.org/studies/...w.php?s_id=187

Smokeless Cannabis Delivery Device Efficient And Less Toxic
http://www.medicalnewstoday.com/articles/71112.php

Volcano is to Vaporizer As Porsche is to Automobile
http://ccrmg.org/journal/04spr/volcano.html

Recommendation to Patients: "Don’t smoke, Vaporize"
http://ccrmg.org/journal/03sum/vaporize.html

Decreased respiratory symptoms in cannabis users who vaporize.
http://marijuana.researchtoday.net/archive/4/4/1195.htm

Use of vaporizers reduces toxins from cannabis smoke
http://www.cannabis-med.org/english/...l.php?id=146#2

Marijuana Water Pipe and Vaporizer Study
http://www.ukcia.org/research/pipes.htm

Effect of intrapulmonary tetrahydrocannabinol administration in humans.
http://marijuana.researchtoday.net/archive/5/8/1816.htm

US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
http://www.patentstorm.us/patents/7088914/fulltext.html

WILSON'S DISEASE

Cannabis sativa and dystonia secondary to Wilson's disease. (may need free registration)
http://www.medscape.com/medline/abstract/15390041

WITHDRAWAL SYNDROME


Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Pot, Tobacco Withdrawal Equally Rough
http://www.webmd.com/mental-health/n...-equally-rough

A Within-Subject Comparison of Withdrawal Symptoms During Abstinence From Cannabis, Tobacco, and Both Substances
http://www.pubmedcentral.nih.gov/art...tool=pmcentrez
 

madhu

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#6
Arm
You need a one year fellowship to read and digest all those articles. Marijuana genie is like credit inflation, once the genie is out it cannot put back into the bottle
 

FunnyMoney

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#7
After seeing all those links, I don't think there's enough earth to dig the rabbit hole deeper. Somebody's likely to sue big pharma.
 

arminius

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#8
Big pharm, like the deep state is coming to a abrupt cliff with their lies. More and more folks are seeing through their Bs.

But fear is a powerful thing.
 

nickndfl

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#9
If it really was a silver bullet for cancer, don't you think George Carlin would still be alive?
 

FunnyMoney

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#10
I found this quite interesting among the links provided.

I had this vision where I could return to my days as a kid eating quarter pound hamburgers for dinner and ice cream for desert 10 times a week. Is it possible,,, LOL.... not likely but maybe chickenburgers and tofu ice cream.

Here's what triggered my wishful thinking...



Medical marijuana: study shows that THC slows atherosclerosis

THC, or delta-9-tetrahydrocannabinol, is one of the many cannabinoids in marijuana. Cannabinoids have been shown to be medically beneficial as analgesics and anti-nausea agents, among other findings.

Most recently, Swiss and German researchers have shown that a very small dose of THC slows the progression of atherosclerosis (clogging of the arteries) in mice. It's a pretty amazing study, especially since atherosclerosis is the leading cause of heart disease, and strokes, in the world.

Look below the fold for details.,,,

From: http://thenexthurrah.typepad.com/the_next_hurrah/2005/04/medical_marijua.html
 

mayhem

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#11
A whole lot of proof, and you will still look at stripped sunshine in most states if cought with it.

Also all this proof was done under super controlled conditions, not my kitchen. Not like just popping a bud in a pipe and toking it. Also quality control is a issue. My neighbors buds are probably far different that what they used in all their research.

As long as someone can plant a seed in the ground, big pharma won't touch it and it will always be illegal to the feds. Ya gotta follow the money guys.

I'm all for legalized weed. But for now it looks like we are trying to push the toothpaste back into the tube. As it stands right now it is a cure for the wealthy, those who can afford it. Most people who have cancer couldn't afford to use it at today's prices.

Also I have no clue as to wither it is curing me or not. I have had 5 years worth of radiation just from CT scans in the last 3 months. So how can I monitor it without causing more cancer from the scans?
 

Silver

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#12
I've smoked it off and on for 48 years - it's not the panacea for everything. It has a lot of downsides also. If you live a healthy lifestyle, you're better off without it. It does have therapeutic properties, but all this miracle shit is hype. It's good for wasting issues from drug treatments (appetite), it's good for mild insomnia, mild depression (short term). It's also good for getting your ass thrown in jail.