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This Week's Health Update

Alton

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This just in...Psychiatry is BULLSHIT! Bulls were befuddled!
Proven Wrong About Many of Its Assertions, Is Psychiatry Bullsh*t? | Alternet

The Germans chime in...
German Psychologists Declare “the Drugs Don’t Work”

Meanwhile, back in the good ol' USofA...
Big Pharma Spent Nearly $1 Billion Lobbying Government to Push Opiates

From the British desk comes the news that...
Enzymes used in cleaning products and food 'are potent allergens', warns study | Environment | The Guardian

For this week's in-depth report...
Fungus in humans identified for first time as key factor in Crohn's disease -- ScienceDaily
Reading the related articles in the right sidebar at the above link is highly recommended
 

GOLDBRIX

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I think since a GERMAN PSYCHOLOGIST "chimed in" I think that he has a bone to pick with the older medical art of PSYCHAITRY.

.gov hires more psychologists CHEAPER than hiring one psychiatrist. Psychologists use to have to work UNDER a Psychiatrist and the Psychiatrist would be the one who would be responsible for prescribing the true mood / mental altering drugs and long term treatments.
Psychologist would handle group therapy sessions.
I view Psychologist as I do Social Workers - Make Work Professions - Claim to Identify a Disorder ( MSW - problem) then offer to "treat it" .

Psychologists have a box or boxes for EVERY type of individual in the World. Even if you have zero psychological issues they have a term for that too. aka - Make Work.
 

Alton

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Perhaps, however, The Diagnostic and Statistical Manual of Mental Disorders stands as proof positive that the "profession" of psychiatry is pure, unadulterated, 100% bullshit.

This does not mean that some people don't need mental help. It simply means that psychiatry as is practised today is NOT the means of getting that help.
 

GOLDBRIX

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Psychology chases the same witches and demons.
I had an aunt who began having mental issues.
A psychiatrist ordered blood work after she had no changes under her psychologist treatment and therapies.

Come founded out due to obsession with eating hotdogs her levels were outside of normal ranges. The psychiatrist told her to eat bananas, if she drank soft drinks to drink Coca-Cola, and placed her on Lithium for a time being.
His treatment and protocol worked for her.

Of the Pair-a-Docs ( see the play on the word) I trust a psychiatrist over psychologist. IMO
 

Alton

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Fluoroquinolones - Class of antibiotics (see: Cipro, Levaquin, etc.). Known by FDA to be EXTREMELY dangerous to human health

“This antibiotic will ruin you” – A Woman Had to Undergo 20 Surgeries to Repair Damage This Common Drug Caused. (FDA issued a warning too late…) | AltHealthWorks.com

Excerpt from article:

Fluoroquinolones: The Most Dangerous Common Antibiotics on The Market

Fluoroquinolones is a class of antibiotics that can easily take the title of the most dangerous antibiotics available on the market.

These include:

-ciprofloxacin (Cipro)
-levofloxacin (Levaquin)
-moxifloxacin (Avelox)
-ofloxacin (Floxin)
-gemifloxacin (Factive)
-plus generic brands

On July 26, 2016 the U.S. Food and Drug administration (FDA) revised the warning for these antibiotics to the strongest possible FDA warning.

“These medicines are associated with disabling and potentially permanent side effects of the tendons, muscles, joints, nerves, and central nervous system that can occur together in the same patient.”

This serious warning was due to fluoroquinolones’ seriously side effects and damage to:

Central nervous system: nerve damage, hallucinations, brain fog, psychosis, loss of memory, anxiety, depression, confusion, suicidal thoughts, and even personality changes

Musculoskeletal and peripheral nervous system: tendon rupture, tendinitis, numbness and tingling in arms and legs, muscle weakness and pain, joint pain and swelling

Visual system: retinal detachment

Renal system: kidney failure

Other body systems: skin rash, sunburn, abnormal heart beat, severe diarrhea

Many studies back up the warning:

Fluoroquinolone antibiotics have been associated with Achilles tendinitis and rupture in reports as early as 1992.

A 2010 report concluded that fluoroquinolones are associated with many musculoskeletal complications involving tendon, cartilage, bone, and muscle that are often underreported.

A 2003 review connected fluoroquinolones to tendon injuries, especially in patients with other existing health issues.
 

Alton

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The following medicines in the article are known generally as gabapentinoids. For those on pain meds these may well be on your prescription regemin:

Neurontin and Lyrica Adverse Effects: The Saga Continues | Health & Wellness News

Here's the main point but there's much supporting evidence att the link above:

Lyrica Use Injures Muscles and Induces Brain Shrinkage
A March 2017 animal study identified another scary adverse side effect from Lyrica or pregabalin. Animals were given either a single dose or a daily dose of varying amounts of pregabalin for 21 days. Immediately after the three weeks, skeletal muscle tissue was evaluated for injury and oxidative stress. Regardless of the dose, pathological damage was found. The worst damage occurred with long-term use, showing as a significant loss of muscle or muscle atrophy, and high levels of inflammatory cells infiltrating into the muscles. This led to cell degeneration after just 21 days of exposure to the drug. This is yet another example of “a death sentence to cells”. Many with chronic pain disorders are put on this drug for years. What is it doing to this population? The reason for the muscle damage is still unclear, but is the medical treatment causing more harm in the long-run?

It has been somewhat of a mystery on how Lyrica/pregabalin works. In a recent cellular study, scientists found that pregabalin decreased nerve excitation or nerve firing in the part of the brain called the dentate gyrus and cells called granule cells. In addition, Lyrica exposure caused these granule cells to mature or age faster. The dentate gyrus is in the input region or receiving area of the hippocampus, which plays a critical role in learning, memory, and spatial relationship interpretation. New nerve cells in this area are generated throughout all ages of life, but Lyrica was found to dampen or inhibit the rate of signals in the area and aged the granule cells. When nerve tissue is on-fire with inflammation and over-stimulation, it is one thing to dampen the hippocampus, but what about chronic use or inappropriate use of the drug. Is this a death sentence to hippocampal function?

Other new information showed that Lyrica treatment shrunk the brain’s gray matter in fibromyalgia patients treated with short-term use of Lyrica. The drug blocked the production of the excitatory neurotransmitter, glutamate. Excess glutamate is certainly problematic in the brain, as it leads to “wind-up” or central sensitization and causes high levels of oxidative stress to the brain. This is felt as pain, insomnia, depression, anxiety, etc. The authors of this study did not seem to find the brain shrinkage alarming, but rather helpful, because of reduced pain and less oxidative stress on the brain, but common sense begs to differ. The concern, again, relates to chronic use, as many fibromyalgia patients are put on this drug for years. It would seem to be a double-edge sword on brain size and stability, as Lyrica causes brain shrinkage and so does the effect of chronic pain and oxidative stress.

Other adverse effects have been found with Lyrica and Neurontin. A recent review study released found that several of the antiepileptic drugs, like Lyrica and Neurontin were associated with increased risk of infection. Another report showed severe muscle cell death and extreme bruising when Lyrica was combined with the antibiotic azithromycin in an elderly woman. The woman was being treated with Lyrica for chronic back pain for three months and had a single dose of the antibiotic for bronchitis. The combination caused a severe life-threatening illness.

Neurontin Adverse Effects
Neurontin also has been linked with vision abnormalities, suicide, sleep apnea, decreased breathing/hypoventilation, respiratory failure, muscle weakness/damage, and worsening of some autoimmune neurological disorders. It is also toxic to mitochondria, the energy-producing life force of our cells. It can adversely raise LDL cholesterol levels, cause sleep apnea, and has led to urinary-incontinence in adults. Once the drug was discontinued, the adverse effects were reversible.

If you need be on Lyrica, Neurontin or other similar drugs for severe problems, work with your provider to use it for the shortest time and lowest dose possible. Medical journals recommend very close drug therapy monitoring when using Lyrica or Neurontin.
**************************************************************************

Again, there's much more at the link:

http://www.wellnessresources.com/he...nd_lyrica_adverse_effects_the_saga_continues/


 

Alton

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Modern Medicine is a Disease

Doctors, their medical organizations and the great pharmaceutical companies practice a sinister form of medicine that directly causes suffering and pain in people's lives. Thus, I am not surprised when James Howard Kunstler writes that modern medicine is a hostage racket: "Medicine is now a catastrophe every bit as pernicious as the illnesses it is supposed to treat, and a grave threat to a nation that we're supposed to care about. If you thought banking in our time was a miserable racket — which it is, of course, and by "racket" I mean a criminal enterprise — then so-called health care has it beat by a country mile, with an added layer of sadism and cruelty built into its operations. Nobody in the system will say what anything costs and nobody wants to because it would break the spell that they work in an honest, legit business. The services are provided when the customer is under the utmost duress, often life threatening, and the outcome even in a successful recovery from illness is financial ruin that leaves a lot of people better off dead. The system is one of engineered criminality. It is inflicting ruin on millions." The majority of people believe in the medical pharmaceutical con - that the snake-oil remedies with all the side effects will actually cure their ailments. Many people believe this fantasy and are willing to bankrupt themselves and their families in their desperate and misguided need to believe. What they are buying into is disease because modern medicine is a disease, it is a plague and people die right and left from it.

Even when there is good news, when a cancer patient recovers after being poisoned with chemotherapy and radiation the bad news usually comes later when the cancer comes back or a number of side effects like heart attacks set in.

Con Men Who Believe

The religion of medicine is slowly being broken as we discover how fantastic their fantasies are. When we find out that judges at the German Federal Supreme Court (BGH) confirmed that the measles virus does not exist what are we supposed to think about the field of pediatrics and the integrity of companies that make vaccines. There is not a single scientific study in the world which could prove the existence of the virus in any scientific literature. This raises the question of what was actually injected into millions over the past few decades. Certainly nothing good.

We have doctors who like to inject heavy metals into newborn babies and they are called pediatricians. The Chinese are finding the nerve to finger vaccines as a major cause of Autism, a disease that most often offers a lifetime of torture for families.

In the first court award in a vaccine-autism claim the family of Hannah Poling received more than $1.5 million for her care, lost earnings, and pain and suffering for the first year alone. In addition to the first year, the family will receive more than $500,000 per year to pay for Hannah's care. In 2002, Hannah's parents filed an autism claim in federal vaccine court. Five years later, the government settled the case before trial and had it sealed.

Lawyers representing the Cherokee Nation filed a lawsuit against major pharmaceutical companies, claiming they have pumped dangerous painkillers into Native American communities in Oklahoma.

There is no end to medical madness and all the ways it can come back to haunt you. Cases of hepatitis C in the United States have nearly tripled within a five-year period, reaching a new 15-year high of around 34,000 new hepatitis C infections in 2015, federal health officials reported. Experts attribute the higher rates to more injection drug use during the ongoing opioid epidemic.

The Americans at the CDC and FDA would rather cover it all up and let the massacre of minds and hearts continue. The FDAhas actually "certified" a 2009 letter sent anonymously by FDA staff to President Obama describing "systemic corruption and wrongdoing that permeates all levels of FDA."

A 2017 study in Africa compared a DTP/OPV (diphtheria, pertussis, tetanus, oral polio) vaccinated group of children to an unvaccinated group. The authors found there was a 10-fold increase risk in death in the vaccinated group that received only the DPT shot, as compared to the unvaccinated group.

Merck's Gardasil vaccine causes death, collapse and chronic illnessin young women and girls, including a new, never-before described"disease" called Juvenile ALS, a fatal condition in which the nervoussystem is slowly destroyed while consciousness remains unimpaired.

In the flu vaccine, there is a whopping 51,000 ppb (parts per billion) of mercury in the multi-dose flu vaccine—the most common type of flu vaccine given. How much is 51,000 ppb? It is 25,000 times the legal maximum for mercury in drinking waterestablished by the Environmental Protection Agency. Keep in mind that when you inject mercury, it is 100% absorbed so it is more toxic to inject it as compared to eating it in fish or drinking it in water. Do pediatricians rise up against the CDC and complain?

For those who think vaccines are safe and pediatricians are saints in white jackets, know that the United States government, as of August 6, 2008, paid out 1.8 billion dollars ($1,804,415,262.35) to parents who brought the cases of their children killed by vaccines or severely damaged (autism) in front of the National Vaccine Injury Compensation Program.

Corporations that produce drugs that kill and hurt hundreds of thousands of people a year, even when they are properly prescribed, are protected by governments, politicians and arrogant medical officials.

Obamacare and the entire medical establishment paradigm is to force western medicine down everyone's throat. Karl Denninger says about Obamacare, "But for virtually everyone else these "plans" are nothing more than financial rape." "Every step of the way, the US medical system is greased to perpetuate fraud against taxpayers, against patients, against insurers," writes Mike Shedlock.

Conclusion

Contemporary medicine has become the practice of pharmaceutical terrorism. Too many doctors think they know better about how other peoples' lives should be lived or ended. "The FDA has assumed for itself Godlike power, requiring that its official approval be obtained before any substance can legally be used in the prevention and treatment of disease. The FDA's legal-regulatory control therefore is totalitarian and Napoleonic in construct; what it does not explicitly permit as a medicine is implicitly forbidden," writes Sayer Ji, founder of GreenMedInfo.com.

The worst terrorists are of course those who will not admit they are. Medicine kills more people than any other form of terrorism. Did you know that the CDC is looking for police powers for a mandatory vaccination program? Get vaccinated or go to jail!

Radiologists administer near lethal dosages meaning they put their cancer patients in front of a nuclear firing squad when they administer radiation as a cancer treatment.

When radiation therapy is used to treat cancer, a very large dose of radiation, about 5,000,000 millirem (or 5,000 rem) (50,000 mSv) is delivered to the tumor site. Below is a chart that says that each dose of radiation treatment delivers 2,000,000 millirem so with the multiple treatments most patients receive it is easy to see how fast they get up to a fatal dose. Ten thousand mSv is a fatal dose. That is 10,000,000 millirem.

The general nature of 'evil' is to not have consciousness of the effect that our actions have on the feelings and emotional world of others. Doctors have no excuse for how many people they kill each year, at least in America—statistics are kept and published.

The destiny of medicine is in the hands of madmen—totally deranged executives of big pharmaceutical companies in cooperation with the FDA and doctors—who are hell bent on getting as many people on their dangerous drugs as they possibly can.

Pharmaceutical terrorism is a term I coined 14 years ago when I published Cry of the Heart, a book about the tragic situation centering on the childhood vaccination program. That work reached its full expression in The Terror of Pediatric Medicine.

Dr. Viera Scheibner gives us an explanation of why some doctors have fallen to such a low state. "The inability to listen and observe the truth has created a breed of medical practitioners who inflict illness rather than healing, who become accusers rather than helpers, and who are ultimately just covering up - whether consciously or unknowingly, but with frighteningly increasing frequency - for the disasters created by their useless and deadly concoctions and sanctimonious ministrations." As long as Big Pharma runs medicine, we will never have a health care system that has interest in teaching people how to be healthy. When profits come from sickness, the corporations find creative ways of sickening people with their dangerous drugs, surgeries, chemotherapy and radiation treatments not to mention all their dangerous tests (CAT Scans) where they cannot even control the dosages of radiation most patients receive
 

Alton

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Oh boy! Hard EVIDENCE that the brains of men and women ARE different! (remember, it took a near genius with grant and gov money to figure this out...)

Linky: How men's and women's brains are different | Stanford Medicine


Two minds
The cognitive differences between men and women
By Bruce Goldman
Illustration by Gérard DuBois
When Nirao Shah decided in 1998 to study sex-based differences in the brain using up-to-the-minute molecular tools, he didn’t have a ton of competition. But he did have a good reason.



layers

“I wanted to find and explore neural circuits that regulate specific behaviors,” says Shah, then a newly minted Caltech PhD who was beginning a postdoctoral fellowship at Columbia. So, he zeroed in on sex-associated behavioral differences in mating, parenting and aggression.

“These behaviors are essential for survival and propagation,” says Shah, MD, PhD, now a Stanford professor of psychiatry and behavioral sciences and of neurobiology. “They’re innate rather than learned — at least in animals — so the circuitry involved ought to be developmentally hard-wired into the brain. These circuits should differ depending on which sex you’re looking at.”

His plan was to learn what he could about the activity of genes tied to behaviors that differ between the sexes, then use that knowledge to help identify the neuronal circuits — clusters of nerve cells in close communication with one another — underlying those behaviors.

At the time, this was not a universally popular idea. The neuroscience community had largely considered any observed sex-associated differences in cognition and behavior in humans to be due to the effects of cultural influences. Animal researchers, for their part, seldom even bothered to use female rodents in their experiments, figuring that the cyclical variations in their reproductive hormones would introduce confounding variability into the search for fundamental neurological insights.

But over the past 15 years or so, there’s been a sea change as new technologies have generated a growing pile of evidence that there are inherent differences in how men’s and women’s brains are wired and how they work.

Not how well they work, mind you. Our differences don’t mean one sex or the other is better or smarter or more deserving. Some researchers have grappled with charges of “neurosexism”: falling prey to stereotypes or being too quick to interpret human sex differences as biological rather than cultural. They counter, however, that data from animal research, cross-cultural surveys, natural experiments and brain-imaging studies demonstrate real, if not always earthshaking, brain differences, and that these differences may contribute to differences in behavior and cognition.

Nirao Shah studies how some genes at work in the mouse brain determine sex-specific behaviors, like the female trait of protecting the nest from intruders. He says most of these genes have human analogues but their function is not fully understood.
Nirao Shah studies how some genes at work in the mouse brain determine sex-specific behaviors, like the female trait of protecting the nest from intruders. He says most of these genes have human analogues but their function is not fully understood.
Photograph by Lenny Gonzalez

Behavior differences
In 1991, just a few years before Shah launched his sex-differences research, Diane Halpern, PhD, past president of the American Psychological Association, began writing the first edition of her acclaimed academic text, Sex Differences in Cognitive Abilities. She found that the animal-research literature had been steadily accreting reports of sex-associated neuroanatomical and behavioral differences, but those studies were mainly gathering dust in university libraries. Social psychologists and sociologists pooh-poohed the notion of any fundamental cognitive differences between male and female humans, notes Halpern, a professor emerita of psychology at Claremont McKenna College.

In her preface to the first edition, Halpern wrote: “At the time, it seemed clear to me that any between-sex differences in thinking abilities were due to socialization practices, artifacts and mistakes in the research, and bias and prejudice. ... After reviewing a pile of journal articles that stood several feet high and numerous books and book chapters that dwarfed the stack of journal articles … I changed my mind.”

Why? There was too much data pointing to the biological basis of sex-based cognitive differences to ignore, Halpern says. For one thing, the animal-research findings resonated with sex-based differences ascribed to people. These findings continue to accrue. In a study of 34 rhesus monkeys, for example, males strongly preferred toys with wheels over plush toys, whereas females found plush toys likable. It would be tough to argue that the monkeys’ parents bought them sex-typed toys or that simian society encourages its male offspring to play more with trucks. A much more recent study established that boys and girls 9 to 17 months old — an age when children show few if any signs of recognizing either their own or other children’s sex — nonetheless show marked differences in their preference for stereotypically male versus stereotypically female toys.

Halpern and others have cataloged plenty of human behavioral differences. “These findings have all been replicated,” she says. Women excel in several measures of verbal ability — pretty much all of them, except for verbal analogies. Women’s reading comprehension and writing ability consistently exceed that of men, on average. They outperform men in tests of fine-motor coordination and perceptual speed. They’re more adept at retrieving information from long-term memory.

Men, on average, can more easily juggle items in working memory. They have superior visuospatial skills: They’re better at visualizing what happens when a complicated two- or three-dimensional shape is rotated in space, at correctly determining angles from the horizontal, at tracking moving objects and at aiming projectiles.

Navigation studies in both humans and rats show that females of both species tend to rely on landmarks, while males more typically rely on “dead reckoning”: calculating one’s position by estimating the direction and distance traveled rather than using landmarks.

New technologies have generated a growing pile of evidence that there are inherent differences in how men’s and women’s brains are wired and how they work.
Many of these cognitive differences appear quite early in life. “You see sex differences in spatial-visualization ability in 2- and 3-month-old infants,” Halpern says. Infant girls respond more readily to faces and begin talking earlier. Boys react earlier in infancy to experimentally induced perceptual discrepancies in their visual environment. In adulthood, women remain more oriented to faces, men to things.

All these measured differences are averages derived from pooling widely varying individual results. While statistically significant, the differences tend not to be gigantic. They are most noticeable at the extremes of a bell curve, rather than in the middle, where most people cluster. Some argue that we may safely ignore them.

But the long list of behavioral tendencies in which male-female ratios are unbalanced extends to cognitive and neuropsychiatric disorders. Women are twice as likely as men to experience clinical depression in their lifetimes; likewise for post-traumatic stress disorder. Men are twice as likely to become alcoholic or drug-dependent, and 40 percent more likely to develop schizophrenia. Boys’ dyslexia rate is perhaps 10 times that of girls, and they’re four or five times as likely to get a diagnosis of autism spectrum disorder.

Could underlying biological differences — subtle though they may be for most of us — help explain these gaping
between-sex imbalances in the prevalence of mental disorders and account for the cognitive and behavioral differences observed between men and women?

How our brains differ
The neuroscience literature shows that the human brain is a sex-typed organ with distinct anatomical differences in neural structures and accompanying physiological differences in function, says UC-Irvine professor of neurobiology and behavior Larry Cahill, PhD. Cahill edited the 70-article January/February 2017 issue of the Journal of Neuroscience Research — the first-ever issue of any neuroscience journal devoted entirely to the influence of sex differences on nervous-system function.

Brain-imaging studies indicate that these differences extend well beyond the strictly reproductive domain, Cahill says. Adjusted for total brain size (men’s are bigger), a woman’s hippocampus, critical to learning and memorization, is larger than a man’s and works differently. Conversely, a man’s amygdala, associated with the experiencing of emotions and the recollection of such experiences, is bigger than a woman’s. It, too, works differently, as Cahill’s research has demonstrated.

In 2000, Cahill scanned the brains of men and women viewing either highly aversive films or emotionally neutral ones. The aversive films were expected to trip off strong negative emotions and concomitant imprinting in the amygdala, an almond-shaped structure found in each brain hemisphere. Activity in the amygdala during the viewing experience, as expected, predicted subjects’ later ability to recall the viewed clips. But in women, this relationship was observed only in the left amygdala. In men, it was only in the right amygdala. Cahill and others have since confirmed these results.

Discoveries like this one should ring researchers’ alarm buzzers. Women, it’s known, retain stronger, more vivid memories of emotional events than men do. They recall emotional memories more quickly, and the ones they recall are richer and more intense. If, as is likely, the amygdala figures into depression or anxiety, any failure to separately analyze men’s and women’s brains to understand their different susceptibilities to either syndrome would be as self-defeating as not knowing left from right.

The two hemispheres of a woman’s brain talk to each other more than a man’s do. In a 2014 study, University of Pennsylvania researchers imaged the brains of 428 male and 521 female youths — an uncharacteristically huge sample — and found that the females’ brains consistently showed more strongly coordinated activity between hemispheres, while the males’ brain activity was more tightly coordinated within local brain regions. This finding, a confirmation of results in smaller studies published earlier, tracks closely with others’ observations that the corpus callosum-— the white-matter cable that crosses and connects the hemispheres — is bigger in women than in men and that women’s brains tend to be more bilaterally symmetrical than men’s.

Many of these cognitive differences appear quite early in life. ‘You see sex differences in spatial-visualization ability in 2- and 3-month-old infants.’
“To some appreciable degree, these brain differences have to translate to behavioral differences,” says Cahill. Numerous studies show that they do, sometimes with medically meaningful implications.

A 2017 study in JAMA Psychiatry imaged the brains of 98 individuals ages 8 to 22 with autism spectrum disorder and 98 control subjects. Both groups contained roughly equal numbers of male and female subjects. The study confirmed earlier research showing that the pattern of variation in the thickness of the brain’s cortex differed between males and females. But the great majority of female subjects with ASD, the researchers found, had cortical-thickness variation profiles similar to those of typical non-ASD males.

In other words, having a typical male brain structure, whether you’re a boy or a girl, is a substantial risk factor for ASD. By definition, more boys’ than girls’ brains have this profile, possibly helping explain ASD’s four- to fivefold preponderance among boys compared with girls.

Why our brains differ
But why are men’s and women’s brains different? One big reason is that, for much of their lifetimes, women and men have different fuel additives running through their tanks: the sex-steroid hormones. In female mammals, the primary additives are a few members of the set of molecules called estrogens, along with another molecule called progesterone; and in males, testosterone and a few look-alikes collectively deemed androgens. Importantly, males developing normally in utero get hit with a big mid-gestation surge of testosterone, permanently shaping not only their body parts and proportions but also their brains. (Genetic defects disrupting testosterone’s influence on a developing male human’s cells induce a shift to a feminine body plan, our “default” condition.)

In general, brain regions that differ in size between men and women (such as the amygdala and the hippocampus) tend to contain especially high concentrations of receptors for sex hormones.

Another key variable in the composition of men versus women stems from the sex chromosomes, which form one of the 23 pairs of human chromosomes in each cell. Generally, females have two X chromosomes in their pair, while males have one X and one Y chromosome. A gene on the Y chromosome is responsible for the cascade of developmental events that cause bodies and brains to take on male characteristics. Some other genes on the Y chromosome may be involved in brain physiology and cognition.

Scientists routinely acknowledge that the presence or absence of a single DNA base pair can make a medically important difference. What about an entire chromosome? While the genes hosted on the X chromosome and the Y chromosome (about 1,500 on the X, 27 on the Y) may once have had counterparts on the other, that’s now the case for only a few of them. Every cell in a man’s body (including his brain) has a slightly different set of functioning sex-chromosome genes from those operating in a woman’s.

Sex-based differences in brain structure and physiology reflect the alchemy of these hormone/receptor interactions, their effects within the cells, and the intermediating influence of genetic variables — particularly the possession of an XX versus an XY genotype, says Cahill.

Zeroing in on neural circuits
Shah’s experiments in animals employ technologies enabling scientists to boost or suppress the activity of individual nerve cells — or even of single genes within those nerve cells — in a conscious, active animal’s brain. These experiments have pinpointed genes whose activity levels differ strongly at specific sites in male versus female mice’s brains.

What would happen, Shah’s team wondered, if you knocked out of commission one or another of these genes whose activity level differed between male and female brains? They tried it with one of their candidate genes, turning off one that was normally more active in females.

Doing this, they found, totally shredded mouse moms’ willingness to defend their nests from intruders and to retrieve pups who had wandered away — maternal mandates that normal female mice unfailingly observe — yet had no observable effect on their sexual behavior. Torpedoing a different gene radically reduced a female mouse’s mating mood, but males in which the gene has been trashed appear completely normal.

All this points to a picture of at least parts of the brain as consisting of modules. Each module consists of a neural or genetic pathway in charge of one piece of a complicated behavior, and responds to genetic and hormonal signals. These modules — or at least some of them — are masculinized or feminized, respectively, by the early testosterone rush or its absence. The mammalian brain features myriad modules of this sort, giving rise to complex combinations of behavioral traits.

Which is not to say every man’s or woman’s brain looks the same. Our multitudinous genetic variations interact with some of our genes’ differential responsiveness to estrogens versus androgens. This complicated pinball game affects goings-on in at least some of the brain’s neural circuits and in whatever little piece of behavior each of these neural circuits manages.

“We think gender-specific behavior is a composite of all these modules, which, added up, give you your overall degree of maleness and femaleness,” says Shah.

Consider the genes Shah has isolated whose activity levels differ significantly in the brains of male and female mice. “Almost all of these genes have human analogues,” he says. “We still don’t completely understand their function in human social behavior. But when we looked at publicly available databases to find out what we do know about them, we found a surprising number that in humans have been linked with autism, alcoholism and other conditions.”

Bigger imaging studies and imaginative animal research now in the works promise to reveal much more about humanity’s inherent — although by no means uniform, and often not substantial — sex-associated cognitive differences and vulnerability to diseases.

Trying to assign exact percentages to the relative contributions of “culture” versus “biology” to the behavior of free-living human individuals in a complex social environment is tough at best. Halpern offers a succinct assessment: “The role of culture is not zero. The role of biology is not zero.”
 

Alton

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#11
Of special interest to those with back pain:

Linky: Investigative Journalist Exposes the Fraudulent Back Pain Industry - Waking Times

Investigative Journalist Exposes the Fraudulent Back Pain Industry
June 3, 2017


Anna Hunt, Staff
Waking Times

A recently published book by investigative journalist Cathryn Jakobson Ramin reveals that the back pain industry may be more crooked than you think. In her book, Crooked: Outwitting the Back Pain Industry and Getting on the Road to Recovery, Ramin exposes the motive behind frightening diagnoses and the influence of pharmaceutical companies. In addition, she shatters assumptions about surgery, chiropractic methods and spinal injections.

It is estimated that about 62 million American adults suffer from some type of back pain. The back pain industry is worth about $100 billion dollars per year. Nevertheless, most treatments and therapies are ineffective and sometimes even dangerous.



The Secrets of the Back Pain Industry
Ramin spent six years traveling around the world talking with patients, health-care professionals, and therapists. She conducted over 600 interviews. In addition, she had spent many years and thousands of dollars treating her chronic back pain. In the end, Ramin found that a big problem exists when it comes to spine medicine.

Next Avenue interviewed Ramin about her research. Here are some of the most important highlights from the book.

Many Treatments are Either Unnecessary or Dangerous
In her research, Ramin interviewed countless health care professionals to uncover which treatments are actually effective. Here’s her opinion about chiropractic care:

If you just developed back pain, there’s evidence that one to two sessions with a chiropractor may help you. More than that, there’s absolutely no evidence for it, and anyone who has gone to see a chiropractor knows there are very few chiropractors who want to see you for one to two sessions. The moment you come through that door, you are told that, for maintenance purposes, you need to come very, very regularly for a very, very long time, maybe forever. And there is no evidence at all for that.

When she polled 100 spine surgeons, here’s what she discovered:

This was a question posed to spine surgeons: ‘Would you have spine surgery?’ [Specifically lumbar fusion or disc replacement surgery.] And resoundingly, in this group, all said ‘No,’ except one. Now, that should tell you all you need to know.

The Opioid Epidemic Connection
The typical response by a doctor when treating someone with back pain is to offer pain relief. And the simplest way to do this is with pharmaceuticals. Ramin states:

What happened was doctors felt compelled to prescribe opioids to patients who were suffering. And the drug companies were right behind that, pushing that all back pain should be treated immediately with opioids.



There is little contention to the claim that prescription painkillers are dangerous. They have been responsible for over 183,000 deaths over the last 15 years. Some particular brands have killed thousands. Furthermore, misuse, abuse and addiction are rampant. For example, in 2014, almost 2 million Americans abused or were dependent on prescription opioids.

Interestingly, a recent study out of the University of Colorado-Boulder has found that prescription opioids may actually worsen chronic pain. Furthermore, the study discovered that these drugs may in fact prolong the condition that they are supposed to help placate.

You Are Probably the Only One Who Can Fix You
In her book, Ramin stresses that many doctors and therapists in the back pain industry will lead you to therapeutic dead ends. She states:

Before you decide to put your faith in any provider, look extremely closely at that provider’s record. If you get sent for an MRI a couple of days after back pain with no intention of having surgery, ask why you are going for that MRI, because the only use for an MRI is for preparation for either surgery or an epidural steroid injection.

Consequently, what helped Ramin defeat her chronic back pain was “intensive, directed exercise.” She discovered that therapists dole out lots of disinformation, which makes it difficult for sufferers to find out what works. But, according to Ramin, it will be up to you to fix your back pain, and no one else.

The bad news here, or maybe it’s good news, is that you are not going to find someone who will fix you. You will be the fixer. You will be the one who develops the intensive exercise program that is going to allow you to escape from this.

About the Author
Anna Hunt is the founder of Awareness Junkie, a community paving the way to better health, a balanced life, and personal transformation. In addition, she is the proprietor of OffgridOutpost.com, an online store offering GMO-free healthy storable food and emergency kits. Anna is a certified Hatha yoga instructor and founder of Atenas Yoga Center. She enjoys raising her children and being a voice for optimal human health and wellness. Visit her essential oils store here.

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This article (Investigative Journalist Exposes the Fraudulent Back Pain Industry) was originally created and published by Waking Times and is published here under a Creative Commons license with attribution to Anna Hunt and WakingTimes.com. It may be re-posted freely with proper attribution, author bio, and this copyright statement.

My comments;

My first bout with stenosis back in the mid to late 80's made me face a decision which I still do not regret to this day and that was to have back surgery or not. I decided no surgery. Did the physical therapy thing and moved on once I could move regularly with little pain. Yeah, it wasn't especially easy but nowhere near as hard as one would think. So here I am again... pain pills, steroid injections and I have to deliver the decision to my doctor on the 22nd of this month. I'm thinking once again I will be saying no to surgery despite my worsened condition. I also think that once again physical therapy will be the answer. Only this time I will need to add different exercises to include more of a focus on my abdominal muscles to provide adequate support for my back and probably some extra exercises for my back muscles. I'll have to add these to my daily 3 S's beauty routine :)
 

Alton

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How Stupid Can Scientists Be? No limit has yet been discovered or imposed. Scientists claim they do it because:
1) They can.
2) They MUST because science cannot be hampered by baseless things such as moral or ethical concerns
3) So they can figure out the mechanisms to stop whatever it is they researching

How To Kill a Whole Lot of People: Scripps Scientists Publish How They Made H7N9 Virus More Transmissible

By Janet Phelan

In 2014, a moratorium was placed on federally funded research which involved making flu viruses more lethal. The moratorium was placed after heated debate generated by research published by a Netherlands team, headed up by Ron Fouchier. Fouchier’s research had produced a strain of H5N1 which was able to go airborne, thus greatly enhancing its ability to spread. Fouchier focused on the transmission of the disease among ferrets, which are the lab stand-in for people.

Scientists Publish Recipe For Making Bird Flu More Contagious

Now, scientists in California have published research concerning enabling the human-to-human transmission of the bird flu virus H7N9. This virus strain is of concern to scientists as it has already infected 1500 people and killed 40% of them. (MY comment: That's 600 people +/-)[emphasis added] H7N9 has not been known, however, to spread easily from human contact.


The article explaining the three genetic changes which need to be made to transform H7N9 into a virtual pandemic agent was published on June 15, 2017 in the journal PLOS Pathogens.

Three mutations switch H7N9 influenza to human-type receptor specificity

According to Scripps biologist Jim Paulsen, as quoted in an NPR article, “As scientists we’re interested in how the virus works…. We’re trying to just understand the virus so that we can be prepared.”

A Few Genetic Tweaks To Chinese Bird Flu Virus Could Fuel A Human Pandemic

The NPR article quotes Paulsen as stating he wants next to test the mutated strain on ferrets.

Reuters reported on a number of scientists who were enthusiastic about the Scripps findings. Reuters quoted immunology expert Fiona Culley, who stated that “This study will help us to monitor the risk posed by bird flu in a more informed way, and increasing our knowledge of which changes in bird flu viruses could be potentially dangerous will be very useful in surveillance.”

Three mutations could make bird flu a potential pandemic: study

Reuters also quoted virologist Wendy Barclay. “These studies keep H7N9 virus high on the list of viruses we should be concerned about,” she said. “The more people infected, the higher the chance that the lethal combination of mutations could occur.”

Not all the scientists interviewed were happy about the research. When posed with the question of scientists making the genetic changes in the actual H7N9 virus, David Relman, a Stanford professor of microbiology and immunology, was quoted by NPR as stating, “I would be very hesitant, were they to want to do that. In fact, I would be reluctant to have them do that.”

What are the chances that this research may be used for nefarious purposes?

Since 2001, the US government has poured over $100 billion dollars into what was initially called “Biodefense” but has euphemistically been renamed “Health Security.” Many of these programs are dual-use; that is to say the research can be used for either protection or weaponization. Scientists argue that it is necessary to first create the weapon (in this case a pandemic agent) in order to research the cure.

However, the US’s record of straightforwardness surrounding her “Biodefense” or “Health Security” programs has been abysmal. The limp-wristed investigation into the anthrax mailings of 2001, in which federal investigators neglected or refused to consider any lab but Fort Detrick as the locus for mailing the anthrax spores — which killed five and sickened over a dozen — resulted in the probable culprit at US Army’s Dugway Proving Ground getting a “Get out of Jail Free” card.

It was less than two years ago when Dugway was caught sending live anthrax through the mail to labs, worldwide. Initially, it was thought that nine labs received the live anthrax. The number soon expanded and it was ultimately admitted that 575 separate shipments of live anthrax had gone out in the span of a decade.

CDC: DoD anthrax errors involved 575 shipments

The official excuse, “We didn’t know our deactivating equipment wasn’t working!” was suspect, given numerous earlier reports that the equipment was faulty.

It has also come to light that the US has been leading the UN around by its virtual nose and providing false information both to the Biological Weapons Convention and also to the 1540 Committee concerning its “Biodefense” programs.

The reality is that the sort of research that delves into how to make H7N9 spread easily and efficiently among humans is the kind of research that should raise substantial alarm. According to sources in the US government, the moratorium on publishing this type of research is soon to be lifted. Shortly, anyone with two specimen vials to rub together may very well be able to surf the Web and learn how to create a worldwide plague. And in our current technocracy, with its worship of science as an inherent good, there just doesn’t seem to be much concern about this.

In 1998, Secretary of State Madeleine Albright said,“Iraq is a long way from [America], but what happens there matters a great deal here. For the risk that the leaders of a rogue state will use nuclear, chemical or biological weapons against us or our allies is the greatest security threat we face. And it is a threat against which we must and will stand firm.”

We never found those weapons in Iraq. In our zeal to protect ourselves from bogeymen and “rogue states,” we may well have become the very threat that we feared.

MY comments:
How much of this will be weaponized by government? Spanish Flu GLOBAL epidemic ring a bell? When was that? Why, at the end of World War 1. Apparently Wilson made the world "safe for democracy" and any virus governments may want to use. Yes, that IS just opinion AND speculation on my part or is it? Only time will tell as secrets keep being revealed about the activities of the government.

We already know that any evil discovered or made in a lab WILL escape into the wild at some point whether by error or deliberation, the reasons never really matter anyway, we won't know until AFTER it happens. So, everybody ready for the most deadly flu imaginable...to satisfy a scientist's quest and desire "to know how this stuff works"?

addenda:

In case you think my tinfoil hat is on a little too tight you may want to check out what DARPA is doing to weaponize the environment:
Weaponized Plants: Pentagon's Synthetic Organisms Could "Militarize the Environment" · The Mind Unleashed
 
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Alton

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Lots of interesting and timely stuff this week!

First let's start with poison ivy. I'm one of those oddballs who has NEVER had poison ivy. I know I've been in it, cut it, broke it, rolled in it, crawled through it, etc., and never have had it. Mrs. Alton gets near and poof! Got the itch. My oldest son is pretty much the same way. My youngest is more like me. This is not to infer heredity or some sort of genetic cause, though I'm sure they're involved to some degree. But it pretty much comes down to just how well you clean the the oil, called ushiol (oo-she-all), from your skin. Turns out Dawn dish detergent and a vigorous wiping of the affected area with a washcloth will generally stop the oil from causing a rash. Here's the link and take the time to watch the video:

Best Home Remedies for Poison Ivy


Next is MORE "better living through chemistry" approved for you without a word in any media by your friends at the EPA (NO connection to FDA...) here:
The GMO Agenda Takes a Menacing Leap Forward with EPA’s Silent

Last, but by no means least is from a Russian doctor, a Doctor Natasha with a hyphenated last name. She still has a heavy accent so you will probably need to listen closely to the video. Anyway, some new-to-some info as an overview of the relationship between your gut flora (all the different types of bacteria, both good and bad, living in your bowels) and various physical ailments and low levels of various compounds in your body made ONLY or originating only from the gut flora. This will be of particular interest to those dealing with arthritis (inflammation), Irritable Bowel Syndrome (IBS) and other stuff mentioned in the video.
Article and video: Neurologist and Gut Specialist Claims to Possess Cure Mainstream Doctors Don't Want You to Know About | Alternet

Video only:



Doctor Natasha's website: Dr Natasha - GAPS (Gut and Psychology Syndrome)
 

90%RealMoney

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I get a rash just being in the proximity of poison oak, which is all over my place. Had to do the steroid pack thing three times I believe. Do NOT, EVER, burn poison oak, Ivy, or Sumac. You can breathe in the oils, vapors, and you're going to have real problems.
 

Alton

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This simply cannot be overstated - GET YOUR VITAMIN D!

Nope! Not hair-brained new age bio-babble. Not the words or thoughts of overwrought health fanatics. This IS for YOUR health and well-being.

The FACTS keep piling up and are continually proven again and again...Your body NEEDS vitamin D. The US Recommended Daily Allowance is woefully low and does not even begin to approach what the body REQUIRES as a daily healthy level. Here's the link:Vitamin D3 Versus D2 Here's the latest facts, info and sources:


It's something I've been encouraging for several years now — making sure you're getting adequate levels of vitamin D, not only because it's a crucial nutrient, but because so many people are deficient and don't realize it. But a new study has emerged dispelling the idea many scientists and health care providers have had for many years, the upshot being that there is a vast difference between vitamin D2, which is plant-based (notably from mushrooms), and vitamin D3, which is derived from animal products.

The two do not, as some have believed, have a similar nutritional value. Health authorities are calling for official recommendations for vitamin D intake to be changed in accordance with the "new" information, which is not actually new, as we've related this important distinction for some time. The "groundbreaking" study from the University of Surrey was conducted to determine, between vitamins D2 and D3, which was more effective in raising levels in the body.

The trial was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) — "the largest U.K. public funder of nonmedical bioscience" — and the Diet and Health Research Industry Club (DRINC). Susan Lanham-New, principal investigator of the trial, called the results a "very exciting discovery which will revolutionize how the health and retail sector views vitamin D," EurekAlert! reported.1

She added, "Vitamin D deficiency is a serious matter, but this will help people make a more informed choice about what they can eat or drink to raise their levels through their diet." Serious is right: one study shows that more than 40 percent of the American population is deficient in vitamin D,2 and some experts say the problem is serious enough to call it a pandemic.3

Vitamin D2 and D3: Not Interchangeable

Vitamin D is produced by your body after exposure to the sun, and because winter is the period during which sunshine is least available, vitamin D levels are typically at their lowest during this time.

The 335 South Asian and white European women who participated in the study over two winters were divided into five groups and given either juice containing vitamin D2 or D3, a biscuit with the same or a placebo. At the conclusion of the study, researchers found vitamin D3 to be twice as effective in raising levels in the body in comparison to D2. EurekAlert reported: "Vitamin D levels in women who received vitamin D3 via juice or a biscuit increased by 75 percent and 74 percent respectively compared to those who were given D2 through the same methods. Those given D2 saw an increase of 33 percent and 34 percent over the course of the 12-week intervention. The research also found that nutrient levels of both vitamin D2 and D3 rose as a result of both food and acidic beverages such as juice, which were found to be equally as effective. Those who received the placebo experienced a 25 percent reduction in the vitamin over the same period."4 What's interesting, as mentioned, is that the information from this latest study is not new news. A similar study back in 2011 is one of several instances where vitamin D3 has been shown to have a much greater significance for your health compared to D2. One study 5 shows D3 to:

- Convert to its active form 500 percent faster

- Be 87 percent better at raising and maintaining vitamin D levels

- Produce two to three times greater storage of the vitamin than D2

Recommendations for Vitamin D Outdated and Unsafe

Here's where it gets problematic: Several governments around the world, including the U.S. National Institutes of Health, assert there's no difference between vitamins D2 and D3 and that interchanging the two makes no difference whatsoever in your body's levels. However, the latest information from Public Health England reveals that more than 1 in 5 people in the U.K. have low levels of vitamin D, so the intake they now recommend is 10 micrograms per day, all year long, for everyone beginning at age 4.

EurekAlert! notes that daily intake of vitamin D3 — but not vitamin D2 — will allow the population to avoid such health problems as rickets, osteoporosis and a higher risk of developing heart disease, all associated with individuals with insufficient levels of vitamin D in their bodies.

What the scientists found influences public health but also retail markets in that many have added vitamin D2 to their products because they were led to believe it was just as viable in the body to increase people's "D" levels as taking D3. Lead study author and dietitian Laura Tripkovic explained: "The importance of vitamin D in our bodies is not to be underestimated, but living in the U.K. it is very difficult to get sufficient levels of it from its natural source, the sun, so we know it has to be supplemented through our diet. However, our findings show that vitamin D3 is twice as effective as D2 in raising vitamin D levels in the body, which turns current thinking about the two types of vitamin D on its head."6 Tripkovic explained that people who eat vitamin D3-rich foods or take supplements are two times more likely to raise their vitamin D profile than when consuming the equivalent in vitamin D2 foods such as mushrooms, D2-fortified bread or taking D2 supplements.

Downsides of Low Vitamin D Versus Benefits of Optimal Levels

Vitamin D is involved in the biology of all cells in your body, including your immune cells. A large number of studies have shown raising your vitamin D level can significantly reduce your risk of cancer and many other chronic diseases.So what happens when someone isn't getting the amount of vitamin D that they should? Daily Mail7 notes that lack of vitamin D:

- Can cause your bones to become thin, brittle or misshapen

- Is linked to an increased risk of multiple sclerosis

- Is linked to a growing prevalence for children to develop rickets, shown in many cases to cause malformed and/or broken bones

- Appears to play a role in insulin resistance, high blood pressure and immune function, related to heart disease and cancer

People who are obese, older than age 65 and/or housebound may have lower levels of vitamin D due to their diets, little sun exposure and other factors, and among dark-skinned individuals in the U.S, only 3 percent among thousands have enough vitamin D, which is a 9 percent drop from 20 years ago.8 Beyond cancer prevention, a Swiss study9 from 2013 lists several of the more dramatic benefits of getting the right amount of vitamin D:

- The development, function and maintenance of healthy bones and regulation of calcium homeostasis throughout life

- The basis for the prevention and management of osteoporosis, a disease producing brittle bones that are prone to fractures

- The regulation of neuromuscular function, reducing the risk of falls, a major cause of bone fractures

- Possibly a central component of musculoskeletal health through vitamin D's beneficial effects on muscle function and bone stability

- May show favorable effects in many organs and play a significant role in the maintenance of general health

Vitamin D and Omega-3 Fatty Acids: Two Crucial Nutrients for Health

According to Pharmacy Times, studies indicate that around 50 percent of adults worldwide have a vitamin D deficiency. Interestingly, in reviewing "potential mechanisms by which vitamin D might influence development of cardiovascular disease (CVD)" — and there's evidence that there is a link — there's also a possibility that CVD may cause low vitamin D levels rather than the other way around.10

In 2018, the VITamin D and OmegA-3 TriAL (VITAL) will conclude the first part of its review to provide evidence to indicate whether 2,000 IUs per day of vitamin D supplementation, with or without omega-3 fatty acids, has any specific CVD effects. Specifically: "The large study has enrolled about 25,000 healthy, middle-aged American adults. It has also been structured to gauge long-term effects. VITAL is expected to augment the wealth of information that we possess concerning vitamin D supplementation for bone health."11

You may already be aware that vitamin D and omega-3 fatty acids are two of the most important nutrients your body needs, but most people have no idea if they're deficient in either of them. A test kit is available, however, to quickly and safely analyze your blood levels while at the same time helping to augment consumer-sponsored scientific research.

The testing is performed by an independent research organization comparing these nutrients, and reveals your own vitamin D and omega-3 index (a measure of the omega-3s in your red blood cells) to let you know whether corrective action is needed. For more information about the nonprofit GrassRoots Health initiative and to learn how to get your own test kit, click here.

The Significance of Getting Adequate Sunlight

Another reason vitamin D levels are so important is that hepatic mitochondria and their associated microsomal enzymes metabolize vitamin D, whatever the source, Pharmacy Times noted, adding: "When patients consume too much vitamin D2 or vitamin D3, this process is completely unregulated and patients' vitamin D levels will rise proportionally to their intake. On the other hand, cutaneous synthesis from sun exposure allows patients levels to reach a preset point, and after that, additional sun exposure will not increase vitamin D levels."12 This means the best way to make sure you're getting enough vitamin D is to get regular sensible exposure to direct sunlight on your body each day. Depending on your locale, in the winter when the sun hides behind clouds and temperatures are often so chilly you're forced to wear long sleeves and galoshes, this may be difficult if not impossible, however.

Alternatively, adding vitamin D3 supplements to your regimen can help you achieve optimal vitamin D levels. The foods you eat can also make a difference in helping to make or break your health (if not your bones). The best foods for increasing your vitamin D intakevia your diet are animal-based and quite limited:

- Raw milk

- Eggs, particularly the yolk from organic, free-range eggs

- Wild-caught Alaskan salmon and other healthy fish such as mackerel and sardines, preferably from cold waters, and not farmed

Get Your Vitamin D Levels Tested

If you decide your vitamin D3 should be taken in supplement form, it's your serum level, or how much D3 your blood contains, that determines how much you should take until your levels are optimized to between 50 and 70 nanograms per milliliter, or ng/ml.

Studies done by Grassroots Health13 recommend about 8,000 IUs (the International Unit by which fat-soluble vitamins are measured) daily of vitamin D3 to raise your serum levels above 40 ng/ml. Children may need about 35 IUs per pound of body weight; however, getting your blood tested is the only way to know for sure whether your vitamin D levels are within the optimal range and, consequently, how much oral vitamin D3 you may need. Also be sure the vitamin D you take is correctly balanced with vitamin K-2.

An Atlanta-based Emory University School of Medicine study published in the Journal of the American College of Cardiology outlined vitamin D's association with cardiovascular disease prevention.

The upshot is that levels below 20 ng/ml are simply not enough to maintain bone health, let alone provide the other disease-prevention benefits that vitamin D has to offer. As mentioned, optimal levels of vitamin D are between 50 and 70 ng/ml. Medical News Today pinpointed why the latest study and subsequent calls for government entities to increase recommendations are so important: "Vitamin D deficiency appears to be widespread, and, as more research is conducted, it becomes increasingly clearer that this nutritional deficit is having a significant impact on the health of the country overall. Studies such as this may play a role in improving awareness, and, eventually, reversing the trend."14 Sources and references here.
 

Alton

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A GIANT Leap Forward?

Sorry gravity. The evidence has long been in, your body, your world, your universe IS electrical. Prior to Einstein's theories James Clerk Maxwell and many other renowned scientists of the period, before and since have demonstrated that the universe, earth and you and me all run on electricity. Now that we've passed through the Einstein segue, we're getting back on track to making genuine advances in science and health. Personally I find it extremely exciting that technologies are coming to market at last that purport to make use of this knowledge. Conversely I'm scared as hell of WHO is doing this...NOT your friends or mine, BIG Pharma! Their track record is less than stellar. Their products are less than effective. They have demonstrated repeatedly that they want absolutely NOTHING to do with cures, healing or the promotion of health as such things stand athwart of their business models. Having experienced and been victimized by their products and business model I cannot help but seeing a Trojan Horse here. The electrical doohickeys will have to be programmed and controlled/adjusted. This means CHIPS. This means EXTERNAL communication with such chips to effect control/adjust of the devices. Wha other information will be in these chips? These and many more questions are, at this point without answer to the public. Hopefully, my tinfoil hat is on too tight and I will be proven the fearful fool, of course, I don't really believe it will go that way. Anyway, here's the Wall Street article:

https://www.wallstreetdaily.com/2016/03/10/electroceuticals-glaxosmithkline-gsk/



One day, in the not too distant future, you might not recognize the pharmaceutical industry...


UK-based pharmaceutical giant GlaxoSmithKline has partnered with South San Francisco-based Verily to create Galvani Bioelectronics – a joint venture to develop implantable bioelectric medicines, a branch of medicine that works to fight diseases by targeting electrical signals in the body.
Right now, pharmaceutical firms develop drugs that interact biochemically with our bodies in order to treat various diseases and conditions. But that's changing...

A number of pharmaceutical companies will eventually transform into bioelectronics companies. Their treatments will consist of tiny implantable devices that "speak" the body's electric language.

Think of it as a type of technology similar to a heart pacemaker. But much, much more advanced.

The Brave New World of Electroceuticals

Welcome to the brave new world of neuromodulation and electroceuticals. It's a world where neural signal modulation will be the treatment path followed by tomorrow's doctors, not drugs.

Most electroceuticals will be about the size of a grain of rice. The devices will be attached to peripheral nerves and will modulate neural signals.

This will be a quantum leap from current disease treatment methods using drugs, which are actually very blunt instruments. And we all know about the numerous side-effects drugs can cause...

Whereas regulating the electrical firings of neural circuits can be far more precise and without the nasty side-effects. So says Kristoffer Famm, Vice President of Bioelectronics at GlaxoSmithKline Plc (GSK). As he told the Financial Times, "The nervous system is a fundamental control system in biology."

And the nervous system is where scientists are exploring new frontiers. Prime early opportunities bioelectronics research is focusing on metabolic, cardiovascular, and inflammatory disorders.

Bioelectronics Research

One prime area of research for bioelectronics is the brain and epilepsy. Epilepsy is directly caused by an electrical malfunction of the brain. This common neurological disease affects more than 50 million people worldwide. And conventional drugs aren't really that effective in combating it.

However, most current bioelectronics research is focused on the electrical language of peripheral nerves outside the brain and spinal cord. It's these nerves that influence the function of every organ in the body.

DARPA (the Defense Advanced Research Projects Agency) is involved in the field through its $79 million Electrical Prescriptions (ElectRx) initiative.
 

Alton

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How Body Voltage Dictates Health and Disease



Story at-a-glance

Your body runs on bioelectricity. Cells are designed to run in an environment of -20 to -25 millivolts. To repair and heal, cells need an environment of -50 millivolts
Inadequate voltage is a characteristic of all chronic disease. Either you do not have the necessary voltage to run the cells, or the higher voltage needed to make new cells
To heal, you need the proper voltage. You also need all of the necessary raw materials (nutrients) required to make new cells and address any toxins that might damage cells as fast as you make them


By Dr. Mercola

Your body runs on bioelectricity, and having a deeper understanding of how it works can be quite helpful when it comes to optimizing your health. Natural health pioneer Dr. Jerry Tennant has written an excellent book on this topic called "Healing Is Voltage: The Handbook."
The Electric Brain

Trained as an ophthalmologist, Tennant transitioned into natural health as a result of being forced to solve his own health challenges. After doing laser eye surgery on a patient with leukemia, Tennant ended up developing encephalitis. He believes the virus, which is not killed by laser, traveled from the patient's cornea, through the mask, up through his nose into his brain. He was forced to quit work in November 1995, and spent the next seven years bedridden, without hope for recovery.

"I went to the best doctors I could find in New York, Boston and so forth. They all said, 'Well, sorry. You have three viruses in your brain. We don't know what to do about it. Don't call us. We'll call you.' I had two or three hours a day in which I could understand the newspaper. Then like a light switch, it would go off and I couldn't understand it anymore. During those two or three hours that I could think, I realized I had to figure out how to get myself well, because no one else was going to do it.

I had the idea that if I could figure out how to make one cell work, I could make them all work, because although they look different, they really all have the same component parts. They just have different software. I began to read cellular biology books … One of the things that resonated with me was that … cells must run at a pH between 7.35 and 7.45. I didn't really know what that meant, except it was something about acid-base balance.

I began to try to understand pH. I began to realize that pH is the name given to voltage in a liquid. If you think about the voltage that runs electric lights or a computer, that's called conductive electricity. That means electrons are moving along copper wires. But in a liquid, you have a different situation. A liquid can either be an electron donor or an electron stealer.

By convention, if the liquid … is an electron stealer, you put a plus sign in front of the voltage. If it's an electron donor, you put a minus sign in front of it. You take a sophisticated volt meter called a pH meter and put it in the liquid. It will actually read out in voltage; minus 400 millivolts of electron donor is the same thing as pH of 14. Plus 400 millivolts of electron stealer is the same as a pH of zero. Of course, if it's neutral, it's a pH of 7."

Healing Requires Double the Voltage
Download Interview Transcript

A pH meter can give you a reading of either pH or millivolts. It's actually easier to understand what's going on if you use millivolts. A pH of 7.35 equates to -20 millivolts of electron donor. A pH of 7.45 is -25 millivolts of electron donor. Cells are designed to run in an environment of -20 to -25 millivolts.

People get confused because if you measure across a cell membrane you get about minus 90 millivolts. But the environment is designed to be -20 to -25 millivolts.

"That was a critical piece of my understanding to begin to understand how to get myself well," Tennant says (who, by the way, turned 77 this past June and still enjoys healthy mental faculties and goes to work every day). To repair and heal, on the other hand, cells need an environment of -50 millivolts. In other words, you need double the normal voltage to repair or replace damaged cells.

"Dr. Hiroki Nakatani in Japan was the first person to use modern electronics to measure acupuncture meridians. He published his work in 1951. Dr. Reinhard Voll in Germany did similar work and published it in 1952. I was able to get Nakatani's rather rudimentary device (an ohmmeter) and found that my brain was running somewhere between 2 and 4 millivolts, instead of the 25 that it needed to run and the 50 it needed to repair.

Now, it was obvious why it didn't work," he says. "Understanding that my brain didn't have enough voltage to work correctly, that was really what started me on the journey of trying to figure out how to get things to work again."

Chronic Disease Is the Result of Failure to Make Functional Cells

First, he came across work by a Russian doctor named Alexander Karasev, who had identified a waveform that can transfer electrons to cell membranes. He was able to acquire a SCENAR device developed by Karasev and began to treat himself with it. Years later, he developed his own Biomodulator device.1

"As I began to recognize that the body had to have energy, the other big change in my paradigm was when I finally understood that the body is constantly wearing itself out and having to make new cells. You get new cones in the macula of your eye every 48 hours. The lining of the gut is replaced every three days. The skin that you and I are sitting in today is only 6 weeks old. Your liver's 8 weeks old. Your nervous system's 8 months old.

One of the things I began to realize then is that chronic disease only occurs when you lose the ability to make new cells that work. [By extension], if you say that you must have a cell that works, that cell must contain functional mitochondria. But the mitochondria are not going to work if the cell membranes don't work.

It's the total unit that you have to have working. It's sort of like having a brand-new car. If it doesn't have a transmission, even though you've got the rest of it there, it's not going to work. You have to have the whole thing … Cells actually have four battery packs. The mitochondria are only one of those battery packs. You want them all to be functional."

In a nutshell, inadequate voltage is a characteristic of all chronic disease. Either you do not have the necessary voltage to run the cells, or the higher voltage needed to make new cells. So, to heal, you need the proper voltage. You also need all of the necessary raw materials (nutrients) required to make new cells and address any toxins that might damage cells as fast as you make them.
Body Electric — The Human Battery System

According to Tennant, there are four major battery systems in the human body that make cells work. The largest is your muscle battery. Your muscles are piezoelectric, which means that when you engage your muscles, electrons are emitted. In a way, your muscles act like rechargeable batteries, so while they emit electrons, they also store them.

To recharge the "battery pack" in your muscles, all you need to do is move and exercise. In summary, the four battery systems found in the human body are as follows. All of these battery systems must be functional for cells to work correctly:

1. Muscle battery pack — Your muscles are stacked one on top of the other in a specific order (much like batteries in a flashlight) to form a power pack. Each organ has its own battery pack, which is a stack of muscle batteries. According to Tennant, each stack of muscle batteries corresponds to an acupuncture meridian.

The muscle batteries are surrounded by fascia, which acts as a semiconductor — an arranged metabolic molecule designed to move electrons at the speed of light, but only in one direction. Together, the muscle stack and the surrounding fascia serve as the wiring system for your body, carrying the voltage from the muscle battery inside, out through the fascia and to the appropriate organ.

2. Cell membrane capacitor — Cell membranes are composed of fats called phospholipids, shaped like a circle with two "legs." The circle is an electron conductor and the legs are insulators. They're stacked together so that you have two conductors separated by an insulator, which is the definition of a capacitor.

The difference between a capacitor and a regular battery is when a capacitor discharges, it discharges all of its charge whereas a battery discharges slowly. So, each cell membrane acts like a small battery (capacitor), which is continuously fed electrons from the muscle battery packs.

3. ADP/ATP battery — Inside each cell is yet another rechargeable battery system called adenosine diphosphate/adenosine triphosphate (ADP/ATP). When this battery is charged up, it's called ATP. When the battery's discharged, it's called ADP. Because it's a rechargeable battery system, there's a type of battery charger inside of the cell as well. We call that Krebs cycle, or the citric acid cycle.

The citric acid cycle prefers fatty acids. When sufficient oxygen is available, for every unit of fatty acid you put into the citric acid cycle, you get enough electrons to charge up 38 ATP batteries. If oxygen is unavailable, for every unit of fatty acids you put into the citric acid cycle you only get enough electrons to charge up two of those batteries.

Hence, when oxygen drops, this ADP/ATP battery system becomes very inefficient. "It's like a car that goes from 38 miles a gallon to 2 miles a gallon," Tennant says.

4. The DNA battery — Lastly, there's DNA. The DNA molecule measures 34 by 21 angstroms per double helix cycle.2 The ratio of these numbers is very close to phi and is known as the golden section or golden mean. "Anytime you have something that's a golden mean and expose it to scalar energy … scalar energy implodes into the center and becomes the power supply for DNA," Tennant says.
Fifth Energy System — Structured Water

A fifth system that holds and delivers energy is structured water — negatively charged water found in your cells and extracellular tissues. Typical tap water is H2O, but this fourth phase is actually H3O2. It's more viscous, more ordered and more alkaline than regular water, and the refractive index (optical property) of this water is about 10 percent higher than ordinary water. Its density is also about 10 percent higher and, as mentioned, it has a negative charge (negative electrical potential).

This may provide the answer as to why human cells are negatively charged. Tennant does not go into structured water here, but it's a whole additional component that also plays an important role in health and disease. In summary, the way you recharge this structured water is through sunlight. Sun exposure structures the water in your body, which provides greater energy. To learn more about this, please review "Water Supports Health in Ways You May Never Have Suspected."
What Cells Require for Proper Function

As mentioned, chronic disease is characterized by low voltage. The obvious question then becomes, why won't the battery packs hold a charge? Here, a number of factors can come into play. Among the most important are:

• Thyroid hormones — The thyroid hormone T3 controls the voltage of cell membranes while T2 controls the voltage of the mitochondria. Hence, you need adequate T3 and T2 for things to work. "What I find is that basic to all chronic diseases is that you have to make sure you get the thyroid piece right, because if you don't, then nothing else tends to work correctly," Tennant says.

"One of the problems is doctors are trained to look at thyroid-stimulating hormone (TSH) and sometimes T4. But TSH and T4 could be normal, but if you don't have the cofactors that it takes to convert T4 to T3, you're still hypothyroid at the cell level."

• Dental infections — As mentioned, voltage runs from the muscle battery out through the fascia to the organs. On the way, each muscle battery pack or meridian runs through a specific tooth. There are acupuncture meridian charts showing which meridian corresponds to which tooth.

According to Tennant, teeth act like circuit breakers, so if you have an infection in a tooth, it will lower the voltage, eventually turning the voltage off in that circuit. When that happens, the organs powered by that particular circuit will begin to malfunction.

• Scars — According to Tennant, scars can significantly inhibit or drain voltage. To treat scars, Tennant uses essential oils in combination with his proprietary device called the Biomodulator/Biotransducer. "Just put the Biotransducer over [the scar] until you feel the magnetic fields go away. That opens up the scar and now the voltage goes through it," he says. "It takes about three minutes and works great."
Emotions Create Distorted Magnetic Fields That Lower Voltage

Another really important factor that lowers your body voltage are stuck, negative emotions. Your body actually stores emotions as magnetic fields. Tennant explains:

"If you put a magnetic field in one of the body's circuits, it simply blocks the flow of electrons. So, what we found is that one of the most important things that start chronic disease is actually emotions. You can identify these emotional magnetic fields in a variety of different ways.

Work by Eileen McKusick and others have shown we're all surrounded by this magnetic field. It goes out about 5 feet … [One of the things McKusick taught is you can take a tuning fork, strike it and you'll hear it hum.

As you move it through the field, when it hits one of these areas of emotional distortion, its pitch goes deeper. You can actually hear it. If you can put a pendulum right where you find it, you'll see the pendulum spins counter-clockwise if there's an emotional distortion there. It spins clockwise if there isn't."

To erase the aberrant magnetic fields caused by negative emotions, Tennant applies a stronger magnetic field using his Biomodulator, which not only can transfer electrons but also put out a variety of waveforms, including scalar energy.
Treating Macular Degeneration

Today, Tennant no longer practices general ophthalmology. The only eye problems he treats are macular degeneration and glaucoma, using voltage-based techniques. The macula is on the stomach meridian. "The reason people get macular degeneration is that they lose the minus 50 millivolts they need to make new cells every 48 hours," he says. "As those cells wear out, they can't get replacements."

To address it, you need to determine why there's deficient voltage in the stomach meridian. You also need to make sure you're giving your body all the materials needed to replace those macular cells. Nerve cells are 50 percent cholesterol by weight, so it's nearly impossible to reverse macular degeneration if you're on a statin drug, as you will not have enough cholesterol in your system.

Other important nutrients are animal-based omega-3 fats and fulvic acid, typically sold as "fulvic trace minerals," which provides vitamins, minerals and amino acids.

"Fulvic acid is a primary control of cell membranes because it's one of the few substances that can be either plus or minus, as it needs to be," Tennant explains. "When we take that, it provides the things we need. Of course, there's research coming out now that shows not only does it correct mineral deficiencies, but it begins to help with the way our intestinal cells interlock, and so on.

Also, fulvic acid is a great way to get rid of heavy metals because [it goes] inside the cell, grabs the metal, pulls it out, hands it off to the humic, which then takes it out of your body. In intravenous chelation, the chelating materials can only get to extracellular things, because they won't go inside the cells where almost all the metals reside."

Astaxanthin, a potent antioxidant, can also be quite beneficial. Since the macula replaces itself every 48 hours, people with dry macular degeneration may start noticing results in as little as three or four days, provided you've addressed the nutritional component as well. In many cases, Tennant has been able to restore vision to within the normal reading range.

Wet macular degeneration is more difficult, as the bleeding causes scarring and new cells cannot eliminate the scar. In these cases, the goal is to stabilize the disease and prevent further deterioration.
Treating Glaucoma

To treat glaucoma, you have to treat the liver/gallbladder circuit, as the optic nerve is on the liver/gallbladder meridian. "The optic nerve replaces itself every eight months if it has the 50 millivolts to do it," he says. "What you'll find in every glaucoma patient is that the polarity in the liver meridian has dropped down past zero, so it's an electron stealer instead of an electron donor."

You also need to treat the sympathetic system, which controls lymphatics, because the outflow channel of your eye is part of the lymphatic system. So, "to fix glaucoma, you look at both the sympathetic and parasympathetic and figure out why that's not balanced, and then you fix the liver/gallbladder circuit," Tennant says. Since it takes eight months to replace the optic nerve, it takes longer to notice results when treating glaucoma. Also, you're also more likely to merely stabilize the disease than reverse it.
More Information

If you've enjoyed this conversation, I would strongly encourage you to join us at the ACIM conference in Orlando, Florida, November 2 through 4. The event is being held at the Florida Conference and Hotel Center. Both Tennant and I, along with many other outstanding speakers, like Steven Sinatra, Jonathon Wright and Lee Cowden, all of whom I have previously interviewed, will be there. You can see the rest of the amazing speakers on the ACIM event page.

If you are a physician and are interested in learning about how you can use the ketogenic diet and other therapies for cancer, heart disease, Lyme and neurodegenerative diseases like Alzheimer's and Parkinson's, please be sure and come. If you are a patient, there will be a separate and less expensive track on the same date and location. However, you will need to come back to this page at a later date, as the registration page for the event is still unavailable.

To learn more about how body voltage dictates health and disease, be sure to pick up a copy of Tennant's book, "Healing Is Voltage: The Handbook." You can also learn more on his website, TennantInstitute.com. There you'll also find contact information for his Dallas-based clinic.

"Again, you have to do everything it takes to make new cells work. The voltage piece is basic. If you don't do that, then nothing works. Even if you eat a perfect diet but don't have voltage in the digestive system, you're still starving to death. You have to have the voltage. You have to have the nutrition. You have to deal with the toxins. You have to do all of those," Tennant says.
 

Alton

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#18
A funny thing happened on the way to the opioid crisis...

http://www.washingtontimes.com/news/2017/oct/17/opioid-deaths-drop-pot-legal-colorado/


Countering the opioid epidemic: Colorado overdose deaths decline after marijuana legalized
Cheryl K. Chumley
The Washington Times
Tue, 17 Oct 2017 00:00 UTC


© Real Leaders
A new study has found that fewer individuals died from opioid overdoses in one state where marijuana has been legalized.

Interesting. And worthy of more, much more study.

This preliminary finding is hardly a reason to legalize marijuana for recreational use. But it does seem to suggest a deeper look at the medical uses of marijuana might be warranted. After all, it's been long known that marijuana is effective at easing pain, particularly for those suffering from chronic ailments, like cancer.

Opioids, meanwhile, are on their way out. The tea leaves point that way. The White House has called for crackdowns; pharmacies are beginning to listen; insurance companies are starting to pull back from payments.

Yet chronic pain sufferers are still - well, suffering.

So if marijuana is a feasible alternative, it should be explored.

The study looked at Colorado.

Researchers found that the start of legal marijuana sales in the state actually coincided with a drop in prescription opioid deaths due to overdose.

In fact, when the numbers were looked at, when the statistics were analyzed, it appeared that nearly one fewer person died per month from opioid-related overdose since 2014, when the state's marijuana sales law went into effect.

That's pretty significant.

Researchers haven't drawn a direct parallel between legalized marijuana and the opioid death drop - yet. But they are saying the two factors are "associated" and ought to be studied more.

"These initial results clearly show that continuing research is warranted as data become available, involving longer follow-ups and additional states that have legalized recreational cannabis," the authors of the study wrote, the Denver Post reported.

Of course, the study has its doubters. It's far from conclusive; it's hardly cause to embrace marijuana as a miracle drug and speed through its legalization into states around the nation.

But as opioids move black market, and pain sufferers are left hanging, it's only common sense, not to mention compassionate, to look for new medical treatments to fill the pill void. If it's marijuana that's the answer, then so be it.
 

southfork

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#19
Had my gall bladder taken out 2 weeks ago tomorrow, they did the laparoscopy surgery , had bad stomach pains, gas over a year and 1/2, finally went to new doctor, he had sonogram and hida scan done of gall bladder, hida scan showed less that 5% ejection fraction of gb, still have some bloating,gas, light nausea and pain from surgery.
 

Alton

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#20
If this is NOT snake oil it will be nothing short of revolutionary.


New therapy device heals the body by reprogramming cells
Mae Chan
Prevent Disease
Wed, 25 Oct 2017 16:53 UTC


© God & Science Org
Researchers have developed a device that can switch cell function to rescue failing body functions with a single touch. The technology, known as Tissue Nanotransfection (TNT), injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions.

Although cellular therapies represent a promising strategy for a number of conditions, current approaches have faced major translational hurdles, including limited cell sources and the need for cumbersome pre-processing steps.

A new device developed at The Ohio State University can start healing organs in a "fraction of a second," researchers say.

The technology has the potential to save the lives of car crash victims and even deployed soldiers injured on site. It's a dime-sized silicone chip that "injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions," according to a release.

In the study published in Nature Nanotechnology, first author Daniel Gallego-Perez of Ohio State demonstrated that the technique worked with up to 98 percent efficiently.



In lab tests, one touch of TNT completely repaired injured legs of mice over three weeks by turning skin cells into vascular cells.

And, it not only works on skin cells, it can restore any type of tissue, Chandan Sen, director of the Center for Regenerative Medicine and Cell-Based Therapies, said. For example, the technology restored brain function in a mouse who suffered a stroke by growing brain cells on its skin.

"It takes just a fraction of a second. You simply touch the chip to the wounded area, then remove it," said Chanda n Sen, PhD, director of the Center for Regenerative Medicine and Cell-Based Therapies at The Ohio State University Wexner Medical Center. "At that point, the cell reprogramming begins."

This is a breakthrough technology, because it's the first time cells have been reprogrammed in a live body. Current cell therapy methods are high risk, like those that introduce a virus and include multiple steps. There are no known side effects to TNT and treatment is less than a second, Sen said.

"This technology does not require a laboratory or hospital and can actually be executed in the field," Sen said. "It's less than 100 grams to carry and will have a long shelf life."

In a series of lab tests, researchers applied the chip to the injured legs of mice that vascular scans showed had little to no blood flow. "We reprogrammed their skin cells to become vascular cells," Sen said. "Within a week we began noticing the transformation."

By the second week, active blood vessels had formed, and by the third week, the legs of the mice were saved--with no other form of treatment.

"It extends the concept known as gene therapy, and it has been around for quite some time," said study collaborator James Lee, PhD, a professor of chemical and biomolecular engineering at Ohio State. "The difference with our technology is how we deliver the DNA into the cells."

It is awaiting FDA approval, but Sen, who has been working on this for four years, expects TNT will be tested on humans within the year. He says he's talking with Walter Reed National Medical Center now.

"We are proposing the use of skin as an agricultural land where you can essentially grow any cell of interest," Sen said.

"What's even more exciting is that it not only works on the skin, but on any type of tissue," Sen said. In fact, researchers were able to grow brain cells on the skin surface of a mouse, harvest them, then inject them into the mouse's injured brain. Just a few weeks after having a stroke, brain function in the mouse was restored, and it was healed.

Because the technique uses a patient's own cells and does not rely on medication, researchers expect it to be approved for human trials within a year.

Sources:
medicine.osu.edu
 

Alton

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#21
Boy! Things got all shuffled around and I wondered what happened to this thread...


Anyway, as if anyone didn't know, BIG pharma funding for med education:

Authors of premier medical textbook didn't disclose $11 million in industry payments
Adam Marcus and Ivan Oransky
Stat News
Tue, 06 Mar 2018 05:53 UTC



1-2: Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2) Hardcover, to be released this year for $224.10
It's a textbook that has graced the shelves of untold thousands of medical students going back decades. Harrison's Principles of Internal Medicine, now in its 20th edition, is a must-read for medical students and young internists. It has been called "the most recognized book in all of medicine."

It's also a case study in hidden conflicts of interest. So says a group of researchers who found that Harrison's and several other leading medical texts failed to disclose financial interests the authors had in the subject matter as well as payments they'd accepted from industry groups.

According to the study, authors for Harrison's received more than $11 million between 2009 and 2013 from makers of drugs and medical devices - not a penny of which was disclosed to readers. One author, a physician, during that period received nearly $870,000 in funding, including for research, according to ProPublica's Dollars For Docs database of payments to doctors from drug companies.

Many Harrison's authors also hold patents in their fields - as many as 23, in one case - another potential conflict of interest that again the books do not disclose to readers.

"These findings indicate that full transparency of [author conflicts] should become a standard practice among the authors of biomedical educational materials," according to the authors, whose study appears in the journal AJOB Empirical Bioethics.

McGraw-Hill, which publishes Harrison's, did not respond to STAT's requests for comment.

Financial disclosures have become de rigueur in scientific journals, where many of Harrison's authors also publish and are subject to guidelines for such disclosures. Textbooks, however, have typically not required disclosures - and that means they've fallen even more behind standard practices.

The researchers, led by Brian Piper, a neuroscientist at the Geisinger Commonwealth School of Medicine in Scranton, Pa., acknowledge that simply looking at patent awards and fees from biomedical companies doesn't prove the existence of biased work. But they note that medical textbooks are enormously influential due to their perceived authority and the wide readership they receive.

'We were not surprised by these findings'

It's not the first time Piper has looked at conflicts of interest in textbooks. In 2015, he and colleagues published a paper finding the same problem in pharmacology textbooks.

"Sadly, after six years doing these types of studies, we were not surprised by these findings," Piper told STAT about his newest study. "However, we continue to be surprised that the publishers and authors of medical textbooks do not have the same transparency standards about conflicts of interest that have become widely accepted for clinical trials and other primary sources."

Some of the potential problems that these conflicts could present occur when textbooks recommend certain treatments, Piper said.

Studies have shown that doctors who take more money - or even free meals - from drug companies are more likely to prescribe brand-name medications than their colleagues who earn less from industry. And in general, it stands to reason that authors who are comfortable with industry funding would be more likely to think of drug treatments than of treatments that might not benefit pharmaceutical companies' bottom lines.

Piper and his colleagues recommend that textbook publishers adhere to the same disclosure standards that journals follow, making sure that readers know about relevant financial relationships. Seems reasonable to us.

Until they do, however, fledgling physicians should be on notice that all those pricey tomes they're buying leave plenty unsaid.
 

Alton

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#22
The following is a good example of what I call "sales propaganda". The "medical community" wants to increase the use of vaccines. In this particular case the failed and deadly Gardisil vaccine ostensibly against the Human Papilloma Virus (HPV) which has been proven to have caused numerous deaths...


Is the oral cancer epidemic in men outwitting natural defenses?
Marie McCullough
The Sacramento Bee
Thu, 08 Mar 2018 10:09 UTC


© Richard Dymond / Bradenton Herald
HPV is human papilloma virus which doctors say can cause infections which can lead to adult cancers including cervical, head, throat, neck and others.
Five years ago, when actor Michael Douglas candidly revealed that his throat cancer was linked to having oral sex, two things happened.

He made headlines that mortified his family. And he helped publicize the fact that a pervasive, sexually transmitted virus called HPV was unleashing an epidemic of oral cancer among men.

Since then, scientists have made headway in figuring out why HPV, the human papillomavirus, has this glaring gender bias. Men are four times more likely than women to be diagnosed with oral cancer, a hard-to-detect, hard-to-treat disease that has overtaken cervical cancer as the most common HPV-related malignancy in the United States.

To be sure, changes in sexual norms over the last few generations have played a role in this alarming trend. But research increasingly shows the real problem is something men have practically no control over: their immune response.

Compared with women, men are more likely to get infected with HPV - including "high-risk" cancer-causing strains. They also are less able to wipe out infection on their own, and more likely to get reinfected. The reasons are unclear.

"There is good evidence that men acquire oral infections more readily than women, even if they have similar sex practices," said Ashish A. Deshmukh, a University of Florida HPV researcher. "And more than the acquisition, it's the persistence of the virus. The clearance rate is not that fast in men."

Michael Becker of Yardley has stepped up as the face of this immunological inequity. The 49-year-old former biotech executive is health-conscious, clean-living, happily married for 26 years - and battling terminal oropharyngeal cancer, the medical term for malignancies in parts of the mouth and throat.

He's also battling the misconceptions and ignorance that keep too many parents from protecting their pubescent children - especially boys - against HPV-driven cancers. Two shots. That's all it takes for the leading vaccine, Gardasil, to prevent most cervical cancers, less common genital malignancies, and the disease that is killing Becker.

"I can't tell you how many emails I got from parents after the CBS segment," he said, referring to a national television interview last month. "They said, 'What do you mean this vaccine is for boys?' and 'What do you mean oral cancer incidence has eclipsed cervical cancer?'"

HPV is a family of more than 100 virus types that can live in the flat, thin cells on the surface of the skin, cervix, vagina, anus, vulva, penis, mouth and throat.

The virus is spread through contact with infected skin, mucous membranes, and bodily fluids. Some types can be passed during intercourse or - as Douglas pointed out - oral sex.

While virtually all sexually active people will get infected at some point, the virus is usually wiped out by the immune system without so much as a symptom.

But not always.

In the cervix, persistent infection with high-risk HPV types can lead to precancerous changes that, left alone, slowly turn malignant. Fortunately, the Pap smear enables the detection and removal of abnormal cells before cancer develops. What's more, age-related changes in cervical cells reduce the risk that HPV will take hold there as women get older.

No such screening test exists for oropharyngeal sites - the tongue, soft palate, tonsils, the throat behind the nasal cavity - and symptoms usually don't appear until cancer is advanced. Becker, for example, had metastatic disease by the time he noticed a lump under his jaw line in late 2015.

Traditionally, smoking and heavy alcohol use are the big risk factors for oral cancer, but the non-HPV tumors linked to these bad habits have been declining in recent years.

HPV-related tumors, in contrast, have increased more than 300 percent over the last 20 years. The virus is now found in 70 percent of all new oral cancers.

About 13,200 new HPV oral cancers are diagnosed in U.S. men each year, compared with 3,200 in women, according to federal data. Treatment - surgery, chemotherapy, radiation - can have disfiguring, disabling side effects. About half of late-stage patients die within five years.

Oral HPV infection rates are skewed by gender, just like the resulting cancers. The latest national estimates of this disparity, published in October, come from Deshmukh and his University of Florida colleagues. They used a federal health survey that collected DNA specimens to estimate that 7.3 percent of men and 1.4 percent of women have oral infections with high-risk HPV types. That translates to 7 million men and 1.4 million women.

The chance of oral infection increases for women as well as men who have simultaneous genital HPV infections or a history of many sex partners, but male infection rates still far surpass female rates.

Patti Gravitt, an HPV researcher at George Washington University, believes these estimates are a bit oversimplified because women counted as uninfected may actually have undetectably low virus levels, or HPV may be hiding in a dormant state in their cells.

Still, Gravitt said the study is in line with others that suggest "men are more susceptible to HPV viral infection than women."

In women, an HPV infection usually sets off the body's defense mechanisms. The immune system makes antibodies that kill off the invader, then immune cells remain on guard, ready to attack if the virus reappears.

But in men, something goes awry. The HIM study - for HPV in Men - documented this by collecting genital, anal, and oral samples from 4,100 unvaccinated men in Florida, Mexico and Brazil between 2005 and 2009. The samples were tested for the presence of two high-risk HPV types and two that cause genital warts.

Among 384 men who developed infections during a 24-month period, only 8 percent produced antibodies. But this response rate varied depending on the site of infection; none of the small number of orally infected men produced antibodies.

Rather than putting the immune system on guard and protecting men from the virus, infection sharply increased the chance of getting infected again with the exact same HPV type. And many men who got reinfected were celibate at the time.

How could this be? Anna R. Giuliano, the researcher at the Moffitt Cancer Center in Tampa, Fla., who led the HIM study, said recurring infections may be due to reactivation of dormant virus, or to auto-inoculation - the man spreads infection from one part of his body to another. Or to something else entirely.


While the scientific understanding of this puzzle is evolving, one implication is clear. "HPV vaccination is the only reliable method to ensure immune protection against new HPV infections and subsequent disease in males," Giuliano and her co-authors declared in a recent paper.
 

spinalcracker

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#23
Good article that explains a few things about cannabinoids and how our carbon units process them.......
I broke my neck in 5 places C3,4,& 5 in 2014....Lifeflight from Hugo Colorado to Denver after rollover 25 miles south of Hugo....
Long story short , I made pain patches from my pot and put them on my incision.
Never took any opiates for pain.
Never took nothing.
I still take zero meds.
Prescription or over the counter.
I just eat right , talk right , and spit white.....

http://drug-dev.com/Main/Back-Issues/THERAPEUTIC-FOCUS-Direct-Effects-Cannabinoid-Thera-1132.aspx

THERAPEUTIC FOCUS - Direct Effects™ Cannabinoid Therapy: Medical Cannabis Without Psychoactive & Systemic Effects

MEDICAL CANNABIS CONTROVERSY



There is no greater medical therapeutics “double-edged sword” than cannabis. Benefits in treating symptoms of diverse conditions have been known for thousands of years. Its psychoactive effects have caused abuse and labeling as a “gateway drug” for more addictive compounds. No class of compounds has generated more controversy and stigma.



Although defined under federal law as having no medical use, US Patent No. 6630507 was granted in 2003 to the US Department of Health and Human Services for cannabinoids to treat a wide range of diseases. Cannabinoids as Antioxidants and Neuroprotectants claims exclusive rights for treating Alzheimer’s, Parkinson’s disease, stroke; and states of oxidative stress, such as heart attack, Crohn’s disease, diabetes, and arthritis.1


Up to the 1900s, medical cannabis was widely marketed and prescribed in the US. In 1890, Eli Lilly and Parke Davis joint-ventured to breed cannabis in Greenfield, IN, producing Cannabis Americana. In 1937, Congress enacted cannabis prohibition.2



ENDOCANNABINOID SYSTEM (ECS)



The endocannabinoid system, ECS, consists of cannabinoid receptors located throughout the mammalian nervous system. ECS is involved in a variety of physiological processes, including neurological functions dealing with pain, mood, memory, movement, and sensation. Immune function and cell homeostasis are also maintained by ECS. ECS mediates psychoactive effects of cannabis. Cannabinoids are a diverse class of compounds that include those in cannabis.3,4

2018-05-06 18.24.45.jpg F1.jpg F2.jpg F3.jpg F4.jpg
 

Alton

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How about Alt/Alt medicine! Cannabinoids in and from other plants! Well, maybe. The following article is interesting and no trouble with the law...

Foods with healing cannabinoids



Anna Hunt
Waking Times
Mon, 24 Jul 2017 18:36 UTC






You can still benefit from the same cannabinoids that give the cannabis plant its medicinal properties, without consuming cannabis. There are several foods rich in cannabinoids that benefit the body's endocannabinoid system. This system is responsible for helping the body maintain internal balance, also called homeostasis.

Foods that support the function of the endocannabinoid system are pivotal to overall health and well-being. Here are five foods that contain healing cannabinoids and offer therapeutic benefits similar to cannabis.

Black Pepper - Piper nigrum


Black pepper has much in common with cannabis. The plant's aroma molecule, called beta-caryophyllene (BCP), functions as a cannabinoid. Similar to other plant-based cannabinoids, BCP binds with the CB2 receptors. This gives black pepper its therapeutic effect of reducing inflammation. Various research has suggested that BCP could be used for the treatment of arthritis and osteoporosis. In addition, it may potentially increase the effectiveness of certain anti-cancer drugs.

Cacao - Theobroma cacao


The cacao plant has many therapeutic properties. It affects the endocannabinoid system by deactivating the enzyme called FAAH. This enzyme typically breaks down the endocannabinoid known as anandamide. Scientists identify anandamide as the body's natural version of THC. That's why eating delicious, organic dark chocolate can give you the sensation of being relaxed and happy.

Researchers at the Neurosciences Institute of San Diego were able to back up the claims that chocolate does contain three compounds that act as healing cannabinoids.

Black Truffles - Tuber melanosporum


Similarly to cannabis and cacao, black truffles also create anandamine. Some have dubbed anandamide "the bliss molecule," because it helps the body regulate mood. In addition, it regulates how we perceive pain. It does this by binding with CB1 receptors that are present in the central nervous system.

Kava - Piper methysticum


Typically used in a medicinal tea, kava can ease anxiety and chronic pain. It is also induces a sedative effect. Hence, in certain cultures kava tea has become a popular natural anxiety remedy.

Kava is the national drink of Fiji. It is made by mixing the powdered kava root of this peppery plant with water. Similar to THC, components in kava bind to CB1 receptors in brain locations associated with addiction and cravings. For decades, Pacific Islanders in Fiji have been using kava as a treatment for addiction.

Coneflower - Echinacea


This plant is well-known for its ability to help the body fight off the common cold. It is also used to relieve anxiety, fatigue, migraines, and arthritis. Echinacea is a bit different than cannabis because it uses cannabimimetics instead of cannabinoids to engage the endocannabinoid system, particularly the CB2 receptor. Similar to THC in cannabis, the N-alkyl amides (NAAs) in Echinacea are responsible for regulating the immune system, pain and inflammation.

As an aside, you may also find it interesting that hemp seeds and hemp seed oil contain very low concentration of cannabinoids, at less than 25 parts per million (ppm). Compare this to CBD oil extracts produced from cannabis plant flowers, which have 150,000 ppm CBD. (source) Cannabidiol (CBD) is the most common cannabinoid in most cannabis plants.

Sources

marijuana.com
wakingtimes.com
 

Alton

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Well, well, well...here's a little food history American style...break out the LARD!

It really was garbage! - The shocking origin of vegetable oil 



Dr. Jason Fung
Medium
Wed, 22 Aug 2018 21:15 UTC






© Medium
Looking back over the last 40 years, it's hard to understand how we could have been so gullible. We believed that fat, and more specifically saturated fat (found primarily in animal foods), was thought to increase cholesterol and cause heart disease. Instead, we should switch to 'heart healthy' vegetable oils, like cottonseed, corn, safflower and soy oils. But recent evidence suggests this was a Faustian bargain. The industrially processed seed oils were much, much worse. It was all a terrible mistake that began with Crisco.

Cotton plantations for fabric were cultivated in the United States as early as 1736. Prior to this, it was largely an ornamental plant. At first, most cotton was home-spun into garments, but the success of the crop meant that some could be exported to England. From a modest 600 pounds of cotton in 1784, it grew to over 200,000 by 1790. The invention of the cotton-gin by Eli Whitney in 1793 led to a staggering 40,000,000 pounds of cotton production.

But cotton is actually two crops - the fiber and the seed. For every 100 pounds of fiber, there was 162 pounds of cotton seeds which were largely useless. Only 5% of this seed was required for planting. Some could be used for livestock feed but there was still a mountain of garbage. What could be done with this garbage? Mostly it was left to rot or simply dumped illegally into rivers. It was toxic waste.

Meanwhile, in the 1820's and 1830's increased demand for oil used in cooking and lighting from a rising population and decreased supply of whale oil meant that prices rose steeply. Enterprising entrepreneurs tried to crush the worthless cotton seeds to extract the oil, but it was not until the 1850s that the technology matured to the point that commercial production could commence. But in 1859, something happened that would transform the modern world. Colonel Drake struck oil in Pennsylvania in 1859 introducing a massive supply of fossil fuels to the modern world. Before long, the demand for cottonseed oil for lighting had completely evaporated and cottonseeds went back to being classified as toxic waste.

With lots of cottonseed oil, but no demand, it was added illicitly to animal fats and lards. There was no evidence that this was, in any way safe for human consumption. We don't eat our cotton T-shirts after all. Similarly, cottonseed oil, being light in flavor and slightly yellow was blended with olive oil to reduce costs. This led to Italy completely banning the adulterated American olive oil in 1883. The Proctor & Gamble company used cottonseed oil for the manufacture of candles and soap, but soon discovered that they could use a chemical process to partially hydrogenate cottonseed oil into a solid fat that resembled lard. This process produced what are now called 'Trans' fats, making this product extremely versatile in the kitchen, even if nobody actually knew whether we should be shoving this former toxic waste into our mouths.

It made pastry flakier. It could be used for frying. It could be used in baking. Was it healthy? Nobody knew. Since this new-fangled semi-solid fat resembled food, and the decision was made to market this as food. They called this revolutionary new product Crisco, which stood for crystallized cottonseed oil.

Crisco was skillfully marketed as a cheaper alternative to lard. In 1911, Proctor & Gamble launched a brilliant campaign to put Crisco into every American household. They produced a recipe book, all of which use Crisco, of course, and gave it away for free. This was unheard of, at the time. Advertisements of that era also proclaimed that Crisco was easier to digest, cheaper and healthier due to its plant origins. That cottonseeds were essentially garbage was not mentioned. Over the next 3 decades, Crisco and other cottonseed oils dominated the kitchens of America, displacing lard.

By the 1950s, cottonseed oil itself was getting expensive and Crisco once again turned to a cheaper alternative, soybean oil. The soybean itself took an improbable route to the American kitchen. Originally from Asia, soybeans were introduced to North America in 1765, having been domesticated in China as far back as 7000 BC. Soybeans are approximately 18% oil and 38% protein, making it ideal as food for livestock or for industrial purposes (paint, engine lubricants).

Since Americans ate almost no tofu prior to World War II, little or no soybeans made it into the American diet. Things began to change during the Great Depression, when large areas of the United States were stricken by severe drought - the Dust Bowl. Soybeans could help regenerate the soil through their ability to fix nitrogen. It turns out that the great American Plains were ideal for growing soybeans, so they quickly became the second most lucrative crop, just behind corn.


© Medium
Meanwhile, in 1924, the American Heart Association was formed. It was not the powerful behemoth it is today, but just a collection of heart specialists meeting occasionally to discuss professional matters. In 1948, this sleepy group of cardiologists were transformed by a $1.5 million donation from Proctor & Gamble, (maker of hydrogenated trans-fat laden Crisco - yay). The war to replace animal fats with vegetable oils was on. The Faustian deal was made - the health of a nation for some filthy lucre $$$.

By the 1960s and 1970s, led by Ancel Keys, the new dietary villain was saturated fats, the type found in more frequently in animal foods like meat and dairy. The American Heart Association (AHA) wrote the world's first official recommendations in 1961 recommending that we "reduce intake of total fat, saturated fat and cholesterol. Increase intake of polyunsaturated fat". In other word, avoid animal fat and eat 'heart-healthy' vegetable oils, high in polyunsaturated fats, like Crisco. This advice carried forward to the influential 1977 Dietary Guidelines for Americans.

The American Heart Association threw its now considerable market-moving influence into making sure that America ate less fat, and less saturated fat. The Center for Science in the Public Interest (CSPI), for example, declared the switch from beef tallow and other saturated fats to trans-fat laden partially hydrogenated oils as "a great boon to Americans' arteries'. Don't eat butter, they said. Instead, replace it with the partially hydrogenated vegetable oil (read: trans-fats) known as margarine. That edible tub of plastic was much healthier than the butter that humans had been consuming for at least 3000 years, they said. Even as late as 1990 the CPSI refused to acknowledge the dangers of trans fats writing, famously their bottom line - "Trans, shmans. You should eat less fat".


© Medium
In 1994, the CSPI struck fear into movie-goers hearts with a brilliant scare campaign. Movie popcorn at that time popped in coconut oil, which was largely saturated fats. The CSPI declared that a medium sized bag of movie popcorn had more 'artery clogging fat than a bacon-and eggs breakfast, a Big Mac and fries for lunch, and a steak dinner with all the trimmings - combined!" Movie popcorn sales plunged, and theatres raced to replace their coconut oil with partially hydrogenated vegetable oils. Yes, trans-fats. Before that, the war to rid the American public of beef tallow, the secret ingredient of McDonald's French fries, resulted in the switch to, you guessed it, partially hydrogenated vegetable oils.

But the story was not yet done. By the 1990s, these trans fats that the AHA and the CSPI told us were supposed to be so healthy for us were implicated as major risk factors for heart disease. New studies now indicated that trans-fats just about doubled the risk of heart disease for every 2% increase in trans-fat calories. By some estimates, trans-fats were responsible for 100,000 deaths. The very 'heart-healthy' foods the AHA recommended we eat were actually giving us heart attacks. The irony. The irony. By November 2013, the US Food and Drug Administration removed partially hydrogenated oils from the list of human foods 'Generally Recognized as Safe'. Yes, the AHA had been telling us to eat poison for decades.

Industrial seed oils, such as cottonseed are high in the omega-6 fat linoleic acid. Linoleic acid is called the parent omega-6 fat because other omega-6 fats, such as gamma linolenic acid (GLA) and arachidonic acid are formed from it. During evolutionary times, the intake of linoleic acid would have only come from whole foods, such as eggs, nuts and seeds, whereas isolated omega-6 intake from industrial seed oils would have been zero. However, Crisco, introduced an isolated and adulterated type of linoleic acid into our diet. Thus, the intake of linoleic acid has dramatically increased and from a source that humans have never consumed before. These omega-6 seed oils can now be found in nearly all manufactured foods and are also found in grocery aisles in plastic bottles for cooking. Unfortunately, these oils are highly susceptible to heat, light, and air and are exposed to all three during their processing. Thus, while linoleic acid coming from whole foods such as nuts and seeds may actually be beneficial, the adulterated linoleic acid found in industrial seed oils is not.

© Medium
So how do we know which are healthy fats, and which are unhealthy fats? Unsurprisingly, natural fats, whether they come from animal (meat, dairy) or plant sources (olive, avocado, nut) are generally healthy. Highly processed, industrial seed oils tend to be unhealthy. Let's face the facts - we ate vegetable oils because they were CHEAP, not because they were healthy.

For more information see the fantastic book by Nina Teicholz The Big Fat Surprise.

Dr.Jason Fund - Nephrologist. Special interest in type 2 diabetes reversal and intermittent fasting. Founder of Intensive Dietary Management Program.
 

GOLDBRIX

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GAWD, I remember all the baking my mom did when I was a kid, and the cans of CRISCO that came through her kitchen.
If she didn't use it for pies and cakes she was frying chicken in it.
I bet her, all my aunts, and grandmother was the financial support for at least one story of the P&G Building in Cinci.